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1. WO2021110064 - NEW MULTI-FUNCTIONAL OLIGOPEPTIDES

Publication Number WO/2021/110064
Publication Date 10.06.2021
International Application No. PCT/CN2020/133439
International Filing Date 02.12.2020
IPC
A61K 38/17 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
A61P 17/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
C07D 215/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
215Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
Applicants
  • JIANGYIN USUN BIOCHEMICAL TECHNOLOGY CO., LTD. [CN]/[CN]
Inventors
  • JANSON, Jan-Christer
  • GU, Ming
  • SONG, Maoqian
  • SAMUELSSON, Bengt Ingemar
Agents
  • WU, FENG & ZHANG
Priority Data
PCT/CN2019/12239102.12.2019CN
PCT/CN2020/12717606.11.2020CN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NEW MULTI-FUNCTIONAL OLIGOPEPTIDES
(FR) NOUVEAUX OLIGOPEPTIDES MULTIFONCTIONNELS
Abstract
(EN)
There is provided a compound of formula (I), A-Q-B I wherein Q represents a structural fragment of formula (II), wherein: the squiggly lines and m have meanings given in the description, and wherein A and B have meanings given in the description, but may represent a peptide component of the amino acid sequence: [W-Lys-X1-Ser-U-X2-Y]n-W-Lys-X1-Ser-U-X2-Y--- (SEQ ID No: 3) wherein the dashed line, n, W, X1, U, X2 and Y have meanings given in the description, which compounds are useful in medicine, including as pharmaceutical excipients, adhesives and film-forming materials and/or are useful in the treatment of conditions characterised by inflammation, including wounds, burns, and disorders of the mucosa, such as anorectal diseases, inflammatory bowel diseases, gynaecological diseases and dental diseases.
(FR)
L'invention concerne un composé de formule I, A-Q-B I Q représentant un fragment structural de formule II : les lignes ondulées et m ayant les significations données dans la description, et A et B ayant les significations données dans la description, mais peuvent représenter un composant peptidique de la séquence d'acides aminés : [W-Lys-X1-Ser-U-X2-Y]n-W-Lys-X1-Ser-U-X2-Y--- (SEQ ID No : 3), la ligne en pointillé, n, W, X1, U, X2 et Y ayant les significations données dans la description, lesdits composés étant utiles en médecine, y compris en tant qu'excipients pharmaceutiques, adhésifs et matériaux filmogènes et/ou étant utiles dans le traitement d'états caractérisés par une inflammation, y compris des plaies, des brûlures et des troubles de la muqueuse, tels que des maladies anorectales, des maladies intestinales inflammatoires, des maladies gynécologiques et des maladies dentaires.
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