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IC:C12M AND EN_ALLTXT:(coronavirus OR coronaviruses OR coronaviridae OR coronavirinae OR orthocoronavirus OR orthocoronaviruses OR orthocoronaviridae OR orthocoronavirinae OR betacoronavirus OR betacoronaviruses OR betacoronaviridae OR betacoronavirinae OR sarbecovirus OR sarbecoviruses OR sarbecoviridae OR sarbecovirinae OR "severe acute respiratory syndrome" OR sars OR "2019 ncov" OR covid)

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Analysis

1.3116216SYSTEM FOR IDENTIFYING SEVERE ACUTE RESPIRATORY SYNDROME CORONA VIRUS 2 (SARS-COV-2) RIBONUCLEIC ACID (RNA) AND METHOD OF IDENTIFYING SEVERE ACUTE RESPIRATORY SYNDROME CORONA VIRUS 2 (SARS-COV-2) RIBONUCLEIC ACID (RNA)
CA 29.10.2021
Int.Class C12Q 1/70
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
70involving virus or bacteriophage
Appl.No 3116216 Applicant TELEFLEX MEDICAL INCORPORATED Inventor

A system for detecting the presence of Severe Acute Respiratory Syndrome
Coronavirus
2 (SARS-CoV-2) in a biological sample includes a sampling device, a lysing
chamber, a NASBA
fluidic network, and an analytical instrument. The sampling device is
configured to contain a
sample containing a pathogen target sequence for SARS-CoV-2. The lysing
chamber is
configured to be in fluid communication with the sampling device to receive
the sample. The is
lysing chamber is configured to lyse the sample into a lysate. The NASBA
fluidic network is
configured to be in fluid communication with the lysing chamber to receive the
lysate. The
NASBA fluidic network includes an enzyme, a forward primer, and a reverse
primer for
amplifying a predetermined genetic sequence in the pathogen target sequence
contained within
the lysate. The forward primer has the oligonucleotide sequence selected from
the group
consisting of SEQ ID NO: 1, SEQ ID NO: 5, SEQ ID NO: 9, SEQ ID NO: 13, and SEQ
ID NO:
17. The reverse primer has the oligonucleotide sequence selected from the
group consisting of
SEQ ID NO: 2, SEQ ID NO: 6, SEQ ID NO: 10, SEQ ID NO: 14, and SEQ ID NO: 18. A

molecular beacon is configured to attach to the pathogen target sequence. The
beacon has the
oligonucleotide sequence selected from the group consisting of SEQ ID NO: 3,
SEQ ID NO: 7,
SEQ ID NO: 11, SEQ ID NO: 15, and SEQ ID NO: 19 and a fluorophore. The
analytical
instrument is configured to excite the beacon when the molecular beacon is
attached to the
pathogen target sequence to signal a presence of the pathogen target sequence.
A method for detecting the presence of Severe Acute Respiratory Syndrome
Coronavirus
2 (SARS-CoV-2) in a biological sample includes the steps of lysing the
biological sample to form
a lysate and generating an amplified lysate by performing a nucleic acid
sequence-based (NASBA)
amplification for a target nucleic acid sequence in the lysate in the presence
of: a forward primer
having the oligonucleotide sequence selected from the group consisting of SEQ
ID NO: 1, SEQ
ID NO: 5, SEQ ID NO: 9, SEQ ID NO: 13, and SEQ ID NO: 17; a reverse primer
having the

oligonucleotide sequence selected from the group consisting of SEQ ID NO: 2,
SEQ ID NO: 6,
SEQ ID NO: 10, SEQ ID NO: 14, and SEQ ID NO: 18; and a molecular beacon having
the
oligonucleotide sequence selected from the group consisting of SEQ ID NO: 3,
SEQ ID NO: 7,
SEQ ID NO: 11, SEQ ID NO: 15, and SEQ ID NO: 19 and a fluorophore. The
amplified lysate is
exposed to an excitation source. A fluorescence of the fluorophore is detected
in the amplified
lysate exposed to the excitation source. The SARS-CoV-2 is determined to be
present in the
biological sample in response to detecting the fluorescence of the
fluorophore.

2.20080254440Anti-Sars Virus Antibody, Hybridoma Producing the Antibody and Immunoassay Reagent Using the Antibody
US 16.10.2008
Int.Class C12Q 1/70
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
70involving virus or bacteriophage
Appl.No 10577310 Applicant UCHIDA YOSHIAKI Inventor Uchida Yoshiaki

A monoclonal antibody which specifically recognizes SARS virus is provided, and an immunoassay, immunoassay reagent and immunoassay device for detecting the SARS virus using the monoclonal antibody are disclosed. The monoclonal antibody according to the present invention is a monoclonal antibody against a nucleoprotein of a corona virus causing severe acute respiratory syndrome (SARS).

3.3098079APPARATUS AND METHOD FOR POINT-OF-CARE, RAPID, FIELD-DEPLOYABLE DIAGNOSTIC TESTING OF COVID-19, VIRUSES, ANTIBODIES AND MARKERS - AUTOLAB 20
CA 19.03.2021
Int.Class G01N 21/64
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
Appl.No 3098079 Applicant AUTONOMOUS MEDICAL DEVICES INC. Inventor

An automated system communicated to a remote server for diagnostically field
testing a
sample taken from a patient using an automated portable handheld instrument to

determine the presence of Covid-19 and/or antibodies thereto includes
microfluidic
circuits defined in a rotatable disk for performing a bioassay using a
microarray to
generate an electrical signal indicative of a bioassay measurement; the
microarray
operationally positioned in the microfluidic circuit; one or more lasers; one
or more
positionable valves in the microfluidic circuit; and a backbone unit for
rotating the disk
according to a protocol to perform the bioassay, for controlling the lasers to
selectively
open the positionable valves in the microfluidic disk, for operating the
microarray to
generate a digital image as a bioassay measurement; for communicating the
bioassay
measurement to the remote server, and for associating the performed bioassay
and its
corresponding bioassay measurement to the patient.

