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1. WO2022125482 - ANTIBODIES TO GALECTIN-3 AND METHODS OF USE THEREOF

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Publication Number WO/2022/125482
Publication Date 16.06.2022
International Application No. PCT/US2021/062099
International Filing Date 07.12.2021
IPC
A61K 39/395 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61K 39/44 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
44Antibodies bound to carriers
A61K 49/16 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
06Nuclear magnetic resonance (NMR) contrast preparations; Magnetic resonance imaging (MRI) contrast preparations
08characterised by the carrier
10Organic compounds
14Peptides, e.g. proteins
16Antibodies; Immunoglobulins; Fragments thereof
Applicants
  • MEMORIAL SLOAN KETTERING CANCER CENTER [US]/[US]
  • TRI-INSTITUTIONAL THERAPEUTICS DISCOVERY INSTITUTE, INC. [US]/[US]
Inventors
  • SPRIGGS, David
  • THAPI, Dharmarao
  • LORENZ, Ivo C.
  • WHITE, Thomas E.
Agents
  • EWING, James F.
  • FERNANDES, Jolene S.
Priority Data
63/122,71408.12.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) ANTIBODIES TO GALECTIN-3 AND METHODS OF USE THEREOF
(FR) ANTICORPS DIRIGÉS CONTRE LA GALECTINE-3 ET LEURS MÉTHODES D'UTILISATION
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Abstract
(EN) Provided herein are compositions, methods, and uses involving antibodies that specifically bind the Galectin-3 (LGALS3) carbohydrate binding domain (CBD). Also provided herein are uses and methods for managing, treating, or preventing disorders, such as cancer.
(FR) L'invention concerne des compositions, des méthodes et des utilisations impliquant des anticorps qui se lient spécifiquement au domaine de liaison des glucides (CDB) de la galectine-3 (LGALS3). L'invention concerne également des utilisations et des méthodes de gestion, de traitement ou de prévention de troubles, tels que le cancer.
Latest bibliographic data on file with the International Bureau
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