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1. WO2021109713 - USE AND PHARMACEUTICAL COMPOSITION OF PHENYLISOXAZOLYL METHYLENE-NAPHTHALENE-ETHER DERIVATIVES

Publication Number WO/2021/109713
Publication Date 10.06.2021
International Application No. PCT/CN2020/120370
International Filing Date 12.10.2020
IPC
C07D 417/12 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
417Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/196
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
A61K 31/42 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
42Oxazoles
A61P 31/20 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
20for DNA viruses
Applicants
  • GANNEX PHARMA CO., LTD. [CN]/[CN]
Inventors
  • YANG, Bailing
  • KRISTJAN, Gudmundsson
  • DONG, Liuyu
  • CHEN, James
Agents
  • PANAWELL & PARTNERS, LLC
Priority Data
PCT/CN2019/12259503.12.2019CN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) USE AND PHARMACEUTICAL COMPOSITION OF PHENYLISOXAZOLYL METHYLENE-NAPHTHALENE-ETHER DERIVATIVES
(FR) UTILISATION ET COMPOSITION PHARMACEUTIQUE DE DÉRIVÉS DE PHÉNYLISOXAZOLYL MÉTHYLÈNE-NAPHTALÈNE-ÉTHER
Abstract
(EN)
Provided are a method of treating or preventing infection with hepatitis B virus in a human or animal, comprising administering to the human or animal in need thereof a therapeutically effective amount of a phenylisoxazolyl methylene-naphthalene-ether derivative having a structure of formula(I); use of a phenylisoxazolyl methylene-naphthalene-ether derivative having a structure of formula(I) in the preparation of a pharmaceutical composition for anti-hepatitis B virus and a pharmaceutical composition for anti-hepatitis B virus.
(FR)
L'invention concerne une méthode de traitement ou de prévention d'une infection par le virus de l'hépatite B chez un être humain ou un animal, comprenant l'administration à l'être humain ou à l'animal qui le nécessite d'une quantité thérapeutiquement efficace d'un dérivé de phénylisoxazolyl méthylène-naphtalène-éther ayant une structure de formule (I) ; l'utilisation d'un dérivé de phénylisoxazolyl méthylène-naphtalène-éther ayant une structure de formule (I) dans la préparation d'une composition pharmaceutique de lutte contre le virus de hépatite B et une composition pharmaceutique pour la lutte contre le virus de l'hépatite B.
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