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1.WO/2022/203228COMPOSITION FOR PREVENTION OR TREATMENT OF INFLAMMATORY DISEASES CAUSED BY ULTRAFINE PARTICULATE MATTER COMPRISING PORPHYRA TENERA EXTRACT AS ACTIVE INGREDIENT
WO 29.09.2022
Int.Class A23L 33/10
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
Appl.No PCT/KR2022/002932 Applicant INDUSTRY-ACADEMICCOOPERATION FOUNDATIONGYEONGSANGNATIONAL UNIVERSITY Inventor HEO, Ho Jin
The present invention relates to a composition for the prevention or treatment of inflammatory bowel diseases, inflammatory lung diseases or inflammatory cranial nerve diseases caused by ultrafine particulate matter, the composition comprising a Porphyra tenera extract as an active ingredient. The Porphyra tenera; P. tenera extract of the present invention is highly effective in preventing, ameliorating or treating inflammatory diseases caused by ultrafine particulate matter, and thus can be effectively used as a health functional food composition for the prevention or amelioration of inflammatory diseases caused by ultrafine particulate matter, a pharmaceutical composition for the prevention or treatment of inflammatory diseases caused by ultrafine particulate matter, or a cosmetic composition for the prevention or amelioration of inflammatory diseases caused by ultrafine particulate matter.
2.WO/2022/203543METHOD FOR REDUCING THE LEVELS OF EXPRESSION OF THE GENES LRNN3, GRAP, VAMP5
WO 29.09.2022
Int.Class A61K 36/21
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
Appl.No PCT/RU2022/000080 Applicant GORDEYCHUK, Vladimir Evgenevich Inventor POSPELOV, Vadim Igorevich
The invention relates to the field of gerontology, and more particularly to the possibility of acting on the expression profile of certain genes in human blood plasma which are associated with biological aging by administering an amaranth extract loaded into autologous exosomes, which makes it possible for this form of extract to be used as a protective agent against the effect of certain genetic factors in human blood plasma which are involved in the processes of biological aging of the body. The technical result of the claimed method is the possibility of reducing the levels of expression of the genes LRNN3, GRAP and VAMP5, the expression level of which rises as the biological age of the body increases, using autologous exosomes loaded with an amaranth extract. This technical result is achieved in that the claimed method includes consecutively carrying out the following steps: obtaining autologous exosomes; obtaining an amaranth extract (a commercial extract can be used); loading the obtained amaranth extract into the autologous exosomes; orally administering the loaded exosomes, diluted 1:10 in physiological solution, in an amount of 15 ml per 10 kg of body weight.
3.WO/2022/203303LACTOBACILLUS PLANTARUM GB104 STRAIN AND COMPOSITION COMPRISING SAME FOR PREVENTION OR TREATMENT OF CANCER
WO 29.09.2022
Int.Class A61K 35/747
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
74Bacteria
741Probiotics
744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
747Lactobacilli, e.g. L. acidophilus or L. brevis
Appl.No PCT/KR2022/003890 Applicant GI BIOME Inventor JANG, Myung Ho
The present invention relates to a Lactobacillus Plantarum GB104 strain (accession number: KCTC 14107BP) and a composition comprising same as active ingredient for prevention or treatment of cancer. The Lactobacillus plantarum GB104 strain according to the present invention increases production of INF-γ and granzyme B and activates immune cells such as cytotoxic T cells and NK cells, thereby being able to ultimately inhibit the formation and growth of tumors. Therefore, a composition comprising the Lactobacillus plantarum GB104 strain of the present invention as an active ingredient increases immune activity in the body and thus can be effectively utilized for treatment of cancer diseases and is highly industrially applicable.
4.WO/2022/204323NON-HALLUCINOGENIC ARIADNE ANALOGS FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS
WO 29.09.2022
Int.Class A61K 36/07
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
06Fungi, e.g. yeasts
07Basidiomycota, e.g. Cryptococcus
Appl.No PCT/US2022/021604 Applicant THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK Inventor CUNNINGHAM, Michael, J.
The present invention provides a compound having the structure (I) wherein R1 is (C2-C12 alkyl), - (alkenyl), - (alkynyl), - (cycloalkyl); R2 is H, halogen, -NO2, -CN, -CF3, -CF2H, -CH2OCH3, -CF2CH3, CF2OCH3, (alkyl), - (alkenyl), - (alkynyl), - (cycloalkyl), (cycloalkylalkyl), - (heteroalkyl), - (heterocycle), (heterocycloalkyl), - (aryl), - (heteroaryl), - (hydroxyalkyl), (haloalkyl), - (alkylaryl), -OH, -O- (alkyl), -O- (alkenyl), -O- (alkynyl), -O- (haloalkyl), -O- (aryl), -O- (heteroaryl), -OCF3, SH, -S- (alkyl), -S- (alkenyl), -S- (alkynyl), -S- (aryl), -S- (heteroaryl), -NH2, -NH- (alkyl), -NH- (alkenyl), -NH- (alkynyl), -N- (alkyl) 2, NH- (aryl), -NH- (heteroaryl), -CO2H, -CO2- (alkyl ), C (O) -NH2, -C (O) -NH- (alkyl), -C (O) -NH- (aryl), -SO2CH3 or Si (CH3) 3; R3 is -OCH3, -OCH2CH3, -F or -Cl; and R4 is -OCH3, -OCH2CH3 or -SCH3; wherein when R1 is -CH2CH3, R3 is -OCH3, and R4 is -OCH3, then R2 is other than H, -CH3, -CH2CH3, -CH2CH2CH3, -CH(CH3)2, CH2CH2CH2CH3, -CH2OH, -CH (OH) CH3, -OH, -OCH2CH3, -OCH2CH2CH3, OCH (CH3) 2, -SCH3, -SCH2CH3, -SCH2CH2CH3, -NO2, -NH2, -F, -Cl, -Br or - 1, or a pharmaceutically acceptable salt thereof.
5.20220305071COMPOSITION COMPRISING PRUNUS PERSICA EXTRACT
US 29.09.2022
Int.Class A61K 36/736
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
736Prunus, e.g. plum, cherry, peach, apricot or almond
Appl.No 17699348 Applicant OKCHUNDANG CO., LTD. Inventor Chul Jong JUNG

