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1. WO2021147236 - USE OF SUBSTITUTED AMINOPROPIONATE COMPOUND IN TREATMENT OF SARS-COV-2 INFECTIONS

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Publication Number WO/2021/147236
Publication Date 29.07.2021
International Application No. PCT/CN2020/097421
International Filing Date 22.06.2020
IPC
A61K 31/675 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
66Phosphorus compounds
675having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
A61P 31/14 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
A61P 11/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
CPC
A61K 31/675
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
66Phosphorus compounds
675having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
A61K 31/685
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
66Phosphorus compounds
683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
685one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 31/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
C07F 9/6561
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
9Compounds containing elements of Groups 5 or 15 of the Periodic System
02Phosphorus compounds
547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
6561containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
Applicants
  • 中国人民解放军军事科学院军事医学研究院 ACADEMY OF MILITARY MEDICAL SCIENCES [CN]/[CN]
Inventors
  • 钟武 ZHONG, Wu
  • 曹瑞源 CAO, Ruiyuan
  • 肖庚富 XIAO, Gengfu
  • 胡志红 HU, Zhihong
  • 王曼丽 WANG, Manli
  • 张磊砢 ZHANG, Leike
  • 李薇 LI, Wei
  • 李月香 LI, Yuexiang
  • 赵磊 ZHAO, Lei
  • 樊士勇 FAN, Shiyong
  • 李松 LI, Song
Agents
  • 中国国际贸易促进委员会专利商标事务所 CCPIT PATENT AND TRADEMARK LAW OFFICE
Priority Data
202010071087.721.01.2020CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) USE OF SUBSTITUTED AMINOPROPIONATE COMPOUND IN TREATMENT OF SARS-COV-2 INFECTIONS
(FR) UTILISATION D'UN COMPOSÉ D'AMINOPROPIONATE SUBSTITUÉ DANS LE TRAITEMENT D'INFECTIONS PROVOQUÉES PAR LE SARS-COV-2
(ZH) 取代氨基丙酸酯类化合物在治疗SARS-CoV-2感染中的应用
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Abstract
(EN) The present invention relates to a substituted aminopropionate compound as represented by formula I, and a pharmaceutically acceptable salt thereof and/or a solvate thereof and/or a hydrate thereof, and a pharmaceutical composition containing the compound, wherein same are used for treating diseases or infections caused by SARS-CoV-2.
(FR) La présente invention concerne un composé d'aminopropionate substitué représenté par la formule I, et un sel pharmaceutiquement acceptable de celui-ci et/ou un solvate de celui-ci et/ou un hydrate de celui-ci, et une composition pharmaceutique contenant le composé, ceux-ci étant utilisés pour traiter des maladies ou des infections provoquées par le SARS-CoV-2.
(ZH) 本申请涉及式I所示取代氨基丙酸酯类化合物，及其药学上可接受的盐和/或其溶剂化物和/或其水合物，及含有此化合物的药物组合物，用于治疗SARS-CoV-2引起的疾病或感染。
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