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Analysis

1.WO/2022/202043CELL CULTURE CONTAINER AND CELL CULTURE METHOD
WO 29.09.2022
Int.Class C12M 3/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
Appl.No PCT/JP2022/007072 Applicant TOYODA GOSEI CO., LTD. Inventor TAKI Seitaro
A cell culture container provided with a first container, a second container, and a culture membrane retained between the first container and the second container, in which each of the first container and the second container is provided with a first surface having a retention unit on which the culture membrane is retained, a second surface which faces the first surface, a first cell and a second cell which are located adjacent to each other in a second direction that is orthogonal to a first direction that extends from the first surface toward the second surface, a partitioning wall which partitions between the first cell and the second cell and extends from the first surface toward the second surface, a communication unit which is formed between the partitioning wall and the second surface and allows the first cell and the second cell to be communicated with each other, and a third surface which faces the partitioning wall in the second direction and zones the second cell in conjunction with the second surface, and in which an insertion port is formed.
2.WO/2022/202733CELL CULTURING SYSTEM
WO 29.09.2022
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/JP2022/012949 Applicant TERUMO KABUSHIKI KAISHA Inventor IGARASHI, Masatsugu
A cell culturing system (10) includes a processing unit (24) that performs culturing of cells, a reactor installation device (68) in which the processing unit (24) is capable of being installed, a connection circuit (26) that is connected to the processing unit (24), and a circuit control device (66) which the connection circuit (26) is capable of being attached to and detached from, and which is capable of carrying out supply of the cells and a culture medium from the connection circuit (26) to the processing unit (24), and carrying out collection of cultured cells from the processing unit (24) into the connection circuit (26). The processing unit (24) includes a plurality of bioreactors (30). The reactor installation device (68) is disposed separately with respect to the circuit control device (66).
3.WO/2022/203513APPARATUS AND PROCESS FOR CULTURING TISSUE
WO 29.09.2022
Int.Class C12M 3/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
Appl.No PCT/NL2022/050165 Applicant MEATABLE B.V. Inventor DEZFULI, Sina
An apparatus for culturing muscle tissue comprises a chamber extending from a first end to a second end; a first anchor located within the chamber at the first end; a second anchor located within the chamber at the second end; an inlet; and an outlet. The chamber can have an expanding or cylindrical cross-section from each of the first end and the second end to a point between the first end and the second end. The first and second anchors are three-dimensional.
4.20220306978CELL CAPTURE AND EXPANSION
US 29.09.2022
Int.Class C12M 1/12
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
12with sterilisation, filtration, or dialysis means
Appl.No 17702658 Applicant Terumo BCT, Inc. Inventor Mark E. Jones

Implementations are described that relate to methods and systems for growing cells in a hollow fiber bioreactor. In implementations, the cells may be exposed to a number of growth factors including a combination of recombinant growth factors. In other implementations, the cells may be grown in co-culture with other cells, e.g., hMSC's. In implementations, the cells may include CD34+ cells. A coated membrane includes a membrane having a first coating configured to promote cellular adhesion to the membrane and a second coating that includes a soluble protein moiety.

