Processing

Please wait...

Settings

Settings

Goto Application

Offices all Languages Stemming false Single Family Member true Include NPL false
RSS feed can only be generated if you have a WIPO account

Save query

A private query is only visible to you when you are logged-in and can not be used in RSS feeds

Query Tree

Refine Options

Offices
All
Specify the language of your search keywords
Stemming reduces inflected words to their stem or root form.
For example the words fishing, fished,fish, and fisher are reduced to the root word,fish,
so a search for fisher returns all the different variations
Returns only one member of a family of patents
Include Non-Patent literature in results

Full Query

IC:C12P19/34

Side-by-side view shortcuts

General
Go to Search input
CTRL + SHIFT +
Go to Results (selected record)
CTRL + SHIFT +
Go to Detail (selected tab)
CTRL + SHIFT +
Go to Next page
CTRL +
Go to Previous page
CTRL +
Results (First, do 'Go to Results')
Go to Next record / image
/
Go to Previous record / image
/
Scroll Up
Page Up
Scroll Down
Page Down
Scroll to Top
CTRL + Home
Scroll to Bottom
CTRL + End
Detail (First, do 'Go to Detail')
Go to Next tab
Go to Previous tab

Analysis

1.WO/2022/170231MICROFLUIDIC CONCENTRATION AND BUFFER EXCHANGE APPARATUSES AND METHODS
WO 11.08.2022
Int.Class B01D 63/10
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
63Apparatus in general for separation processes using semi-permeable membranes
10Spiral-wound membrane modules
Appl.No PCT/US2022/015584 Applicant NUTCRACKER THERAPEUTICS, INC. Inventor ELDRIDGE, Benjamin
Microfluidic apparatuses including concentrators and buffer exchange regions that concentrate and exchange buffer. Also described are methods of passing a solution through a feed channel, filtering small molecules out of the feed channel by tangential flow filtration into a permeate channel adjacent to the first feed channel while maintaining a constant sheer rate relative to the membrane separating the feed channel from the permeate channel and exchanging buffer into the solution and concentrating the solution in a second region of the apparatus.
2.WO/2022/169846SYNTHETIC POLYNUCLEOTIDES AND METHODS FOR SELECTIVELY AMPLIFYING ALLELES
WO 11.08.2022
Int.Class C12P 19/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19Preparation of compounds containing saccharide radicals
26Preparation of nitrogen-containing carbohydrates
28N-glycosides
30Nucleotides
34Polynucleotides, e.g. nucleic acids, oligoribonucleotides
Appl.No PCT/US2022/014908 Applicant RHODX, INC. Inventor RODI, Charles
In alternative embodiments, provided are primer-based nucleic acid amplification methods capable of selecting against amplification or retrieval of a particular allele while not interfering with the amplification or retrieval of any alternative alleles or mutations at a particular nucleotide position within a target sequence, or in other words, provided are methods for selectively suppressing one allele while simultaneously amplifying any alternative allele, or, provided are methods for suppressing a wild type sequence while simultaneously amplifying a point mutation, including amplifying single nucleotide variants (SNVs), insertions and deletions. In alternative embodiments, a portion of the nucleic acid composition does not selectively suppress the amplification of a specific nucleic acid target sequence, thereby providing an internal control useful in determining the success of the amplification and in determining relative ratios of a specific nucleic target sequence to those encoding alternative allele(s) or mutations.
3.4039815SAMPLE PREPARATION FOR NUCLEIC ACID AMPLIFICATION
EP 10.08.2022
Int.Class C12P 19/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19Preparation of compounds containing saccharide radicals
26Preparation of nitrogen-containing carbohydrates
28N-glycosides
30Nucleotides
34Polynucleotides, e.g. nucleic acids, oligoribonucleotides
Appl.No 22165243 Applicant ILLUMINA CAMBRIDGE LTD Inventor FRASER LOUISE
The present invention relates to methods for preparing formalin-fixed paraffin-embedded samples for library amplification and subsequent nucleic acid (e.g. DNA) amplification, which methods are simpler to perform than existing methods.
4.20220243240ANALYSIS OF NUCLEIC ACIDS ASSOCIATED WITH SINGLE CELLS USING NUCLEIC ACID BARCODE
US 04.08.2022
Int.Class C12P 19/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19Preparation of compounds containing saccharide radicals
26Preparation of nitrogen-containing carbohydrates
28N-glycosides
30Nucleotides
34Polynucleotides, e.g. nucleic acids, oligoribonucleotides
Appl.No 17716617 Applicant Atreca, Inc. Inventor Yann Chong TAN

Provided herein are methods and compositions for analyzing nucleic acids associated with single cells using nucleic acid barcodes. According to some embodiments, a method for producing one or more polynucleotides of interest comprises: obtaining a plurality of RNAs associated with one or more samples, wherein the samples are obtained from one or more subjects, each RNA is associated with a single sample, and the RNAs associated with each sample are present in a separate reaction volume; adding an adapter molecule to the RNAs associated with each sample, wherein the adapter molecule is generated using an enzymatic reaction and comprises a universal priming sequence, a barcode sequence, and a binding site; and incorporating the barcode sequence into one or more polynucleotides associated with each sample, thereby producing the one or more polynucleotides of interest.

