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1. WO2021204814 - NACHR, SUCH AS NICOTINE, FOR USE IN THE PREVENTION AND THE TREATMENT OF COVID-19 DISEASE

Publication Number WO/2021/204814
Publication Date 14.10.2021
International Application No. PCT/EP2021/058960
International Filing Date 06.04.2021
IPC
A61K 31/465 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
465Nicotine; Derivatives thereof
A61P 31/14 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
A61K 9/70 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases
CPC
A61K 31/465
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
465Nicotine; Derivatives thereof
A61K 9/7038
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases ; ; Films; Fibres of the matrix type containing drug;
7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
703characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
A61P 31/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
Applicants
  • ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS [FR]/[FR]
  • INSTITUT PASTEUR [FR]/[FR]
  • SORBONNE UNIVERSITE [FR]/[FR]
  • CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) [FR]/[FR]
Inventors
  • MIYARA, Makoto
  • AMOURA, Zahir
  • TUBACH, Florence
  • REY, Felix Augusto
  • CHANGEUX, Jean-Pierre
Agents
  • REGIMBEAU
Priority Data
20315125.306.04.2020EP
20315196.420.04.2020EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) NACHR, SUCH AS NICOTINE, FOR USE IN THE PREVENTION AND THE TREATMENT OF COVID-19 DISEASE
(FR) NACHR, TEL QUE DE LA NICOTINE, DESTINÉ À ÊTRE UTILISÉ DANS LA PRÉVENTION ET LE TRAITEMENT DE LA COVID-19
Abstract
(EN) The invention relates to a ligand having a modulatory effect on neuronal nicotinic acetylcholine receptor (nAChR) or a pharmaceutical salt thereof for use for preventing and/or treating viral infections due to at least one betacoronavirus, preferably a Severe Acute Respiratory Syndrome-related coronavirus.
(FR) L'invention concerne un ligand ayant un effet modulateur sur le récepteur nicotinique neuronal de l'acétylcholine (nAChR) ou un sel pharmaceutique de celui-ci destiné à être utilisé pour prévenir et/ou traiter des infections virales dues à au moins un bêtacoronavirus, de préférence un coronavirus associé au syndrome respiratoire aigu sévère.
Related patent documents
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