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1. WO2013018884 - KERATOTIC PLUG REGROWTH INHIBITION AGENT, KERATOTIC PLUG REGROWTH INHIBITION METHOD, AND KERATOTIC PLUG REGROWTH INHIBITION KIT

Publication Number WO/2013/018884
Publication Date 07.02.2013
International Application No. PCT/JP2012/069823
International Filing Date 03.08.2012
IPC
A61K 8/365 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
36Carboxylic acids; Salts or anhydrides thereof
365Hydroxycarboxylic acids; Ketocarboxylic acids
A61K 8/36 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
36Carboxylic acids; Salts or anhydrides thereof
A61K 8/368 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
36Carboxylic acids; Salts or anhydrides thereof
368with carboxyl groups directly bound to carbon atoms of aromatic rings
A61K 8/39 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
39Derivatives containing from 2 to 10 oxyalkylene groups
A61K 8/44 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
40containing nitrogen
44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts, esters or N-acylated derivatives thereof
A61K 8/49 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
49containing heterocyclic compounds
CPC
A61K 8/361
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
36Carboxylic acids; Salts or anhydrides thereof
361Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
A61K 8/365
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
36Carboxylic acids; Salts or anhydrides thereof
365Hydroxycarboxylic acids; Ketocarboxylic acids
A61K 8/416
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
40containing nitrogen
41Amines
416Quaternary ammonium compounds
A61K 8/42
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
40containing nitrogen
42Amides
A61K 8/44
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
40containing nitrogen
44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
A61K 8/463
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
46containing sulfur
463containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
Applicants
  • 株式会社資生堂 SHISEIDO COMPANY, LTD. [JP]/[JP] (AllExceptUS)
  • 麦倉 茂 MUGIKURA, Shigeru [JP]/[JP] (UsOnly)
  • 飯田 年以 IIDA, Toshii [JP]/[JP] (UsOnly)
  • 小野 隆之 ONO, Takayuki [JP]/[JP] (UsOnly)
  • 末継 勝 SUETSUGU, Masaru [JP]/[JP] (UsOnly)
Inventors
  • 麦倉 茂 MUGIKURA, Shigeru
  • 飯田 年以 IIDA, Toshii
  • 小野 隆之 ONO, Takayuki
  • 末継 勝 SUETSUGU, Masaru
Agents
  • 長谷川洋子 HASEGAWA, Yoko
Priority Data
2011-16975003.08.2011JP
2011-16975103.08.2011JP
Publication Language Japanese (ja)
Filing Language Japanese (JA)
Designated States
Title
(EN) KERATOTIC PLUG REGROWTH INHIBITION AGENT, KERATOTIC PLUG REGROWTH INHIBITION METHOD, AND KERATOTIC PLUG REGROWTH INHIBITION KIT
(FR) INHIBITEUR DE LA REFORMATION DE BOUCHONS KÉRATOSIQUES, MÉTHODE D'INHIBITION DE LA REFORMATION DE BOUCHONS KÉRATOSIQUES, ET KIT D'INHIBITION DE LA REFORMATION DE BOUCHONS KÉRATOSIQUES
(JA) 角栓再生抑制剤、角栓再生抑制方法、および角栓再生抑制キット
Abstract
(EN) [Problem] To provide a keratotic plug regrowth inhibition agent, keratotic plug regrowth inhibition method, and keratotic plug regrowth inhibition kit whereby the regrowth of a keratotic plug can be effectively inhibited without causing skin irritation. [Solution] A keratotic plug regrowth inhibition agent, characterized in containing: (a) a specific acid (for example, lactic acid, succinic acid, citric acid, or the like) or a salt thereof; (b) a specific surfactant (for example, fatty acid soap, higher alkyl sulfate ester salt, polyoxyalkylene phytosterol, or the like); and (c) a specific skin irritation mitigation agent (for example, POE/POP dimethyl ether, tranexamic acid, pantothenyl ethyl ether, trimethyl glycine, glycylglycine, or the like). A keratotic plug regrowth inhibition method, in which a skin cleanser including a POE fatty acid ester is applied to the skin and thereafter a keratotic plug regrowth inhibition agent including a specific acid (for example, lactic acid, succinic acid, citric acid, or the like) or a salt thereof is applied to the skin; also, a keratotic plug regrowth inhibition kit comprising the skin cleanser and keratotic plug regrowth inhibition agent.
(FR) La présente invention a trait à un inhibiteur de la reformation de bouchons kératosiques, une méthode d'inhibition de la reformation de bouchons kératosiques, et un kit d'inhibition de la reformation de bouchons kératosiques, grâce auxquels il est possible d'inhiber efficacement la reformation de bouchons kératosiques sans provoquer d'irritation de la peau. L'invention concerne donc un inhibiteur de la reformation de bouchons kératosiques, caractérisé en ce qu'il contient : (a) un acide spécifique (par exemple, l'acide lactique, l'acide succinique, l'acide citrique, ou analogues) ou l'un de ses sels ; (b) un agent tensioactif spécifique (par exemple, un savon d'acide gras, un sel ester sulfate d'alkyle supérieur, un polyoxyalkylène phytostérol, ou analogues) ; et (c) un agent de mitigation de l'irritation de la peau spécifique (par exemple, un éther diméthylique de POE/POP, l'acide tranexamique, un éther de pantothényl-éthyle, la triméthyl-glycine, la glycylglycine, ou analogues). L'invention a également pour objet une méthode d'inhibition de la reformation de bouchons kératosiques, consistant à appliquer sur la peau un nettoyant pour la peau contenant un ester d'acide gras POE et ensuite un inhibiteur de la reformation de bouchons kératosiques contenant un acide spécifique (par exemple, l'acide lactique, l'acide succinique, l'acide citrique, ou analogues) ou l'un de ses sels ; l'invention a également pour objet un kit d'inhibition de la reformation de bouchons kératosiques comprenant le nettoyant pour la peau et l'inhibiteur de la reformation de bouchons kératosiques.
(JA) 課題 肌荒れを起こさずに効果的に角栓の再生を抑制し得る角栓再生抑制剤、角栓再生抑制方法、および角栓再生抑制キットの提供。 解決手段 (a)特定の酸(例えば、乳酸、コハク酸、クエン酸等)あるいはそれらの塩と、(b)特定の界面活性剤(例えば、脂肪酸石鹸、高級アルキル硫酸エステル塩、ポリオキシアルキレンフィトステロール等)と、(c)特定の抗肌荒れ改善剤(例えば、POE・POPジメチルエーテル、トラネキサム酸、パントテニルエチルエーテル、トリメチルグリシン、グリシルグリシン等)を含有することを特徴とする角栓再生抑制剤。 POE脂肪酸エステルを含む皮膚洗浄料を肌へ適用した後に、特定の酸(例えば、乳酸、コハク酸、クエン酸等)あるいはそれらの塩を含む角栓再生抑制剤を皮膚へ適用する角栓再生抑制方法、および前記皮膚洗浄料と角栓再生抑制剤からなる角栓再生抑制キット。
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