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Analysis

1 / 31,297
1.WO/2025/140077COMBINATION FOR DETECTING TARGET GENES AND USE THEREOF
WO - 03.07.2025
Int.Class C12Q 1/689
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6888for detection or identification of organisms
689for bacteria
 Appl.No PCT/CN2024/141311 Applicant SUZHOU PRECIGENOME LTD, CO; Inventor ZHANG, Xuan
Provided is a combination for specifically detecting P target genes. The combination comprises P pairs of primers used for amplifying P genes and P probes used for hybridizing the P genes. The P probes are respectively labelled with M different fluorescent groups having N concentrations; the types or concentrations of fluorescent groups carried by each probe among the P probes are different; and the P target genes and the fluorescent groups meet the following formula: 2≤P≤(MN+M)-X, M being a positive integer greater than or equal to 2, N ranging from 1 to 3, and X ranging from 0 to 19.
2.WO/2025/144712METHOD FOR AQUEOUS CONJUGATION OF SUBSTRATES USING DIELS-ALDER CHEMISTRY
WO - 03.07.2025
Int.Class C12Q 1/6806
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction assay
 Appl.No PCT/US2024/061289 Applicant LIFE TECHNOLOGIES CORPORATION Inventor LI, Dong
A method for conjugating oligonucleotides to bead supports includes adding 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-morpholinium to an aqueous suspension including bread supports having carboxy functional groups; adding amino-maleimide to the aqueous suspension; and adding diene modified oligonucleotide to the aqueous suspension.
3.WO/2025/140181METHOD FOR SIMULTANEOUSLY ANALYZING GENETIC INFORMATION AND EPIGENETIC INFORMATION
WO - 03.07.2025
Int.Class C12Q 1/6806
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction assay
 Appl.No PCT/CN2024/141792 Applicant AMOY DIAGNOSTICS CO., LTD. Inventor YU, Jiyan
The present invention relates to a method for preparing a double-stranded nucleic acid molecule, a method for preparing a DNA library, and a method for analyzing epigenetic information and/or genetic information. In addition, the present invention further relates to a double-stranded nucleic acid molecule and a DNA library respectively prepared by the methods.
4.WO/2025/140706LIVER CANCER TARGET, AND LIVER CANCER INHIBITION REAGENT AND USE THEREOF
WO - 03.07.2025
Int.Class A61K 45/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
 Appl.No PCT/CN2024/143789 Applicant SHANGHAI YIZHE BIOTECHNOLOGY CO., LTD. Inventor LI, Zhenyan
The present invention provides a liver cancer target, and a liver cancer inhibition reagent and a use thereof. According to the present invention, an important pathogenic factor EC-HBV-Fs of liver cancer is determined, the pathogenic factor EC-HBV-Fs can be used as a target to prepare a targeted regulation reagent, and is used for treating liver cancer and blocking a liver cancer process, or the pathogenic factor EC-HBV-Fs can be used as a target to screen for a reagent for targeted regulation. The present invention further provides a nucleic acid inhibitor for targeted regulation. The present invention further provides a target for liver cancer detection. The present invention provides a new way for clinical treatment and detection of liver cancer.
5.WO/2025/142491PRIMER SET AND NUCLEIC ACID AMPLIFICATION METHOD
WO - 03.07.2025
Int.Class C12Q 1/689
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6888for detection or identification of organisms
689for bacteria
 Appl.No PCT/JP2024/043841 Applicant ASAHI GROUP HOLDINGS, LTD. Inventor KURNIAWAN Yohanes Novi
The present invention provides a primer set specifically for the isothermal nucleic acid amplification of nucleic acids from obligate anaerobic bacteria or lactic acid bacteria. The present invention is: a primer set for detecting obligate anaerobic bacteria, said primer set comprising a forward primer including the base sequence represented by SEQ ID NO: 1 and a reverse primer including the base sequence represented by SEQ ID NO: 2; a primer set for detecting lactic acid bacteria, said primer set comprising a forward primer including the base sequence represented by SEQ ID NO: 3 and a reverse primer including the base sequence represented by SEQ ID NO: 4; a primer set for detecting lactococcus bacteria, said primer set comprising a forward primer including the base sequence represented by SEQ ID NO: 5 and a reverse primer including the base sequence represented by SEQ ID NO: 6; and a nucleic acid amplification method in which a RPA reaction is carried out using a test sample and one of the abovementioned primer sets to amplify a nucleic acid from the rRNA gene of obligate anaerobic bacteria or lactic acid bacteria contained in the test sample.
