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IC:A61K39/12

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Analysis

1.WO/2022/129547NUCLEIC ACID VACCINES
WO 23.06.2022
Int.Class A61K 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
Appl.No PCT/EP2021/086528 Applicant UNIVERSITY OF COPENHAGEN Inventor BERTELSEN, Adam Frederik Sander
The present invention relates to modular nanoparticle-based compositions based on nucleic acids, such as DNA and RNA, which are particularly useful in prophylaxis and/or treatment of diseases and disorders.
2.WO/2022/130432NUCLEOTIDE SEQUENCE EXPRESSING AN EXTRACELLULAR VESICLE-ANCHORING PROTEIN FUSED WITH SARS-COV-2 ANTIGENS AND RELATED FUSION PROTEIN FOR USE AS VACCINE
WO 23.06.2022
Int.Class A61K 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
Appl.No PCT/IT2021/050405 Applicant ISTITUTO SUPERIORE DI SANITA' Inventor FEDERICO, Maurizio Paolo Maria
The present invention concerns a nucleotide sequence expressing an extracellular vesicle-anchoring protein fused with SARS-CoV-2 antigens and related fusion protein for use as vaccine, wherein said extracellular vesicle-anchoring protein is Nefmut or a truncated form of Nefmut.
3.WO/2022/129937IMMUNOGENIC PEPTIDE
WO 23.06.2022
Int.Class A61K 39/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
Appl.No PCT/GB2021/053351 Applicant UCL BUSINESS LTD Inventor REEVES, Matthew Bryan
P120670PCT 56 ABSTRACT Immunogenic peptide The invention provides a human herpesvirus immunogenic peptide comprising a novel antigenic domain (AD) of glycoprotein B, termed AD-6. The invention also provides a nucleic acid sequence encoding said immunogenic peptide and an inhibitor that binds to said 5 immunogenic peptide. Also provided are an immunogenic composition, a pharmaceutical composition and a vaccine comprising said immunogenic peptide, nucleic acid sequence or inhibitor, and methods of treating or preventing a human herpesvirus infection.
4.WO/2022/127236SINGLE-INJECTION VACCINE OF PROTEIN ANTIGEN AND PREPARATION METHOD THEREFOR
WO 23.06.2022
Int.Class A61K 9/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
Appl.No PCT/CN2021/119029 Applicant NANKAI UNIVERSITY Inventor ZHANG, Yongjun
Provided are a single-injection vaccine of a protein antigen and a preparation method therefor. The vaccine is composed of a protein antigen carrier coated with tannic acid-high-molecular polymer erodible coatings with different thicknesses on the surface thereof, and is characterized in that the erodible coatings on the surface of the protein antigen carrier are dissociated at a constant speed, and the protein antigen is released in a multi-pulse mode, so that the immune effect of multiple injections of conventional vaccines is achieved by single injection.
5.WO/2022/131832NOVEL VACCINE COMPOSITION FOR PREVENTION AND TREATMENT OF CORONAVIRUS
WO 23.06.2022
Int.Class A61K 39/215
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
215Coronaviridae, e.g. avian infectious bronchitis virus
Appl.No PCT/KR2021/019234 Applicant SL VAXIGEN, INC. Inventor SUNG, Young Chul
The present invention relates to a novel vaccine composition for the prevention and treatment of CoV, and more specifically provides a vaccine composition for the prevention and treatment of SARS CoV, comprising, as an active ingredient,: a first polynucleotide encoding a S protein of SARS CoV; and a second polynucleotide encoding a nucleocapsid protein (NP protein) of SARS CoV.
6.WO/2022/132777METHODS AND COMPOSITIONS FOR HYPERINFLAMMATORY SYNDROME AND THROMBOPHILIA ASSOCIATED WITH COVID-19
WO 23.06.2022
Int.Class A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
Appl.No PCT/US2021/063321 Applicant ROMEG THERAPEUTICS LLC Inventor MUNI, Indu
Methods and compositions for treating or preventing hyperinflammatory syndromes and thrombophilia associated with COVID-19 are provided.
7.WO/2022/132987METHOD OF MEASURING LEVELS OF NEUTRALIZING ANTIBODIES OF SARS-COV-2
WO 23.06.2022
Int.Class A61K 39/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
Appl.No PCT/US2021/063646 Applicant YOUHEALTH BIOTECH, LIMITED Inventor ZHANG, Kang
A method of assessing the immunity of a human subject against SARS-CoV-2 includes measuring the levels or concentrations of neutralizing antibodies of the subject in a bodily fluid of the subject that block the interaction between the receptor binding domain (RBD) of the viral spike protein of SARS-CoV-2 and the ACE2 cell surface receptor using a recombinant RBD or a portion thereof as an antigen to titrate the levels or concentrations of the neutralizing antibodies in the bodily fluid. A detection kit for detecting the levels or concentrations of neutralizing antibodies of the subject is also provided.
8.WO/2022/127946USE OF VACCINE COMPOSITIONS BASED ON SARS-COV-2 RECEPTOR BINDING DOMAIN IN DELIVERING PROTECTIVE IMMUNITY
WO 23.06.2022
Int.Class A61K 39/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
Appl.No PCT/CU2021/050014 Applicant INSTITUTO FINLAY DE VACUNAS Inventor VEREZ BENCOMO, Vicente Guillermo
The invention relates to the field of biotechnology and medicine. It describes the use of vaccine compositions based on the receptor binding domain of SARS-CoV-2 virus in the treatment of patients recovered from COVID-19 and in subjects vaccinated with vaccine platforms other than subunit vaccines, who fail to develop effective protective immunity or where immunity has decreased over time and a booster with the same vaccine used in primary vaccination is not recommended. Particularly, this use is described for vaccine compositions comprising a covalent conjugate of the receptor binding domain (RBD) and a carrier protein such as tetanus toxoid, diphtheria toxoid and diphtheria toxoid mutant CRM197, and vaccine compositions having the RBD as antigen, with or without the immunopotentiator outer membrane vesicles of serogroup B Neisseria meningitidis.
9.WO/2022/129881COMPOSITIONS AND METHODS
WO 23.06.2022
Int.Class A61K 39/09
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
09Streptococcus
Appl.No PCT/GB2021/053264 Applicant CHAIN BIOTECHNOLOGY LIMITED Inventor GREEN, Edward
A bacterium of the class Clostridia comprising a heterologous nucleic acid molecule encoding at least one antigen, wherein the bacterium is capable of expressing the antigen in an intracellular compartment of the bacterium during anaerobic cell growth, and wherein at least one antigen is an infectious agent antigen or a tumour antigen.
10.WO/2022/130196UNIVERSAL BACTERIOPHAGE T4 NANOPARTICLE PLATFORM TO DESIGN MULTIPLEX SARS-COV-2 VACCINE CANDIDATES BY CRISPR ENGINEERING
WO 23.06.2022
Int.Class C12N 7/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
7Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof
Appl.No PCT/IB2021/061688 Applicant THE CATHOLIC UNIVERSITY OF AMERICA Inventor RAO, Venigalla B.
The present disclosure relates to a system for and a method of incorporating SARS-CoV-2 genes and proteins into T4 phages. The present disclosure also relates to vaccine against SARS-CoV-2 containing recombinant T4 phages created using the method provided in the present disclosure.