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1. WO2022126261 - AMERICAN GINSENG ROOT FRACTIONS, PROCESSES OF THEIR PREPARATION AND USES THEREOF

Publication Number WO/2022/126261
Publication Date 23.06.2022
International Application No. PCT/CA2021/051807
International Filing Date 14.12.2021
IPC
A61K 36/258 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
258Panax (ginseng)
A61K 31/715 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
A61P 31/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
A61P 31/14 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
B01D 11/02 2006.1
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
11Solvent extraction
02of solids
C08B 37/00 2006.1
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
BPOLYSACCHARIDES; DERIVATIVES THEREOF
37Preparation of polysaccharides not provided for in groups C08B1/-C08B35/110; Derivatives thereof
Applicants
  • SHAN, Jacqueline J. [CA]/[CA]
Inventors
  • SHAN, Jacqueline J.
Agents
  • BERESKIN & PARR LLP/S.E.N.C.R.L., S.R.L.
Priority Data
63/125,60715.12.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) AMERICAN GINSENG ROOT FRACTIONS, PROCESSES OF THEIR PREPARATION AND USES THEREOF
(FR) FRACTIONS DE RACINE DE GINSENG AMÉRICAIN, LEURS PROCÉDÉS DE PRÉPARATION ET LEURS UTILISATIONS
Abstract
(EN) The present application relates to fractions from a root portion of an American ginseng (Panax quinquefolius) plant, and in particular, an intermediate polysaccharide fraction, a neutral polysaccharide fraction, an acidic polysaccharide rich fraction and an acidic polysaccharide fraction and to processes for their preparation, compositions comprising them, and to their use in therapy. For example, the fractions of the application are useful in the treatment of diseases, disorders or conditions treatable by activating pattern recognition receptors such as Toll-like receptors (TLR) or treatable by activating the innate and adaptive immune response, such as a viral infection.
(FR) La présente demande concerne des fractions d'une partie racinaire d'un plant de ginseng américain (Panax quinquefolius), et en particulier, une fraction de polysaccharide intermédiaire, une fraction de polysaccharide neutre, une fraction riche en polysaccharide acide et une fraction de polysaccharide acide, et des procédés pour leur préparation, des compositions les comprenant, et leur utilisation en thérapie. Par exemple, les fractions de la demande sont utiles dans le traitement de maladies, de troubles ou d'états pouvant être traités par l'activation de récepteurs de reconnaissance de motifs moléculaires, tels que les récepteurs de type Toll (TLR), ou pouvant être traités par l'activation de la réponse immunitaire innée et adaptative, tels qu'une infection virale.
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