Processing

Please wait...

Settings

Settings

1. WO2018211453 - COMPOSITIONS COMPRISING NAPHTHYRIDINE DERIVATIVES AND ALUMINIUM ADJUVANT FOR USE IN TREATING SOLID TUMORS

Publication Number WO/2018/211453
Publication Date 22.11.2018
International Application No. PCT/IB2018/053481
International Filing Date 17.05.2018
IPC
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
66
Phosphorus compounds
675
having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
19
lyophilised
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45
Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06
Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 31/675 (2006.01)
A61P 35/00 (2006.01)
A61K 39/00 (2006.01)
A61K 9/19 (2006.01)
A61K 45/06 (2006.01)
CPC
A61K 2039/505
A61K 31/675
A61K 33/00
A61K 39/3955
A61K 9/19
A61P 35/00
Applicants
  • NOVARTIS AG [CH/CH]; Lichtstrasse 35 4056 Basel, CH
Inventors
  • COOKE, Michael; US
  • KASIBHATLA, Shailaja; US
  • MILLER, Andrew T.; US
  • WU, Tom Yao-Hsiang; US
Agents
  • NOVARTIS AG; Lichtstrasse 35 4056 Basel, CH
Priority Data
62/508,47419.05.2017US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS COMPRISING NAPHTHYRIDINE DERIVATIVES AND ALUMINIUM ADJUVANT FOR USE IN TREATING SOLID TUMORS
(FR) COMPOSITIONS COMPRENANT DES DÉRIVÉS DE NAPHTYRIDINE ET UN ADJUVANT D'ALUMINIUM DESTINÉES À ÊTRE UTILISÉES DANS LE TRAITEMENT DE TUMEURS SOLIDES
Abstract
(EN)
The invention provided herein includes pharmaceutical compositions comprising a TLR7 agonist having the structure of Formula (A), aluminum-containing particles, and one or more pharmaceutically acceptable excipient. The invention further provides the use of such compositions in the treatment of solid tumors either alone or in combination with one or more additional pharmaceutical compositions.
(FR)
La présente invention concerne des compositions pharmaceutiques comprenant un agoniste de TLR7 ayant la structure de Formule (A), des particules contenant de l'aluminium, et un ou plusieurs excipients pharmaceutiquement acceptables. La présente invention concerne en outre l'utilisation de telles compositions dans le traitement de tumeurs solides soit seules, soit en combinaison avec une ou plusieurs compositions pharmaceutiques supplémentaires.
Also published as
EP2018730857
IL270441
KR1020197037113
RU2019141837
Latest bibliographic data on file with the International Bureau