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IC:C12M AND EN_ALLTXT:(coronavirus OR coronaviruses OR coronaviridae OR coronavirinae OR orthocoronavirus OR orthocoronaviruses OR orthocoronaviridae OR orthocoronavirinae OR betacoronavirus OR betacoronaviruses OR betacoronaviridae OR betacoronavirinae OR sarbecovirus OR sarbecoviruses OR sarbecoviridae OR sarbecovirinae OR "severe acute respiratory syndrome" OR sars OR "2019 ncov" OR covid)

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Analysis

1.WO/2022/015731ANTERIOR NARES SWAB AND USES THEREOF
WO 20.01.2022
Int.Class A61J 1/05
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
1Containers specially adapted for medical or pharmaceutical purposes
05for collecting, storing or administering blood, plasma or medical fluids
Appl.No PCT/US2021/041429 Applicant PRESIDENT AND FELLOWS OF HARVARD COLLEGE Inventor SPRINGER, Michael
The technology described herein is directed to an anterior nares swab that is automation compatible. In one aspect, the swab comprises a cap, a threaded portion, a neck, and a sample collection head. The cap can be integrally and/or monolithically formed with any one or more of the threaded portion, the neck, and the sample collection head; or can be removably coupled to any one or more of the threaded portion, the neck, and the sample collection head. In additional aspects, described herein are kits comprising said swabs and methods of using said swabs.
2.WO/2022/020259METHODS AND DEVICES FOR DETECTING AND SEQUENCING SARS-COV-2
WO 27.01.2022
Int.Class C12Q 1/70
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
70involving virus or bacteriophage
Appl.No PCT/US2021/042228 Applicant CENTRILLION TECHNOLOGIES, INC. Inventor ZHOU, Wei
The present disclosure provides methods, reagents, microarray, and software products for detecting and sequencing at least part of the SARS-CoV-2 viral RNA. The microarray and methods of the present disclosure can be used to perform simultaneous detection of SARS-CoV-2 virus and other pathogens including respiratory pathogens.
3.WO/2021/252671FLOW CELL SYSTEMS AND DEVICES
WO 16.12.2021
Int.Class C12Q 1/6837
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6813Hybridisation assays
6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
6837using probe arrays or probe chips
Appl.No PCT/US2021/036670 Applicant ELEMENT BIOSCIENCES, INC. Inventor GUO, Minghao
Flow cell devices, cartridges, and systems are described that provide reduced manufacturing complexity, lowered consumable costs, and flexible system throughput for nucleic acid sequencing and other chemical or biological analysis applications. The flow cell device can include a capillary flow cell device or a microfluidic flow cell device.
4.WO/2021/195544NOVEL ANUCLEATED CELLS FOR THE TREATMENT OF DISEASES
WO 30.09.2021
Int.Class A61K 35/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
Appl.No PCT/US2021/024442 Applicant PLATELET BIOGENESIS, INC. Inventor HETT, Sunita R.
The present disclosure takes advantage of non-naturally existing, novel, anucleated platelets or platelet-like cells or platelet variants (collectively referred to as PECs) or derivatives thereof (i.e., genetically engineered), which share at least one common receptor, ligand or an antigen with endogenous cells that are targets for autoantibodies and effectuate their clearance. The present disclosure also takes advantage of viral adhesion or entry receptors or genetically engineered PECs or derivatives thereof, which are engineered to express viral adhesion or entry receptors, that specifically binds to viral proteins on viruses or viral particles and effectuate their clearance.
5.WO/2023/275355REACTOR SYSTEM AND METHODS FOR USING THEREOF
WO 05.01.2023
Int.Class C12M 1/36
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
36including condition or time responsive control, e.g. automatically controlled fermentors
Appl.No PCT/EP2022/068259 Applicant QUANTOOM BIOSCIENCES S.A. Inventor CASTILLO, José
Disclosed herein are systems, methods and devices for the continuous production and processing of compounds, including biopharmaceutical compounds. The system and devices are operated in an automated manner and capable of operation under Good Manufacturing Practice (GMP)- compliant conditions.
