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1. WO2021112795 - ORAL DOSAGE FORMS CONTAINING INDOMETHACIN

Publication Number WO/2021/112795
Publication Date 10.06.2021
International Application No. PCT/TR2020/051157
International Filing Date 24.11.2020
IPC
A61K 31/405 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403condensed with carbocyclic rings, e.g. carbazole
404Indoles, e.g. pindolol
405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
A61K 9/51 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
50Microcapsules
51Nanocapsules
A61K 47/32 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
CPC
A61K 31/405
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403condensed with carbocyclic rings, e.g. carbazole
404Indoles, e.g. pindolol
405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
A61K 9/5138
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
50Microcapsules ; having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
51Nanocapsules; Nanoparticles;
5107Excipients; Inactive ingredients
513Organic macromolecular compounds; Dendrimers
5138obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Applicants
  • ATATÜRK ÜNİVERSİTESİ BİLİMSEL ARAŞTIRMA PROJELERİ BİRİMİ [TR]/[TR]
Inventors
  • ÖZAKAR, Emrah
  • BERGİŞADİ, Nazan
  • HALLI, Bekir Ufuk
Agents
  • DESTEK PATENT INC.
Priority Data
2019/1932105.12.2019TR
Publication Language English (EN)
Filing Language Turkish (TR)
Designated States
Title
(EN) ORAL DOSAGE FORMS CONTAINING INDOMETHACIN
(FR) FORMES POSOLOGIQUES ORALES CONTENANT DE L'INDOMÉTACINE
Abstract
(EN)
The invention relates to an oral dosage form containing Indomethacin which also provides effective treatment of pain, fever or inflammation while minimizing gastrointestinal system side effects. The invention relates in particular to an oral dosage form containing Indomethacin, polyvinyl alcohol and enteric coating; and an oral dosage form containing Indomethacin, a carrier copolymer, polyvinyl alcohol and enteric coating and manufacturing methods thereof.
(FR)
L'invention concerne une forme posologique orale contenant de l'indométacine qui permet également un traitement efficace de la douleur, de la fièvre ou de l'inflammation tout en réduisant au minimum les effets secondaires du système gastro-intestinal. L'invention concerne en particulier une forme posologique orale contenant de l'indométacine, de l'alcool polyvinylique et un enrobage entérique ; et une forme posologique orale contenant de l'indométacine, un copolymère porteur, un alcool polyvinylique et un revêtement entérique et des procédés de fabrication associés.
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