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1. WO2013173337 - SELF-STABILIZING LINKER CONJUGATES

Publication Number WO/2013/173337
Publication Date 21.11.2013
International Application No. PCT/US2013/040951
International Filing Date 14.05.2013
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
207
Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
02
with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
30
having two double bonds between ring members or between ring members and non-ring members
34
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
36
Oxygen or sulfur atoms
40
2,5-Pyrrolidine-diones
C07D 207/40 (2006.01)
CPC
A61K 47/50
A61K 47/6811
A61K 47/6817
A61K 47/6851
A61K 47/6889
C07K 19/00
Applicants
  • SEATTLE GENETICS, INC. [US/US]; 21823 - 30th Dr. S.E. Bothell, WA 98021, US
Inventors
  • LYON, Robert; US
  • DORONINA, Svetlana; US
  • BOVEE, Timothy; US
Agents
  • KEZER, William, B.; Kilpatrick Townsend & Stockton LLP Eighth Floor Two Embarcadero Center San Francisco, CA 94111, US
Priority Data
13/799,24413.03.2013US
61/647,37315.05.2012US
61/770,98328.02.2013US
61/773,06705.03.2013US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SELF-STABILIZING LINKER CONJUGATES
(FR) CONJUGUÉS DE LIEURS À AUTO-STABILISATION
Abstract
(EN)
The present invention provides Ligand-Drug Conjugates, Drug-Linkers, Linkers, and Ligand-Linker Conjugates comprising a self-stabilizing linker assembly component.
(FR)
La présente invention concerne des conjugués ligand-médicament, des médicament-lieurs, des lieurs, et des conjugués ligand-lieur comprenant un composant ensemble lieur à auto-stabilisation.
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