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1.WO/2022/010206QUARANTINE SYSTEM FOR HIGH-RISK INFECTIOUS DISEASE USING ISOTHERMAL AMPLIFICATION-BASED MOLECULAR DIAGNOSTICS
WO 13.01.2022
Int.Class C12Q 1/70
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
70involving virus or bacteriophage
Appl.No PCT/KR2021/008506 Applicant SEASUN BIOMATERIALS Inventor PARK, Sungmin
The present invention relates to a COVID-19 quarantine system using isothermal amplification-based molecular diagnostics for detecting SARS-CoV-2, and in particular, to a quarantine system in an airport, a port, a massive rally, or a superspreader area. According to the present invention, it is possible to quickly and accurately test COVID-19 infection on a large scale, and thus the present invention is effective for the quarantining of mass service facilities, such as airports, ports, and gymnasiums.
2.20220010389PRIMER SET FOR DETECTING SARS-COV-2, METHOD FOR TESTING SARS-COV-2, AND REAGENT AND KIT OF TESTING SARS-COV-2
US 13.01.2022
Int.Class C12Q 1/70
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
70involving virus or bacteriophage
Appl.No 17489049 Applicant NAGASAKI UNIVERSITY Inventor Jiro YASUDA

One embodiment according to the present invention relates to a primer set for detecting SARS-CoV-2, the set comprising a plurality of LAMP primers targeting one or more open reading frame (ORF) regions in a SARS-CoV-2 genome, wherein the one or more ORF regions are selected from the group consisting of Orf1b, OrfM, OrfN, and OrfS; and a technique relating to use of this primer set.

3.WO/2022/011215METHOD AND SYSTEM FOR SALIVA TESTING FOR VIRUS INCLUDING COVID-19
WO 13.01.2022
Int.Class C12Q 1/70
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
70involving virus or bacteriophage
Appl.No PCT/US2021/041016 Applicant THE ROCKEFELLER UNIVERSITY Inventor DARNELL, Robert B.
The present invention provides methods for rapid and efficient isolation and characterization of nucleic acid, particularly RNA, from small volume and self-collected samples, particularly saliva samples, to determine the presence or absence of infectious agent RNA, particularly viral RNA, particularly infectious viral RNA, particularly coronavirus. The invention provides methods for isolation and evaluation of infectious agent RNA from saliva samples, particularly viral agents, particularly coronavirus. The invention further provides methods and strategies for pooling samples and RNA to determine the presence or absence of infectious agent RNA, particularly viral RNA, particularly infectious viral RNA, particularly coronavirus, with regard to large numbers of samples at one time and in a single pooled test format.
4.WO/2022/009191DETECTING AND QUANTIFYING A VIRAL TARGET NUCLEIC ACID SEQUENCE
WO 13.01.2022
Int.Class C12Q 1/6806
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction assay
Appl.No PCT/IL2020/050761 Applicant BAR-ILAN UNIVERSITY Inventor DANIELLI, Amos
Oligonucleotide probes for detecting target nucleic acid sequences are disclosed.
5.20220002823INFECTIOUS DISEASE SCREENING DEVICE
US 06.01.2022
Int.Class C12Q 1/70
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
70involving virus or bacteriophage
Appl.No 17466906 Applicant SHAHEEN INNOVATIONS HOLDING LIMITED Inventor Imad Lahoud

A disease screening device (100) comprising a substrate (101) and a sonication chamber (102) formed on the substrate (101). The sonication chamber (102) is provided with an ultrasonic transducer (105) which generates ultrasonic waves to lyse cells in a sample fluid within the sonication chamber (102). The device (100) comprises a reagent chamber (111) formed on the substrate (101) for receiving a liquid PCR reagent. The device (100) comprises a controller (23) which controls the ultrasonic transducer (105) and a heating arrangement (128) which is provided on the substrate (101). The device (100) further comprises a detection apparatus which detects the presence of an infectious disease, such as COVID-19 disease.

