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IC:G01N33/48

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Analysis

1.WO/2022/128917ANALYSIS SYSTEM AND METHOD FOR TESTING A SAMPLE
WO 23.06.2022
Int.Class C12Q 1/6825
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6813Hybridisation assays
6816characterised by the detection means
6825Nucleic acid detection involving sensors
Appl.No PCT/EP2021/085490 Applicant BOEHRINGER INGELHEIM VETMEDICA GMBH Inventor HANSEN, Soeren
An analysis system and a method for testing a biological sample is proposed, wherein a plurality of assays selected from at least two assays from a group consisting of a protein assay for detecting a target protein, a nucleic-acid assay for detecting a target nucleic-acid sequence and/or an aptamer assay for detecting another target analyte are carried out preferably simultaneously in a common sensor array by means of a sensor apparatus.
2.WO/2022/131857BIOSENSOR USING PET SUBSTRATE, FABRICATION METHOD THEREFOR, AND METHOD FOR INSPECTING SENSITIVITY OF MICROORGANISM TO ANTIBIOTIC BY USING SAME
WO 23.06.2022
Int.Class G01N 27/02
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
02by investigating impedance
Appl.No PCT/KR2021/019292 Applicant PROTEOMETECH INC. Inventor LIM, Kook Jin
The present invention relates to a biosensor for inspecting sensitivity of a microorganism to an antibiotic, a fabrication method therefor, and a method for inspecting sensitivity of a microorganism to an antibiotic by using same, wherein the biosensor comprises: a substrate including polyethylene terephthalate; and a sensor part formed on one surface or both surfaces of the substrate and comprising an electrode inclusive of a first electrode and a second electrode which interdigitate with each other.
3.WO/2022/132787SYSTEMS AND METHODS FOR CELL ENRICHMENT, ISOLATION AND FORMULATION
WO 23.06.2022
Int.Class C12M 1/26
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
26Inoculator or sampler
Appl.No PCT/US2021/063332 Applicant GLOBAL LIFE SCIENCES SOLUTIONS USA LLC Inventor HEIMBERG, Yorick
An apparatus for magnetic cell isolation includes a base, a stopcock manifold interface located on the base and configured to receive a stopcock manifold of a cell processing kit, a magnetic field generator located within the base, and a slot formed in the base, the slot configured to removably receive a magnetic cell isolation holder. The magnetic field generator is movable into and out of engagement with the magnetic cell isolation holder.
4.WO/2022/133102PI3K INHIBITORS FOR PROTECTION AGAINST GLUCOCORTICOID-INDUCED ATROPHY
WO 23.06.2022
Int.Class A61K 39/39
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
39characterised by the immunostimulating additives, e.g. chemical adjuvants
Appl.No PCT/US2021/063832 Applicant NORTHWESTERN UNIVERSITY Inventor BUDUNOVA, Irina
Provided herein are methods of treating and preventing steroid-induced atrophy (e.g., skin atrophy, osteoporosis, etc.) by the administration of PI3K/Akt/mTOR inhibitors and pharmaceutical compositions and combinations therefor.
5.WO/2022/130251SEROLOGICAL TEST TO AID DIAGNOSIS OF GLIOBLASTOMA MULTIFORME
WO 23.06.2022
Int.Class G01N 33/543
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
Appl.No PCT/IB2021/061789 Applicant UNIVERSITÀ DEGLI STUDI DI ROMA "LA SAPIENZA" Inventor CARACCIOLO, Giulio
The invention relates to a method for the diagnosis of glioblastoma multiforme which comprises the use of graphene oxide nanoparticles and a subsequent image analysis, a method of screening or monitoring of pathological and non-pathological patients to identify pathological patients at risk of glioblastoma multiforme, which comprises the use of graphene oxide nanoparticles and subsequent image analysis, a kit comprising reagents for the early diagnosis of glioblastoma multiforme.
