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1. WO2022139341 - PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OBSESSIVE-COMPULSIVE DISORDER, TIC DISORDER, OR TOURETTE SYNDROME COMPRISING CLEMASTINE

Publication Number WO/2022/139341
Publication Date 30.06.2022
International Application No. PCT/KR2021/019253
International Filing Date 17.12.2021
IPC
A61K 31/40 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A61K 45/06 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 25/18 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
A61P 25/14 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
14for treating abnormal movements, e.g. chorea, dyskinesia
CPC
A61K 31/40
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 25/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
14for treating abnormal movements, e.g. chorea, dyskinesia
A61P 25/18
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
Applicants
  • 주식회사 스탠다임 STANDIGM INC. [KR]/[KR]
  • 한국과학기술연구원 KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY [KR]/[KR]
Inventors
  • 추현아 CHOO, Hyunah
  • 김정진 KIM, Jeongjin
  • 강택 KANG, Taek
  • 우지완 WOO, Ji Wan
  • 곽리나 KWAG, Rina
  • 이보라 LEE, Bora
  • 장성홍 JANG, Seong Hong
  • 조약돌 CHO, Yakdol
  • 한대희 HAN, Daehee
  • 구희정 KOO, Hee Jung
Agents
  • 류종우 RYU, Jong Woo
  • 이내영 LEE, Rae Young
  • 한윤호 HAN, Yun Ho
Priority Data
10-2020-017943821.12.2020KR
Publication Language Korean (ko)
Filing Language Korean (KO)
Designated States
Title
(EN) PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING OBSESSIVE-COMPULSIVE DISORDER, TIC DISORDER, OR TOURETTE SYNDROME COMPRISING CLEMASTINE
(FR) COMPOSITION PHARMACEUTIQUE POUR LA PRÉVENTION OU LE TRAITEMENT D'UN TROUBLE OBSESSIONNEL COMPULSIF, D'UN TROUBLE DE TIC OU D'UN SYNDROME DE LA TOURETTE COMPRENANT DE LA CLÉMASTINE
(KO) 클레마스틴을 포함하는 강박장애, 틱 장애 또는 뚜렛 증후군 예방 또는 치료용 약학 조성물
Abstract
(EN) The present invention relates to: a pharmaceutical composition for the prevention or treatment of obsessive-compulsive disorder, tic disorder, or tourette syndrome, the pharmaceutical composition comprising clemastine or a pharmaceutically acceptable salt thereof as an active ingredient; a food composition; a method for preventing or treating obsessive-compulsive disorder, tic disorder, or tourette syndrome by using same; and use thereof. The pharmaceutical composition according to the present invention has an excellent effect of reducing repetitive behavior patterns, and thus is useful for the prevention or treatment of repetitive behavior disorder such as obsessive-compulsive disorder, tic disorder, or tourette syndrome.
(FR) La présente invention concerne une composition pharmaceutique pour la prévention ou le traitement d'un trouble obsessionnel compulsif, d'un trouble de tic ou d'un syndrome de la Tourette, la composition pharmaceutique comprenant de la clémastine ou un sel pharmaceutiquement acceptable de celle-ci en tant que principe actif ; une composition alimentaire ; un procédé pour la prévention ou le traitement d'un trouble obsessionnel compulsif, d'un trouble de tic ou d'un syndrome de la Tourette en utilisant celui-ci ; et son utilisation. La composition pharmaceutique selon la présente invention a un excellent effet de réduction de motifs de comportement répétitifs, et est par conséquent utile pour la prévention ou le traitement d'un trouble du comportement répétitif tel que le trouble obsessionnel compulsif, le trouble de tic ou le syndrome de la Tourette.
(KO) 본 발명은 클레마스틴 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 강박장애, 틱 장애 또는 뚜렛 증후군의 예방 또는 치료용 약학 조성물, 식품 조성물, 이를 이용한 강박장애, 틱 장애 또는 뚜렛 증후군의 예방 또는 치료 방법, 및 이의 용도에 관한 것으로, 본 발명에 따른 약학 조성물은 반복행동 패턴을 개선하는 효과가 탁월하여, 강박장애, 틱 장애 또는 뚜렛 증후군과 같은 반복행동 장애의 예방 또는 치료에 유용하다.
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