5.WO/2022/162027METHOD OF REDUCING THE IMMUNOSTIMULATORY PROPERTIES OF IN VITRO TRANSCRIBED RNA
WO 04.08.2022
Int.Class C12P 19/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19Preparation of compounds containing saccharide radicals
26Preparation of nitrogen-containing carbohydrates
28N-glycosides
30Nucleotides
34Polynucleotides, e.g. nucleic acids, oligoribonucleotides
Appl.No PCT/EP2022/051807 Applicant CUREVAC AG Inventor THRAN, Moritz
The present invention provides a method of reducing the immunostimulatory properties of an in vitro transcribed RNA by producing the in vitro transcribed RNA comprising a 3' terminal A nucleotide. Hereby, the circular DNA template used to generate the in vitro transcribed RNA has been linearized using a type IIS endonuclease. The invention further provides pharmaceutical compositions comprising the vitro transcribed RNA comprising a 3' terminal A nucleotide according to the invention for use in therapy.
6.WO/2022/159558SYSTEMS AND METHODS FOR TEMPLATE-FREE REACTION PREDICTIONS
WO 28.07.2022
Int.Class C12Q 1/68
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
Appl.No PCT/US2022/013083 Applicant KEBOTIX, INC. Inventor SHEBERLA, Dennis
The techniques described herein relate to methods and apparatus for determining a set of reactions to produce a target product. The method includes receiving the target product, executing a graph traversal thread, requesting, via the graph traversal thread, a first set of reactant predictions for the target product, executing a molecule expansion thread, determining, via the molecule expansion thread and a reactant prediction model, the first set of reactant predictions, and storing the first set of reactant predictions as at least part of the set of reactions.
7.WO/2022/156188METHOD FOR PRODUCING TARGET DNA SEQUENCE AND CLONING VECTOR
WO 28.07.2022
Int.Class C12N 15/63
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
Appl.No PCT/CN2021/111152 Applicant NANJING GENSCRIPT BIOTECH CO., LTD. Inventor YE, Lumeng
Provided is a method for producing a target DNA sequence and a cloning vector. The method includes the step of amplifying and extracting a DNA construct in a host cell, and a three-step thermostatic enzyme reaction step of protelomerase-IIS type restriction endonuclease and/or meganuclease-DNA exonuclease catalysis, wherein the construct is autonomously replicated and contains: (a) one or more IIS type restriction endonuclease and/or meganuclease recognition sequences; (b) the target DNA sequence; and (c) protelomerase recognition sequences at lateral wings of two ends of the target DNA sequence.
8.WO/2022/156117METHOD FOR MODIFYING DNA WITH GLYCOSIDASE AND OXYLAMINE COMPOUND
WO 28.07.2022
Int.Class C07H 21/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
21Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
04with deoxyribosyl as saccharide radical
Appl.No PCT/CN2021/097832 Applicant NANJING UNIVERSITY Inventor YU, Hanyang
Disclosed is a method for modifying DNA with glycosidase and an oxylamine compound, comprising the following steps: performing solid-phase synthesis of a DNA chain having a non-canonical base; reacting the DNA chain having the non-canonical base under the catalysis of glycosidase which selectively recognizes non-canonical bases to produce a DNA chain having an abasic site; reacting the DNA chain having the abasic site with the oxylamine compound to produce DNA modified with a chemical functional group. The method enables diversified site-specific DNA modification, studies the base structure-function relationship of functional DNA and construct more active functional DNA. The method is simple and easy to use and can reduce the cost and time of modification. The modified functional DNA has higher activity and can provide better tool molecules for biotechnologies and disease diagnosis.
9.114774411大片段DNA环化连接方法
CN 22.07.2022
Int.Class C12N 15/11
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
Appl.No 202210679408.0 Applicant 序康医疗科技(苏州)有限公司 Inventor 任军
本发明涉及一种大片段DNA环化连接方法及其在测序文库构建中的应用,和用于实现所述方法和应用的环化接头和试剂盒和由此形成的DNA分子和测序文库。
10.114774448一种功能性单链自组装RNA纳米颗粒的制备方法
CN 22.07.2022
Int.Class C12N 15/70
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
70Vectors or expression systems specially adapted for E. coli
Appl.No 202210386526.2 Applicant 浙江理工大学 Inventor 金伟波
本发明提供一种功能性单链自组装RNA纳米颗粒的制备方法,该方法利用生物合成的方法获得RNA纳米颗粒,其策略是利用RNAnano程序设计的单链自组装RNA纳米序列,然后将其编码的DNA序列构建成表达载体,导入到缺失RNaseⅢ的宿主中,经过宿主表达得到自组装RNA纳米颗粒。与外源蛋白质的原核表达相类似,单链自组装RNA纳米分子将在宿主体内通过转录合成、自组装折叠形成RNA纳米颗粒而不受RNA酶的降解,实现大量积累,实现功能性单链自组装RNA纳米颗粒的可持续、大规模的制备。