5.WO/2022/202044CELL CULTURE VESSEL AND CELL CULTURE METHOD
WO 29.09.2022
Int.Class C12M 3/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
Appl.No PCT/JP2022/007077 Applicant TOYODA GOSEI CO., LTD. Inventor TAKI Seitaro
Provided is a cell culture vessel including: an inner cylinder having an inner-cylinder one-end section, an inner-cylinder other-end section facing the inner-cylinder one-end section, a cylindrical inner-cylinder side wall connecting the inner-cylinder one-end section and the inner-cylinder other-end section, and an inner-cylinder recessed section formed as a notch in the inner-cylinder other-end section; a liquid stop pin that is detachably attached to the inner-cylinder recessed section to close the inner-cylinder recessed section; a culture membrane part that is disposed on the inner-cylinder one-end section and that closes an inner-cylinder opening formed in the inner-cylinder one-end section; and an outer cylinder that is detachably attached to the inner cylinder from the inner-cylinder one-end section side and that has an outer-cylinder one-end section, an outer-cylinder other-end section facing the outer-cylinder one-end section, and a cylindrical outer-cylinder side wall connecting the outer-cylinder one-end section and the outer-cylinder other-end section. In a state in which the outer cylinder is attached to the inner cylinder, the culture membrane part closes an outer-cylinder opening in the outer-cylinder other-end section.
6.WO/2022/202731CELL CULTURE SYSTEM
WO 29.09.2022
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/JP2022/012947 Applicant TERUMO KABUSHIKI KAISHA Inventor IGARASHI, Masatsugu
This cell culture system (10) comprises: a reactor (12); a distribution channel (16) through which a medium flows in and out of the reactor (12); a waste liquid channel (18) through which the medium is discharged from the distribution channel (16); and a waste liquid container (62) capable of storing the medium transported via the waste liquid channel (18). The waste liquid channel (18) has a temporary storage part (64) capable of temporarily storing the medium. The waste liquid container (62) is located below the temporary storage part (64) in the direction of gravity. The temporary storage part (64), which is located above the distribution channel (16) in the direction of gravity, temporarily stores the medium discharged from the distribution channel (16) and allows the medium to flow out toward the waste liquid container (62).
7.WO/2022/202911TEMPERATURE-RESPONSIVE POLYMER SURFACE TREATMENT AGENT
WO 29.09.2022
Int.Class C12M 3/04
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
04with means providing thin layers
Appl.No PCT/JP2022/013590 Applicant TOSOH CORPORATION Inventor JIDO Yumiko
Provided are: a temperature-responsive polymer surface treatment agent containing a temperature-responsive polymer and a cell-adhesive polymer including a monomer in which the HLB value (Griffin's method) with a monomer having a functional group exhibiting acidity is in the range of 0-5.0; and a temperature-responsive cell culture substrate in which cell adhesion and cell recovery by cooling treatment are achieved by coating a substrate with the temperature-responsive polymer surface treatment agent.
8.WO/2022/202732CELL CULTURING SYSTEM
WO 29.09.2022
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/JP2022/012948 Applicant TERUMO KABUSHIKI KAISHA Inventor IGARASHI, Masatsugu
The cell culturing system (10) is equipped with a plurality of processing units (24) that perform culturing of cells, a plurality of reactor installation devices (68) in which the plurality of processing units (24) are capable of being respectively installed, a plurality of connection circuits (26) connected respectively to the plurality of processing units (24), a plurality of circuit control devices (66) which the plurality of connection circuits (26) are capable of being respectively attached to and detached from, and a sensor device (70). The sensor device (70) is used in common with respect to the plurality of processing units (24), in order to measure components of the culture medium guided into the plurality of processing units (24). Each of the plurality of processing units (24) includes a plurality of bioreactors (30).
9.WO/2022/203800FILL LEVEL DETECTION
WO 29.09.2022
Int.Class G01F 23/24
GPHYSICS
01MEASURING; TESTING
FMEASURING VOLUME, VOLUME FLOW, MASS FLOW, OR LIQUID LEVEL; METERING BY VOLUME
23Indicating or measuring liquid level, or level of fluent solid material, e.g. indicating in terms of volume, indicating by means of an alarm
22by measurement of physical variables, other than linear dimensions, pressure, or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water
24by measuring variations of resistance of resistors due to contact with conductor fluid
Appl.No PCT/US2022/017666 Applicant COOK MEDICAL TECHNOLOGIES LLC Inventor CHAND, Tony
A device may include a flask for holding liquid. The flask may include liquid sensors for determining a fill level of the liquid in the flask. Control circuitry may be obtain readings from the sensors and determine the fill level of the flask by applying one or single- threshold conditions for elevated fill levels and a multiple-threshold condition when determining that the fill level of the liquid is at a bottom fill level.
10.WO/2022/203411FUNCTIONAL MEMBRANE AND MICROFLUIDIC CHIP COMPRISING SAME AND METHOD FOR MANUFACTURING SAME
WO 29.09.2022
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/KR2022/004103 Applicant UNIST(ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) Inventor KANG, Joo Hun
The present invention relates to a functional membrane, a microfluidic chip comprising same, and a method for manufacturing the microfluidic chip. The functional membrane according to an embodiment of the present invention comprises: a membrane having one or more pores; and a coating material on at least a surface of the membrane to cover the one or more pores.