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1.WO/2022/139132ANTIMICROBIAL COMPOSITION AND PREPARATION METHOD THEREFOR, AND PRODUCT THEREOF
WO 30.06.2022
Int.Class A61K 33/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
14Alkali metal chlorides; Alkaline earth metal chlorides
Appl.No PCT/KR2021/013739 Applicant IHN, Dong Chul Inventor IHN, Dong Chul
The present invention relates to an antimicrobial composition and a preparation method therefor, and a product thereof, and, more specifically, to an antimicrobial composition comprising: 50-60 wt% of purified water; 1-10 wt% of a mixture comprising, in a ratio of 1:1 (50 wt% : 50 wt%), sodium chloride and calcium chloride from among chlorides; 1-2 wt% of a mixture comprising, in a ratio of 1:1 (50 wt% : 50 wt%), a Pueraria thunbergiana extract and a Platycodon grandiflorus extract from among natural extracts; 5-10 wt% of a mixture comprising, in a ratio of 1:1 (50 wt% : 50 wt%), sodium carbonate and sodium bicarbonate from among carbonates; 10-15 wt% of a mixture comprising, in a ratio of 1:1 (50 wt% : 50 wt%), lactic acid and acetic acid from among organic acids, and salts thereof; and 5-10 wt% of a mixture (undiluted solution) comprising chloric-acid-based compounds, which are inorganic acids, and thus the antimicrobial composition ensures the safety of fermentation technology, and increases absorption rate and efficacy in the body so that an excellent antibacterial or antiviral immune enhancement effect can be obtained through the synergistic effect of physiological actions.
2.20220202747METHODS AND COMPOSITIONS FOR THE TREATMENT OF SHIGA TOXICOSIS
US 30.06.2022
Int.Class A61K 31/138
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines, e.g. amantadine
135having aromatic rings, e.g. methadone
138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
Appl.No 17698527 Applicant Board of Regents, The University of Texas System Inventor Somshuvra Mukhopadhyay

Methods for treating Shiga toxicosis, caused by infection with Shiga toxin bacteria, are provided. The methods include administering to a subject in need thereof an effective amount of one or more active agents selected from tamoxifen, 4-hydroxytamoxifen, endoxifen, toremifene, raloxifene, bazedoxifene, and pharmaceutically acceptable salts thereof. In some embodiments, the methods further include the administration of an antibiotic or a manganese compound to the subject. Pharmaceutical compositions for the treatment of Shiga toxicosis are also described.

3.WO/2022/133587GRAPHENE OXIDE-CATIONIC SILVER NANOCOMPOSITES AND THEIR USE AS BROAD-SPECTRUM ANTIMICROBIAL AGENTS
WO 30.06.2022
Int.Class A61K 33/38
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
24Heavy metals; Compounds thereof
38Silver; Compounds thereof
Appl.No PCT/CA2021/051849 Applicant ZENTEK LTD. Inventor HADDADI, Seyyedarash
The present invention relates to antimicrobial compositions comprising graphene-silver cation nanocomposites and uses for same as a broad-spectrum antimicrobial agent, and uses for same for treating microbial infections, including infections by antimicrobial resistant and/or multidrug resistant pathogens.
4.20220202852METHODS AND COMPOSITIONS OF AQUEOUS HYPOBROMOUS ACID FOR THE TREATMENT AND PREVENTION OF INFLAMMATORY CONDITIONS
US 30.06.2022
Int.Class A61K 33/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
Appl.No 17565348 Applicant Briotech, Inc. Inventor Daniel James Terry

The present disclosure provides methods and compositions of hypobromous acid for use in the treatment and prevention of inflammatory conditions, acute or chronic, of infectious or noninfectious origin, such as those attributable to hypersensitivity mechanisms or trauma in human subjects and animals. The disclosure in various embodiments provides compositions prepared at the time of need for such applications so as to contain pure hypobromous acid formed from stable precursor formulations containing oxidative chlorine in the form of hypochlorous acid, hypochlorite, or other forms of aqueous oxidative chlorine.