6.WO/2022/129171URINALYSIS DEVICE
WO 23.06.2022
Int.Class G01N 33/493
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
483Physical analysis of biological material
487of liquid biological material
493urine
Appl.No PCT/EP2021/085892 Applicant USENSE Inventor OUERIEMMI, Amir
The present invention relates to a hand-held urinalysis device (1) comprising a handle (11) and a measuring head (12) configured to be immersed in a urine sample, wherein the measuring head (12) comprises a conductivity probe; a lighting module (14) configured to emit light; and a multispectral optical sensor (13) configured to receive light. The invention also relates to methods of urine analysis and a urinalysis system.
7.WO/2022/129336PH RESPONSIVE CYANINE DYES AND CONJUGATES THEREOF
WO 23.06.2022
Int.Class C09B 23/08
CCHEMISTRY; METALLURGY
09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES; MORDANTS; LAKES
23Methine or polymethine dyes, e.g. cyanine dyes
01characterised by the methine chain
02containing an odd number of CH groups
08more than three CH groups, e.g. polycarbocyanines
Appl.No PCT/EP2021/086202 Applicant BRACCO IMAGING SPA Inventor NAPOLITANO, Roberta
The present invention relates to the field of optical imaging. More particularly, it relates to a class of monoalkylated cyanine dyes with red to near-infrared (650-900 nm) emission characterized by pH responsiveness and to conjugates with biological ligands thereof. The invention also relates to the use of these compounds as optical diagnostic agents in imaging or therapy of solid tumors, to the methods for their preparation and to the compositions comprising them. The monoalkylated cyanine dyes have general formula (I) wherein R1 and R3 are independently selected from the group consisting of hydrogen, -SO3H, - COOH and -CONH-Y; and R2 and R4 are hydrogen, or both R1 together with R2 and R3 together with R4, respectively and with the atoms to which they are bonded, form two aryl rings, optionally substituted with from 1 to 4 -SO3H groups; R5 is an alkyl optionally substituted by a group selected from -SO3H, - COOH and -CONH2.
8.WO/2022/130197BIOMARKERS FOR DETECTING CANCER
WO 23.06.2022
Int.Class G01N 33/574
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
Appl.No PCT/IB2021/061690 Applicant UNIVERSITY OF CAPE TOWN Inventor LEANER, Virna Drucille
The invention provides a method, device, kit and computer- implemented method for diagnosing (and optionally also treating) cancer. The method for diagnosing cancer comprises the step of testing a blood sample from a subject suspected of having cancer for the presence of Ipo5 (Importin 5) and at least one other biomarker, the at least one other biomarker being selected from Ran (Ras-related nuclear protein) and KpnBl (Karyopherin beta 1). The blood sample may also be tested for additional biomarkers such as CRM1 (Cross- Reactive-Material-197), Kpna2 (Karyopherin alpha 2), CAS (Cellular apoptosis-susceptibility protein) and Transportin 1.
9.WO/2022/130332IN VITRO METHOD FOR FUNCTIONAL ASSESSMENT OF HAEMATOPOIETIC PROGENITORS
WO 23.06.2022
Int.Class G01N 33/50
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
Appl.No PCT/IB2021/061953 Applicant INSTITUTO DISTRITAL DE CIENCIA BIOTECNOLOGIA E INNOVACIÓN EN SALUD - IDCBIS Inventor PERDOMO ARCINIEGAS, Ana Maria Del Pilar
The present invention relates to an in vitro method for functional assessment of haematopoietic progenitors which makes it possible to assess the ability of haematopoietic progenitor cells (HPCs) to respond to growth factors and proliferate in products used for HPC transplantation, without need for cell culture. The disclosed method can be used for functional quantification of haematopoietic progenitors pre-transplantation and can also be used as a functional assay or functional prognostic biomarker for leukaemia or other tumours. The method could be used to separate HPCs from cell mixtures and collect them for use in cell therapy.
10.WO/2022/129702METHOD FOR DETERMINING WHETHER A SUBJECT IS AT RISK OF DEVELOPING A MUSCULOSKELETAL AND/OR CONNECTIVE TISSUE DISEASE
WO 23.06.2022
Int.Class G01N 33/68
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
Appl.No PCT/FI2021/050888 Applicant NIGHTINGALE OYJ Inventor JULKUNEN, Heli
A method for determining whether a subject is at risk of developing a musculoskeletal and/or connective tissue disease.