Processing

Please wait...

Settings

Settings

Goto Application

1. IN202117061581 - PEPTIDES AND METHODS OF USE THEREOF IN TREATING UVEITIS

Office
India
Application Number 202117061581
Application Date 29.12.2021
Publication Number 202117061581
Publication Date 24.06.2022
Publication Kind A
IPC
A61K
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Applicants BIOMARCK PHARMACEUTICALS LTD.
Inventors PARIKH, Indu
BHATIA, Ashish
Priority Data 62/862326 17.06.2019 US
Title
(EN) PEPTIDES AND METHODS OF USE THEREOF IN TREATING UVEITIS
Abstract
(EN) The present disclosure includes methods of treating ocular inflammation or inflammatory ocular conditions, such as uveitis. More specifically the present disclosure relates to inhibiting or reducing the release of inflammatory mediators from inflammatory cells by inhibiting the mechanism associated with the release of inflammatory mediators from granules in inflammatory cells. In this regard, the present disclosure includes an intracellular signaling mechanism that illustrates several novel intracellular targets for pharmacological intervention in disorders involving secretion of inflammatory mediators from vesicles in inflammatory cells. Peptide fragments and variants thereof as disclosed in the present disclosure are useful in such methods.