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1. WO2022126179 - OXYTOCIN RECEPTOR MODULATORS

Publication Number WO/2022/126179
Publication Date 23.06.2022
International Application No. PCT/AU2021/051487
International Filing Date 14.12.2021
IPC
C07D 487/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
C07D 487/14 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
12in which the condensed system contains three hetero rings
14Ortho-condensed systems
C07D 491/048 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
491Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/-C07D459/290
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
044with only one oxygen atom as ring hetero atom in the oxygen-containing ring
048the oxygen-containing ring being five-membered
A61P 15/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders; Contraceptives
A61P 15/04 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15Drugs for genital or sexual disorders; Contraceptives
04for inducing labour or abortion; Uterotonics
A61P 19/10 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
08for bone diseases, e.g. rachitism, Paget's disease
10for osteoporosis
Applicants
  • THE UNIVERSITY OF SYDNEY [AU]/[AU]
Inventors
  • KASSIOU, Michael
  • KATTE, Timothy
  • AFZALI, Kiyan
  • REEKIE, Tristan
  • WERRY, Eryn
Agents
  • FPA PATENT ATTORNEYS PTY LTD
Priority Data
202090467714.12.2020AU
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) OXYTOCIN RECEPTOR MODULATORS
(FR) MODULATEURS DU RÉCEPTEUR DE L'OXYTOCINE
Abstract
(EN) This invention relates to compounds of formula (I) and salts, solvates, tautomers, N-oxides, stereoisomers, polymorphs and/or prodrugs thereof. Also disclosed is the use of the compounds of formula (I) to modulate the activity of oxytocin at the oxytocin receptor.
(FR) La présente invention concerne des composés de formule (I) et des sels, des solvates, des tautomères, des N-oxydes, des stéréoisomères, des polymorphes et/ou des promédicaments de ceux-ci. L'invention concerne également l'utilisation des composés de formule (I) pour moduler l'activité de l'oxytocine au niveau du récepteur de l'oxytocine.
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