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1. WO2021226602 - PLACENTA-DERIVED ADHERENT (PDA) STEM CELL FOR THE TREATMENT OF ADULTS WITH SARS-COV-2 RELATED ACUTE RESPIRATORY FAILURE AND ARDS (COVID-19)

Publication Number WO/2021/226602
Publication Date 11.11.2021
International Application No. PCT/US2021/031649
International Filing Date 10.05.2021
IPC
A61K 35/50 2015.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
48Reproductive organs
50Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
A61P 11/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
CPC
A61K 35/50
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
48Reproductive organs
50Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
Applicants
  • CELULARITY INC. [US]/[US]
Inventors
  • HARIRI, Robert J.
  • ZHANG, Xiaokui
  • HE, Shuyang
  • KARASIEWICZ-MENDEZ, Kathy
  • YE, Qian
  • MAHLAKÕIV, Tanel
  • HERB, Stacy
  • CASPER, Corey
Agents
  • KNUDSEN, Geoffry T.
Priority Data
63/022,38008.05.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) PLACENTA-DERIVED ADHERENT (PDA) STEM CELL FOR THE TREATMENT OF ADULTS WITH SARS-COV-2 RELATED ACUTE RESPIRATORY FAILURE AND ARDS (COVID-19)
(FR) CELLULE SOUCHE ADHÉRENTE DÉRIVÉE DU PLACENTA (PDA) POUR LE TRAITEMENT D'ADULTES ATTEINTS D'UNE INSUFFISANCE RESPIRATOIRE AIGUË ASSOCIÉE AU SRAS-COV-2 ET DU SDRA (COVID-19)
Abstract
(EN) Provided herein are methods of using CD10+, CD34-, CD105+, CD200+ tissue culture plastic-adherent placental cells, e.g. placental stem cells, in the treatment of SARS-CoV-2 related acute respiratory failure and ARDS (COVID-19).
(FR) L'invention concerne des procédés d'utilisation de cellules placentaires adhérentes à du plastique de culture de tissu CD10+, CD34-, CD105+, CD200+, par exemple des cellules souches placentaires, dans le traitement d'une insuffisance respiratoire aiguë associée au SARS-CoV-2 et du SDRA (COVID-19)
Latest bibliographic data on file with the International Bureau