6.WO/2021/250274DEVICE AND METHOD FOR CAPTURING AND ANALYSING AIRBORNE ORGANISMS
WO 16.12.2021
Int.Class C12Q 1/70
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
70involving virus or bacteriophage
Appl.No PCT/EP2021/065932 Applicant CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) Inventor ALCAMI PERTEJO, Antonio
The present invention refers to a device comprising polytetrafluorethylene (PTFE) filters and the use of the same for collecting, detecting and identifying organisms present in air ecosystems. The invention also provides a method suitable for the capture, detection and identification of whole airborne biological particles, including viruses and other important air pathogens, which involves the use of the device. This method allows toperform organism, preferably viral, metagenomics to sequence all DNA and RNA organisms captured in the filters. This methodology may be used to detect, for instance, SARS-CoV2 particles in air samples.
7.3119256RAPID DIAGNOSTIC SYSTEM USING TARGETED ANTISENSE OLIGONUCLEOTIDE CAPPED PLASMONIC, NANOPARTICLES
CA 12.12.2021
Int.Class C12Q 1/6818
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6813Hybridisation assays
6816characterised by the detection means
6818involving interaction of two or more labels, e.g. resonant energy transfer
Appl.No 3119256 Applicant UNIVERSITY OF MARYLAND, BALTIMORE Inventor PAN, DIPANJAN
The present disclosure relates to a nanotechnology-based molecular sensing system, compositions, and methods that can be adapted to accurately detect a target gene in clinical samples, using anti-sense oligonucleotide capped plasmonic nanoparticles for selective detection of biological pathogens.
8.WO/2022/242513SYSTEM AND METHOD FOR AUTOMATIC NUCLEIC ACID EXTRACTION AND QUIALITATIVE ANALYSIS
WO 24.11.2022
Int.Class C12M 1/42
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
42Apparatus for the treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic wave
Appl.No PCT/CN2022/092113 Applicant TAIWAN ADVANCED NANOTECH INC. Inventor CHIEN, Chien-Hsing
A system(1) and method for automatic nucleic acid extraction and qualitative analysis are provided. The system(1) comprises a magnetic rotary mixer(100) which comprises a plurality of magnetic rods(101) for generating magnetism, configured to be retractable from the magnetic rotary mixer(100); a plurality of spin shaft(102) for mounting tips(103), and the plurality of magnetic rods(101) extend therein; an auto stage(200) comprises a plate holder(201), which allows a plate(300) place thereon; a mixer holder(203) to hold the magnetic rotary mixer(100) over the plate holder(201); and a heat plate(202), disposed under the plate holder(201) for heating the plate(300). An automated high-throughput nucleic acid extraction and qualitative diagnosis with high efficiency and high accuracy is easy to interpret for operators. The nucleic acid extraction and molecular detection can be completed at one time in a single device.
9.WO/2021/209009METHODS AND COMPOSITIONS FOR HIGH-THROUGHPUT TARGET SEQUENCING IN SINGLE CELLS
WO 21.10.2021
Int.Class C12Q 1/68
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
Appl.No PCT/CN2021/087517 Applicant SINGLERON (NANJING) BIOTECHNOLOGIES, LTD. Inventor FANG, Nan
Provided include methods, compositions and kits for single cell target sequencing, including but not limited to, high-throughput detection of nucleic acid sequences of single cell T cell receptor, high-throughput detection of expressed viral sequences in host cells, detection of cancer druggable mutations (e.g., lung cancer druggable mutations) in single cells, and simultaneous detection of targeted regions and whole transcriptome in single cells.
10.WO/2022/232261IMPROVED DIAGNOSTICS FOR EMERGING DISEASE
WO 03.11.2022
Int.Class G01N 33/53
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
Appl.No PCT/US2022/026522 Applicant TRELLIS BIOSCIENCE, LLC Inventor RAMEL, Urs A.
A microfluidic device, and method of using the device, the device comprising: a housing; a substrate adapted to be disposed within the housing, the substrate comprising: a sample port adapted to receive a sample and extract at least one analyte from the sample into a liquid assay sample, a sample well coupled to the sample port, a reaction well, a first microfluidic channel coupled at a proximal end to the sample well, and a second microfluidic channel coupled at a distal end to the reaction well, wherein a distal end of the first microfluidic channel and a proximal end of the second microfluidic channel are isolated from each other via a fluid channel seal, a controller adapted to break the fluid channel seal and to meter the liquid assay sample from the sample well into the reaction well for an assay.