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1. WO2019027941 - CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF

Publication Number WO/2019/027941
Publication Date 07.02.2019
International Application No. PCT/US2018/044465
International Filing Date 31.07.2018
IPC
C07C 237/20 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
237Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
02having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
20the carbon skeleton containing six-membered aromatic rings
C07C 275/18 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
275Derivatives of urea, i.e. compounds containing any of the groups the nitrogen atoms not being part of nitro or nitroso groups
04having nitrogen atoms of urea groups bound to acyclic carbon atoms
18of a saturated carbon skeleton containing rings
C07C 307/02 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
307Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
02Monoamides of sulfuric acids or esters thereof, e.g. sulfamic acids
C07C 333/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
333Derivatives of thiocarbamic acids, i.e. compounds containing any of the groups the nitrogen atom not being part of nitro or nitroso groups
02Monothiocarbamic acids; Derivatives thereof
04having nitrogen atoms of thiocarbamic groups bound to hydrogen atoms or to acyclic carbon atoms
A61K 31/165 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
A61K 31/17 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
17having the group N-C(O)-N or N-C(S)-N, e.g. urea, thiourea, carmustine
CPC
A61K 31/165
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
A61K 31/17
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
17having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
A61K 31/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
18Sulfonamides
A61K 31/27
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
27of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
A61K 31/325
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
Applicants
  • JAZZ PHARMACEUTICALS IRELAND LIMITED [IE]/[IE]
  • JAZZ PHARMACEUTICALS, INC. [US]/[US] (KN)
Inventors
  • HURLEY, Fionn
Agents
  • SCHWARTZMAN, Robert A.
Priority Data
62/539,08831.07.2017US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CARBAMOYL PHENYLALANINOL ANALOGS AND USES THEREOF
(FR) ANALOGUES DE CARBAMOYL PHÉNYLALANINOL ET LEURS UTILISATIONS
Abstract
(EN)
The present invention relates to carbamoyl phenylalaninol analogs and methods of using the same to treat disorders.
(FR)
La présente invention concerne des analogues de carbamoyl-phénylalaninol ainsi que des procédés d’utilisation de ceux-ci pour traiter des troubles.
Also published as
EP2018840981
MXMX/a/2020/001146
Latest bibliographic data on file with the International Bureau