6.WO/2022/006520ELECTROCHEMICAL BIOSENSORS FOR RAPID AND SENSITIVE DETECTION OF PATHOGENS AND PATHOGENIC BIOMARKERS
WO 06.01.2022
Int.Class C12Q 1/70
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
70involving virus or bacteriophage
Appl.No PCT/US2021/040302 Applicant CARNEGIE MELLON UNIVERSITY Inventor PANAT, Rahul
A method of preparing a functionalized electrode array is provided. The method includes depositing a conductive material onto the surface of a substrate by droplet-based printing of particles comprising an electrically-conductive material. The surface of the conductive material is functionalized with a binding reagent that binds to an analyte. A three-dimensional electrode array and microfluidic test device are also provided.
7.WO/2022/006536CRISPR-CAS-BASED DETECTION OF SARS-COV-2 USING RECOMBINASE POLYMERASE AMPLIFICATION
WO 06.01.2022
Int.Class C12Q 1/6888
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6888for detection or identification of organisms
Appl.No PCT/US2021/040338 Applicant THE REGENTS OF THE UNIVERSITY OF CALIFORNIA Inventor CHIU, Charles
The disclosure provides for CRTSPR-Cas-based detection of SARS-CoV-2 using recombinase polymerase amplification, and uses thereof.
8.WO/2022/003192AGENTS AND METHOD FOR ENRICHING OR DEPLETING AND FOR DETECTING CORONA VIRUSES
WO 06.01.2022
Int.Class G01N 33/569
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
569for microorganisms, e.g. protozoa, bacteria, viruses
Appl.No PCT/EP2021/068414 Applicant LEIBNIZ-INSTITUT FÜR PHOTONISCHE TECHNOLOGIEN E.V. Inventor POPP, Jürgen
The invention relates to agents and methods for enriching or depleting and for detecting corona viruses.
9.20220001014COMPOSITIONS AND METHODS FOR INDUCING BIOLOGICAL MIMICRY IN A MAMMAL FOR THE PREVENTION AND/OR TREATMENT OF COVID-19 AND OTHER DISEASES
US 06.01.2022
Int.Class A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
Appl.No 17366007 Applicant Lida Ghaderi Inventor Lida Ghaderi

The present invention is directed to compositions and methods for inducing artificial biological mimicry in a mammal to mimic the favorable immune advantages present in a bat in another mammal, particularly a human subject, and thereby prevent and/or treat COVID-19 and other diseases by administering to the subject a combination of active agents comprising two or more active agents comprising an inhibitor of inflammasome NLRP3, an inhibitor of one or more priming or activation signals of inflammasome NLRP3, and/or an activator of the inhibitor of one or more priming or activation signals of inflammasome NLRP3 alone or in combination with one or more modulators of Kallikrein-Kinin System (KKS) dysregulation, one or more modulators of Renin Aldosterone Angiotensin System (RAAS) dysregulation, one or more modulators of protease dysregulation, and/or one or more modulators of cytokine dysregulation. Pharmaceutical compositions, methods of treatment, methods of genetic testing, and packaged kits are provided.

10.WO/2022/000152RAPID PCR-BASED VIRUS DETECTION METHOD, AND KITS THEREFOR
WO 06.01.2022
Int.Class C12Q 1/70
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
70involving virus or bacteriophage
Appl.No PCT/CN2020/098691 Applicant JIANGSU COWIN BIOTECH CO., LTD Inventor WANG, Chunxiang
Provided is a virus preservation solution, an ucleic acid amplification reaction preparation (which can be in a lyophilized powder), a qPCR-based method to detect virus by nucleic acid amplification, and a PCR kit. The virus preservation solution can preserve a viral sample and prevent RNA degradation at room temperature for an extended period of time. The sample solution can be directly combined with the nucleic acid amplification reaction preparation without any viral nucleic acid extraction step for qPCR amplification for rapid and high-sensitivity virus detection.