5.WO/2022/136181WEARABLE PET DEVICES WITH PASSIVE DIFFUSION OF SEMIOCHEMICAL COMPOSITIONS
WO 30.06.2022
Int.Class A01K 27/00
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
27Leads or collars, e.g. for dogs
Appl.No PCT/EP2021/086599 Applicant VIRBAC Inventor GIRARDIN, Aurélie
The present invention relates to portable pet devices capable of passively diffusing semiochemical compositions; these soothing devices allow animals to better manage stress-generating situations (situations of separation, withdrawal, transport, fear of noises, fireworks, etc.) and allow them to better adapt to the new situations.
6.WO/2022/133555SOLID PHARMACEUTICAL COMPOSITION CONTAINING VITAMIN D AND CALCIUM SALT, METHOD FOR TREATING OR PREVENTING CONDITIONS RELATED TO LOW INGESTION OF AND/OR HIGHER NEED FOR CALCIUM, USE OF THE SOLID PHARMACEUTICAL COMPOSITION, AND PHARMACEUTICAL PRODUCT OR SUPPLEMENT
WO 30.06.2022
Int.Class A61K 36/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
02Algae
04Rhodophycota or rhodophyta (red algae), e.g. Porphyra
Appl.No PCT/BR2020/050581 Applicant LITHOCÁLCIO INDÚSTRIA, COMÉRCIO, IMPORTAÇÃO, EXPORTAÇÃO E REPRESENTAÇÃO LTDA. Inventor PEREIRA DA SILVA, Rosana
The present invention describes a solid pharmaceutical composition including an external coating containing immediate-release vitamin D, and a matrix containing prolonged-release vitamin D and calcium salt, having the technical effect of improving calcium absorption, since it enables suitable concentrations of vitamin D in the blood throughout the release of calcium, which reduces the quantity of calcium excreted in faeces and improves the effectiveness of treatments for osteoporosis and other illnesses related to inadequate concentrations of calcium in the blood. The composition of the present invention can also be provided as mini-pills to facilitate administration by mouth, and also to modulate the quantity of calcium and vitamin D consumed by the patient/user. The present invention describes a solid pharmaceutical composition, a method for treating or preventing conditions related to low ingestion of and/or higher need for calcium, use of the solid pharmaceutical composition, and a pharmaceutical product or supplement. The present invention pertains to the field of medical preparations containing organic and inorganic active substances.
7.WO/2022/134245HEAT-CLEARING AND EXTERIOR SYNDROME-RELIEVING TRADITIONAL CHINESE MEDICINE COMPOSITION AND PREPARATION METHOD THEREFOR
WO 30.06.2022
Int.Class A61K 36/815
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
815Lycium (desert-thorn)
Appl.No PCT/CN2021/072050 Applicant HAINAN HULUWA PHARMACEUTICAL GROUP CO., LTD. Inventor LIU, Jingping
A heat-clearing and exterior syndrome-relieving traditional Chinese medicine composition and a preparation method therefor. The preparation method comprises the following steps: extracting volatile oils from Herba Pogostemonis and Herba Menthae to obtain the volatile oils, and retaining a distilled aqueous solution for use; soaking Flos Chrysanthemi and Fructus Forsythiae in an aqueous ethanol solution, performing ultrasound extraction and filtration, retaining the herb residue for use, and recovering ethanol from the filtrate to obtain a clear paste; taking Folium Isatidis, Radix Rehmanniae, Radix Cynanchi Atrati, Cortex Lycii, gypsum accounting for 75-85% of the amount thereof, and the herb residue, adding an aqueous ethanol solution for heat reflux extraction, mixing the extract solutions and filtering the mixture, after recovering ethanol from the filtrate, mixing the filtrate with the aqueous solution and the clear paste, and performing concentration to form a thick paste; taking the volatile oils to prepare a volatile oil inclusion compound; taking the remaining amount of gypsum and Radix Isatidis and crushing same into fine powder to obtain medicinal material fine powder, and sterilizing the medicinal material fine powder for later use; mixing the medicinal material fine powder with auxiliary materials, adding the thick paste, mixing uniformly, preparing particles, drying same, then adding the volatile oil inclusion compound, and mixing uniformly to obtain the composition. The present invention improves the contents of phillyrin and total flavonoids of Flos Chrysanthemi in the product, thereby improving the efficacy of the product.
8.20220202716EMPTY POROUS PARTICLES FOR USE IN TREATMENT, PREVENTION AND/OR POSTPONEMENT OF DEGENERATION OF NEURODEGENERATIVE DISEASES, NEURONS AND GLIA
US 30.06.2022
Int.Class A61K 9/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders
16Agglomerates; Granulates; Microbeadlets
Appl.No 17603566 Applicant Nanologica AB Inventor Adam Feiler

The present invention relates to empty porous particles having a diameter between 0.1 and 1000 μm, as measured by e.g. SEM, for use in diagnosis, prevention and/or postponement of neurodegenerative diseases, or for prevention and/or postponement of degeneration of neurons and glia. The invention also relates to a method of identifying biomarkers for use in diagnosis.

9.WO/2022/138923CERAMIDE SYNTHESIS PROMOTER
WO 30.06.2022
Int.Class A61K 35/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
02from inanimate materials
Appl.No PCT/JP2021/048218 Applicant A.I.SYSTEM PRODUCTS CORP. Inventor OKAJIMA Masahiro
A purpose of the present invention is to provide a novel ceramide synthesis promoter. The present invention relates to a ceramide synthesis promoter including alkaline ionized water obtained by electrolyzing an aqueous solution including a mineral salt containing silicon and phosphorus.
10.WO/2022/139418FATTY ACID-MODIFIED POLYMER NANOPARTICLES, AND USE THEREOF
WO 30.06.2022
Int.Class A61K 9/51
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
50Microcapsules
51Nanocapsules
Appl.No PCT/KR2021/019527 Applicant SUPERNOVA BIO CO., LTD. Inventor LEE, Kuen Yong
The present invention relates to fatty acid-modified polymer nanoparticles, and a use thereof. In the present invention, nanoparticles having embedded calcium carbonate crystals can be formed using a biocompatible polymer and an adipocyte-targeting ligand (a fatty acid) to minimize delivery to surrounding cells and tissues other than adipocytes and maximize the embedding of the nanoparticles into adipocytes. The nanoparticles according to the present invention can be produced as an injectable preparation, and can be applied to local lipolysis supplements or diet and beauty products that break down localized fat.