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1. CO20220003123 - COMPUESTOS FARMACÉUTICOS

Office
Colombia
Application Number 20220003123
Application Date 18.03.2022
Publication Number 20220003123
Publication Date 10.05.2022
Publication Kind A2
IPC
A61P 31/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
C07D 487/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
A61K 31/519
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519ortho- or peri-condensed with heterocyclic rings
A61K 31/5025
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
50Pyridazines; Hydrogenated pyridazines
5025ortho- or peri-condensed with heterocyclic ring systems
Applicants REVIRAL LIMITED
Inventors George Stuart COCKERILL
James GOOD
Craig Alex AVERY
Edward James COCHRANE
Andrew Joseph WARNER
Agents CLAUDIA LUCIA CARO RAMIREZ
Priority Data 1911944.5 20.08.2019 GB
Title
(ES) COMPUESTOS FARMACÉUTICOS
Abstract
(ES) COMPOSICIONES FARMACÉUTICAS Derivados de benzodiacepinas de fórmula (I): en el que: cada uno de R1 y R2 es independientemente H o halo; ya sea (i) T es N, Z es C, y son enlaces, y y están ausentes; o (ii) T es C, Z es N, y son enlaces, y y están ausentes; cada uno de R3 y R4 es independientemente Halo, -OR6, -NR6R7, -COR8, -C(O)OR8, -CON(R8)2 o -R6; R5 es H o halo; cada uno de R6 y R7 es independientemente H o un grupo seleccionado de alquilo C1-C6, cicloalquilo C3-C10, arilo C6-C10, heterociclilo de 4 a 10 miembros y heteroarilo de 4 a 10 miembros, el grupo es sustituido o no sustituido; R8 es H o alquilo C1-C6, cada R8 es el mismo o diferente cuando se presentan dos; n es 0 o 1; y uno de V, W, X y Y es N o CH y los otros tres son CH; y las sales farmacéuticamente aceptables de los mismos son inhibidores de RSV y, por lo tanto, pueden usarse para tratar o prevenir una infección por RSV.
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