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1. JP2022157341 - METHOD FOR MEASURING ANTI-DRUG ANTIBODY

Office
Japan
Application Number 2021061507
Application Date 31.03.2021
Publication Number 2022157341
Publication Date 22.04.2022
Grant Number 7062803
Grant Date 22.04.2022
Publication Kind B1
IPC
C12Q 1/68
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
G01N 33/53
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
CPC
C12Q 1/68
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
G01N 33/53
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
Applicants SEKISUI MEDICAL CO LTD
積水メディカル株式会社
Inventors SEKINO TETSUO
関野 哲男
OMORI AKANE
大森 茜
Agents 特許業務法人 もえぎ特許事務所
Title
(EN) METHOD FOR MEASURING ANTI-DRUG ANTIBODY
(JA) 抗薬物抗体測定方法
Abstract
(EN)

PROBLEM TO BE SOLVED: To provide a simple and inexpensive method for measuring an anti-drug antibody as compared with a conventional method.

SOLUTION: Provided is a double antigen cross-linking immunoassay using the capture nucleic acid and the tracer nucleic acid. By using the capture nucleic acid and the tracer nucleic acid in a double antigen cross-linking immunoassay method, the measurement of an anti-drug antibody can be performed simply and inexpensively. Also, by using the tracer nucleic acid, a highly sensitive detection method using nucleic acid can be employed.

SELECTED DRAWING: Figure 1-4

COPYRIGHT: (C)2023,JPO&INPIT


(JA) 【課題】従来法と比較して、簡便かつ安価な抗薬物抗体の測定法を提供する。
【解決手段】捕獲核酸及びトレーサー核酸を使用する二重抗原架橋イムノアッセイ法を提供する。二重抗原架橋イムノアッセイ法において捕獲核酸及びトレーサー核酸を使用することにより、抗薬物抗体の測定を簡便かつ安価に行うことができる。また、トレーサー核酸を使用することにより、核酸を利用した高感度検出方法を採用することが可能になる。
【選択図】図1-4

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