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1. WO2022126207 - DRUGS, THERAPEUTIC COMBINATIONS AND METHODS FOR PREVENTING VIRAL AND MICROBIAL INFECTIONS AND THEIR SEQUELAE

Publication Number WO/2022/126207
Publication Date 23.06.2022
International Application No. PCT/AU2021/051526
International Filing Date 20.12.2021
IPC
A61K 31/7048 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7048having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
A61K 31/65 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
65Tetracyclines
A61K 33/30 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33Medicinal preparations containing inorganic active ingredients
24Heavy metals; Compounds thereof
30Zinc; Compounds thereof
A61K 31/216 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
21Esters, e.g. nitroglycerine, selenocyanates
215of carboxylic acids
216of acids having aromatic rings, e.g. benactizyne, clofibrate
A61K 31/59 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
59Compounds containing 9,10-seco-cyclopentahydro- phenanthrene ring systems
A61K 31/403 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403condensed with carbocyclic rings, e.g. carbazole
Applicants
  • TOPELIA AUST LIMITED (ACN 652 771 670) [AU]/[AU]
Inventors
  • BORODY, Thomas Julius
Agents
  • SPRUSON & FERGUSON
Priority Data
63/128,15220.12.2020US
63/178,67123.04.2021US
63/215,04125.06.2021US
63/223,43219.07.2021US
63/241,49807.09.2021US
63/257,19219.10.2021US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) DRUGS, THERAPEUTIC COMBINATIONS AND METHODS FOR PREVENTING VIRAL AND MICROBIAL INFECTIONS AND THEIR SEQUELAE
(FR) MÉDICAMENTS, COMBINAISONS THÉRAPEUTIQUES ET MÉTHODES POUR PRÉVENIR DES INFECTIONS VIRALES ET MICROBIENNES ET LEURS SÉQUELLES
Abstract
(EN) Therapeutic agents, combination therapies, and methods for the treatment of coronavirus infections and associated diseases, particularly COVID-19, are provided. The provided therapeutics include ivermectin (at doses of 0.3 mg/kg or higher), doxycycline, zinc, azithromycin, hydroxychloroquine, fenofibrate, vitamin D, nirmatrelvir, ritonavir, or ribavirin and combinations thereof.
(FR) L'invention concerne des agents thérapeutiques, des polythérapies et des méthodes pour le traitement d'infections à coronavirus et de maladies associées, en particulier la COVID-19. Les agents thérapeutiques fournis comprennent de l'ivermectine (à des doses de 0,3 mg/kg ou plus), de la doxycycline, du zinc, de l'azithromycine, de l'hydroxychloroquine, du fénofibrate, de la vitamine D, du nirmatrelvir, du ritonavir ou de la ribavirine et des combinaisons de ceux-ci.
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