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1. WO2018234301 - BACITRACIN AND/OR DAPTOMYCIN COMBINED WITH CANNABIDIOL FOR TREATMENT OF BACTERIAL INFECTIONS

Publication Number WO/2018/234301
Publication Date 27.12.2018
International Application No. PCT/EP2018/066234
International Filing Date 19.06.2018
IPC
A61K 31/352 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 38/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
12Cyclic peptides
A61K 45/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 31/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
CPC
A61K 31/05
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
05Phenols
A61K 31/352
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 38/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
12Cyclic peptides ; , e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 9/0014
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0014Skin, i.e. galenical aspects of topical compositions
A61K 9/0048
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0048Eye, e.g. artificial tears
Applicants
  • SYDDANSK UNIVERSITET [DK]/[DK]
Inventors
  • KLITGAARD, Janne Kudsk,
  • WASSMANN, Claes Søndergaard,
Agents
  • PLOUGMANN VINGTOFT A/S
Priority Data
17176612.419.06.2017EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BACITRACIN AND/OR DAPTOMYCIN COMBINED WITH CANNABIDIOL FOR TREATMENT OF BACTERIAL INFECTIONS
(FR) BACITRACINE ET/OU DAPTOMYCINE COMBINÉE AU CANNABIDIOL POUR LE TRAITEMENT DES INFECTIONS BACTÉRIENNES
Abstract
(EN)
The present invention relates to compositions comprising Cannabidiol (CBD) or pharmaceutically acceptable salts thereof, and bacitracin or pharmaceutically acceptable salts thereof and/or daptomycin or pharmaceutically acceptable salts thereof. The compositions show a synergistic effect in the inhibition of growth of Gram-positive bacteria. Thus, the compositions according to the invention may e.g. find use as medicaments in the treatment of Gram-positive bacterial infections.
(FR)
La présente invention concerne des compositions comprenant du cannabidiol (CBD) ou des sels pharmaceutiquement acceptables de celui-ci, et de la bacitracine ou des sels pharmaceutiquement acceptables de celle-ci et/ou de la daptomycine ou des sels pharmaceutiquement acceptables de celle-ci. Ces compositions ont un effet synergique dans l'inhibition de la croissance des bactéries à Gram positif. Ainsi, les compositions selon l'invention peuvent, p. ex., être utilisées à titre de médicaments dans le traitement des infections par des bactéries à Gram positif.
Also published as
Latest bibliographic data on file with the International Bureau