4.20070042350Methods and compositions for detecting sars virus and other infectious agents
US 22.02.2007
Int.Class C12Q 1/70
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
70involving virus or bacteriophage
Appl.No 10564378 Applicant LI ZE Inventor Li Ze

This invention relates generally to the field of virus detection. In particular, the invention provides chips, probes, primers, kits and methods for amplifying and detecting SARS-CoV nucleotides sequence. The clinical and other uses of the present chips, probes, primers, kits and methods are also contemplated.

5.WO/2021/202066METHOD AND SYSTEM FOR PROCESSING GENETIC DATA
WO 07.10.2021
Int.Class C12M 1/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
Appl.No PCT/US2021/021551 Applicant ALIBABA GROUP HOLDING LIMITED Inventor GU, Fei
Processing genetic data is disclosed including inputting data, the data corresponding to source data for gene sequencing on a sample, receiving a selected data processing technique, performing, using the selected data processing technique, gene sequencing processing on the inputted data based on the pathogen genome of a predetermined pathogen to obtain a data processing result, the data processing result indicating whether the sample includes the predetermined pathogen, and presenting the data processing result.
6.WO/2021/097193DEVICE FOR DIGITAL READ OF LATERAL FLOW ASSAY
WO 20.05.2021
Int.Class G01N 21/84
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
84Systems specially adapted for particular applications
Appl.No PCT/US2020/060390 Applicant SCHUBERT, Axel Inventor SCHUBERT, Axel
A device for receiving a digital reader and a lateral flow assay (LFA) cartridge and systems incorporating the same are provided. Aspects of the device include a body having a frame configured to receive the digital reader and a base plate having one or more LFA cartridge receiving positions for positioning one or more LFA cartridges at a fixed orientation relative to a planar space defined by the frame. Also provided are methods for using the device to read a result indicative of the presence or absence of an analyte in a sample.
7.WO/2021/250274DEVICE AND METHOD FOR CAPTURING AND ANALYSING AIRBORNE ORGANISMS
WO 16.12.2021
Int.Class C12Q 1/70
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
70involving virus or bacteriophage
Appl.No PCT/EP2021/065932 Applicant CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) Inventor ALCAMI PERTEJO, Antonio
The present invention refers to a device comprising polytetrafluorethylene (PTFE) filters and the use of the same for collecting, detecting and identifying organisms present in air ecosystems. The invention also provides a method suitable for the capture, detection and identification of whole airborne biological particles, including viruses and other important air pathogens, which involves the use of the device. This method allows toperform organism, preferably viral, metagenomics to sequence all DNA and RNA organisms captured in the filters. This methodology may be used to detect, for instance, SARS-CoV2 particles in air samples.
8.WO/2021/236488VIRAL SAMPLE COLLECTION
WO 25.11.2021
Int.Class A61B 17/43
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
17Surgical instruments, devices or methods, e.g. tourniquets
42Gynaecological or obstetrical instruments or methods
425for reproduction or fertilisation
43for artificial insemination
Appl.No PCT/US2021/032698 Applicant THOMAS JEFFERSON UNIVERSITY Inventor KEANE, William Martin
The present invention includes a method of obtaining a biological sample from the nose, nasal cavities, nasal pharynx, oral mucosa, or saliva of a subject to be used for detection of a virus (e.g., a SARS-CoV-2 virus), and kits for performing the method.
9.112760210Novel coronavirus integrated nucleic acid rapid detection card box
CN 07.05.2021
Int.Class C12M 1/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
Appl.No 202110155992.5 Applicant HANGZHOU SUIZENG BIOTECHNOLOGY CO., LTD. Inventor ZHAO HUAI
The invention discloses a novel coronavirus integrated nucleic acid rapid detection card box. The novel coronavirus integrated nucleic acid rapid detection card box comprises a box body with a box cover at the top, wherein a cracking cavity with a cracking liquid, a first cleaning cavity with a first cleaning liquid and a second cleaning cavity with a second cleaning liquid are sequentially arranged in the box body from top to bottom, the cracking cavity communicates with the box cover, and the second cleaning cavity communicates with a reaction cavity arranged at the bottom of the outer side of the box body; plungers with plunger hole directions perpendicular to the connecting direction are respectively arranged in the connecting sections of every two of the cracking cavity, the first cleaning cavity, the second cleaning cavity and the reaction cavity, and hydrophobic liquid sealing materials are arranged in plunger holes of the plungers; an amplification reaction liquid and a novel coronavirus detection primer and probe combination are arranged in the reaction cavity; and magnetic beads capable of penetrating through the plunger holes of the plungers are arranged in the cracking cavity. The novel coronavirus integrated nucleic acid rapid detection card box disclosed by the invention can integrally perform nucleic acid extraction and PCR amplification on novel coronaviruses under the condition of relatively low cost, and further can directly perform data collection and analysis required by optical detection.
10.WO/2021/252671FLOW CELL SYSTEMS AND DEVICES
WO 16.12.2021
Int.Class C12Q 1/6837
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6813Hybridisation assays
6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
6837using probe arrays or probe chips
Appl.No PCT/US2021/036670 Applicant ELEMENT BIOSCIENCES, INC. Inventor GUO, Minghao
Flow cell devices, cartridges, and systems are described that provide reduced manufacturing complexity, lowered consumable costs, and flexible system throughput for nucleic acid sequencing and other chemical or biological analysis applications. The flow cell device can include a capillary flow cell device or a microfluidic flow cell device.