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1. WO2022013877 - METHOD AND SYSTEM FOR PREPARING A SAMPLE FOR DETECTION OF PROTEINS

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Publication Number WO/2022/013877
Publication Date 20.01.2022
International Application No. PCT/IL2021/050869
International Filing Date 15.07.2021
IPC
A61B 5/08 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
08Measuring devices for evaluating the respiratory organs
G01N 33/497 2006.1
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
483Physical analysis of biological material
497of gaseous biological material, e.g. breath
CPC
A61B 5/082
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
08Detecting, measuring or recording devices for evaluating the respiratory organs
082Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
G01N 1/4022
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1Sampling; Preparing specimens for investigation
28Preparing specimens for investigation ; including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
40Concentrating samples
4022by thermal techniques; Phase changes
G01N 1/44
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1Sampling; Preparing specimens for investigation
28Preparing specimens for investigation ; including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
44Sample treatment involving radiation, e.g. heat
G01N 2001/4033
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1Sampling; Preparing specimens for investigation
28Preparing specimens for investigation ; including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
40Concentrating samples
4022by thermal techniques; Phase changes
4033sample concentrated on a cold spot, e.g. condensation or distillation
G01N 2333/165
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2333Assays involving biological materials from specific organisms or of a specific nature
005from viruses
08RNA viruses
165Coronaviridae, e.g. avian infectious bronchitis virus
G01N 33/497
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
483Physical analysis of biological material
497of gaseous biological material, e.g. breath
Applicants
  • BREATH OF HEALTH LTD. [IL]/[IL]
Inventors
  • LAOR, Marsel Arie Laor
Agents
  • GEYRA, Assaf
  • KESTEN, Dov
  • FRYDMAN, Idan
Priority Data
63/052,96517.07.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHOD AND SYSTEM FOR PREPARING A SAMPLE FOR DETECTION OF PROTEINS
(FR) PROCÉDÉ ET SYSTÈME DE PRÉPARATION D’UN ÉCHANTILLON POUR LA DÉTECTION DE PROTÉINES
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Abstract
(EN) The present invention provides a system including a pump configured to pump an air sample, from a container to a cooling chamber, at a capacity of at least 0.5 liter/sec, the cooling chamber is configured to cool the exhaled air sample to a sub-zero temperature, and is in fluid connection to a spectrometer test chamber; an inert gas source, configured to supply an inert gas to the test chamber at a pressure higher than the atmospheric pressure; and a heating unit for heating said air sample. Further provided is a method for preparing an air sample for detection of a mixture of proteins.
(FR) La présente invention concerne un système comprenant une pompe configurée pour pomper un échantillon d’air, depuis un récipient vers une chambre de refroidissement, à une capacité d’au moins 0,5 litre/s, la chambre de refroidissement étant configurée pour refroidir l’échantillon d’air expiré à une température au-dessous de zéro, et est en raccordement fluidique avec une chambre d’essai de spectromètre ; une source de gaz inerte, configurée pour distribuer un gaz inerte dans la chambre d’essai à une pression supérieure à la pression atmosphérique ; et une unité de chauffage pour chauffer ledit échantillon d’air. L’invention concerne en outre un procédé de préparation d’un échantillon d’air pour la détection d’un mélange de protéines.
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