Disclosed herein is a composition comprising a Prunus persica extract for skin wrinkle reduction, anti-oxidation, skin regeneration, skin whitening, or wound healing. Exhibiting high effects of skin wrinkle reduction antioxidation, skin regeneration, skin whitening, or wound healing, the Prunus persica extract can find various applications in cosmetic products for skin wrinkle reduction, antioxidation, skin regeneration, skin whitening and medicinal topical formulations for wound healing.

6.202022104470Eine Formulierung als Elaeocarpus Ganitrus-Früchten mit antiallergischer und antihypersensibler Wirkung
DE 29.09.2022
Int.Class A61K 36/48
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
Appl.No 202022104470 Applicant Agarwal Ritesh Inventor

Formulierung von Elaeocarpus ganitrus-Früchten mit antiallergischer und antihypersensibler Wirkung, umfassend: Elaeocarpus ganitrus-Extrakt; und Akazie, wobei der Elaeocarpus ganitrus-Extrakt ein Lösungsmittelextrakt von Elaeocarpus ganitrus ist.

7.WO/2022/200334NUTRACEUTICAL COMPOSITION COMPRISING INULIN FOR TREATING AND PREVENTING OCULAR DISORDERS OR INTESTINAL MICROBIOTA IMBALANCE
WO 29.09.2022
Int.Class A61K 31/205
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
Appl.No PCT/EP2022/057466 Applicant OPHTALMIS Inventor CLARET, Martine
The present invention relates to a nutraceutical composition comprising inulin and a Chilean wineberry extract, and also other ingredients such as amino acids, vitamins and/or trace elements, in particular for the use thereof in preventing and/or treating ocular pathological conditions and/or in preventing and/or treating intestinal microbiota imbalances.
8.WO/2022/203334COMPOSITION FOR PREVENTING OR TREATING BRAIN CANCER
WO 29.09.2022
Int.Class A61K 31/225
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
215of carboxylic acids
22of acyclic acids, e.g. pravastatin
225Polycarboxylic acids
Appl.No PCT/KR2022/003949 Applicant INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY Inventor KANG, Seok-Gu
The present invention relates to a composition capable of effectively preventing, ameliorating, or treating cancer, particularly brain cancer, by using (-)-(2R,3R)-1,4-O-diferuloylsecoisolariciresinol (DFS) and a pharmaceutically acceptable salt thereof.
9.20220304976Method of simultaneously treating viral disease caused coronavirus, its variants and mutants using a pharmaceutical micronutrient composition
US 29.09.2022
Int.Class A61K 31/352
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
Appl.No 17728769 Applicant MATTHIAS W RATH Inventor Aleksandra Niedzwiecki

A method of preventing, inhibiting and treating a mammal suffering from viral infections using a pharmaceutical micronutrient composition including mixture D is disclosed. The middle east respiratory syndrome-related coronavirus and severe acute respiratory syndrome-related coronavirus as well as their variants and mutants affecting mammals and causing infection are successfully treated using mixture D. Mixture D contains key micronutrients such as an ascorbate, N-acetylcysteine, theaflavins, resveratrol, cruciferous plant extracts, curcumin, quercetin, naringenin, and baicalin and a combination thereof. Mixture D and seemed to have beneficial effects to prevent and treat diseases where viruses use the angiotensin converting enzyme 2 (ACE2) receptor on the surface of epithelial cells, endothelial cells and other cell types for viral entry.

10.20220305069A PREPARATION METHOD OF ANTRODIA CINNAMOMEA WATER-INSOLUBLE DIETARY FIBER
US 29.09.2022
Int.Class A61K 36/07
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
06Fungi, e.g. yeasts
07Basidiomycota, e.g. Cryptococcus
Appl.No 17431145 Applicant UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGY Inventor LIANZHONG AI

A preparation method of Antrodia cinnamomea water-insoluble dietary fiber. After ethanol and water extraction, Antrodia cinnamomea wastes are dried and superfine-comminuted to obtain Antrodia cinnamomea waste powder. The waste powder treated with NaOH solution containing NaBH4 is extracted it twice to obtain two extracts. The two extracts are combined and an appropriate amount of glacial acetic acid are added for neutralization. The extracts are centrifugalized and precipitate is collected. After washing the precipitate with ultrapure water, the precipitate is dissolved with LiCl-DMSO. The precipitate that is insoluble in the LiCl-DMSO solution is dialyzed and freeze-dried to obtain the water-insoluble dietary fiber component ACA-IDK of Antrodia cinnamomea. The LiCl-DMSO solution is subjected to ethanol/DMSO fractional precipitation, and then the precipitate is collected and dialyzed. The water-insoluble dietary fiber component ACA-DK of Antrodia cinnamomea is obtained after freeze-drying.