6.WO/2025/144021METHOD AND APPARATUS FOR EDITING DISPLAY OF DETECTION RESULTS OF PLURALITY OF BIOLOGICAL TARGET ANALYTES
WO - 03.07.2025
Int.Class G16B 45/00
GPHYSICS
16INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
45ICT specially adapted for bioinformatics-related data visualisation, e.g. displaying of maps or networks
 Appl.No PCT/KR2024/097149 Applicant SEEGENE, INC. Inventor JOO, Jae Hyung
The present invention provides technology for selectively editing the results of determining the presence/absence of a plurality of target nucleic acids using a detection reagent for a multiplex nucleic acid amplification reaction, wherein a plurality of target nucleic acids that can be amplified using the detection reagent are displayed, and the plurality of target nucleic acids can be edited so that the results of determining the presence/absence of some of the target nucleic acids are masked so as not to be displayed according to user selection.
7.WO/2025/140607QUANTITATIVE MEASUREMENT METHOD FOR NUCLEIC ACID IN NUCLEIC ACID-LIPID NANOPARTICLE COMPLEX
WO - 03.07.2025
Int.Class C12Q 1/6806
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction assay
 Appl.No PCT/CN2024/143317 Applicant BEIJING JITAI PHARMACEUTICAL TECHNOLOGY CO., LTD Inventor LEI, Jiani
A quantitative measurement method for a nucleic acid in a nucleic acid-lipid nanoparticle complex, sodium lauryl sulfate serving as a demulsifier. Said quantitative measurement method can accurately and quantitatively determine the effective nucleic acid concentration and the encapsulation rate.
8.WO/2025/140682NUCLEIC ACID MOLECULE FOR NUCLEIC ACID DETECTION, DETECTION PRODUCT, AND METHOD
WO - 03.07.2025
Int.Class C12Q 1/6806
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction assay
 Appl.No PCT/CN2024/143577 Applicant JIANGSU MICRODIAG BIOMEDICAL TECHNOLOGY CO., LTD. Inventor QU, Xiangyun
Provided is a nucleic acid molecule, which is formed by a first nucleic acid region labeled with a label being connected to a second nucleic acid region by means of a sensitization and connection region; the first nucleic acid region is a single-stranded nucleic acid to be cleaved; the second nucleic acid region comprises a stem-loop structure region and a specific nucleic acid region that binds to a target nucleic acid; the sensitization and connection region comprises a chemical bond, a ligand-receptor system, and a compound comprising a phosphate group as well as a hydroxyl group and/or an amino group; and the first nucleic acid region and the second nucleic acid region do not form a complementarily paired double-stranded structure region.
9.WO/2025/143577BIOMARKER FOR PREDICTING SYSTEMIC LUPUS ERYTHEMATOSUS FLARE
WO - 03.07.2025
Int.Class G01N 33/564
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
564for pre-existing immune complex or autoimmune disease
 Appl.No PCT/KR2024/018958 Applicant AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION Inventor KIM, Kyu-Tae
The present application relates to a biomarker composition for predicting systemic lupus erythematosus flare, comprising, as an active ingredient, a protein expressed in CD8 + T cells or a gene encoding same.
10.WO/2025/140967IMMUNOASSAY FOR DETECTION OF SPECIFIC NUCLEIC ACIDS, SUCH AS MRNA OR OTHER LARGE RNA MOLECULES
WO - 03.07.2025
Int.Class C12Q 1/6816
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6813Hybridisation assays
6816characterised by the detection means
 Appl.No PCT/EP2024/087826 Applicant SIEMENS HEALTHINEERS AG Inventor HUANG, Yiwei
The present invention relates to a method for detecting a target RNA polynucleotide by using a pool of targeted DNA catcher polynucleotides which generate stretches of RNA/DNA heterohybrids that can be detected with antibodies specific to said RNA/DNA heterohybrids. Further envisaged is a kit for detecting a specific target RNA polynucleotide comprising inter alia one or more DNA catcher polynucleotides complementary to at least a portion of the target RNA polynucleotide, a mature crRNA molecule which is specific for a target sequence on the target RNA polynucleotide and a catalytically-inactive crRNA-guided RNA-binding protein; as well as the use of these ingredients for the detection of the target RNA polynucleotide.
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