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1. WO2021109704 - CHRONIC WOUND HEALING COMPOSITION AND APPLICATION THEREOF

Publication Number WO/2021/109704
Publication Date 10.06.2021
International Application No. PCT/CN2020/118933
International Filing Date 29.09.2020
IPC
A61K 31/7032 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
7032attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyl-diacylglycerides, lactobionic acid, gangliosides
A61K 31/045 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
A61K 31/555 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
555containing heavy metals, e.g. hemin, hematin, melarsoprol
A61P 17/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
02for treating wounds, ulcers, burns, scars, keloids, or the like
A61P 3/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
Applicants
  • 罗胥恩 LO, Hsu En [CN]/[CN]
Inventors
  • 罗胥恩 LO, Hsu En
Agents
  • 北京戈程知识产权代理有限公司 GE CHENG & CO., LTD
Priority Data
201911241631.106.12.2019CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) CHRONIC WOUND HEALING COMPOSITION AND APPLICATION THEREOF
(FR) COMPOSITION DE CICATRISATION DE PLAIES CHRONIQUES ET SON APPLICATION
(ZH) 慢性伤口愈合组合物及其应用
Abstract
(EN)
A composition having a chronic wound healing effect, particularly diabetic wound healing; the composition is mainly composed of the following three components: (1) an anti-inflammatory agent, selected from a group consisting of acteoside, isoacteoside, and a combination thereof, (2) an astringent, selected from a group consisting of gallic acid, hypogallic acid, a salt thereof, and a combination thereof, and (3) a cooling agent, selected from a group consisting of borneol, menthol, and a combination thereof, the foregoing may be combined with one or more pharmaceutically acceptable carriers as needed. A use of the described composition in preparing a medicament for treating chronic wounds, particularly diabetic wounds.
(FR)
L'invention concerne une composition ayant un effet de cicatrisation de plaie chronique, en particulier une cicatrisation de plaie diabétique ; la composition est principalement composée des trois composants suivants : (1) un agent anti-inflammatoire, choisi dans un groupe constitué par l'actéoside, l'isoactéoside et une combinaison de ceux-ci, (2) un astringent, choisi dans un groupe constitué par l'acide gallique, l'acide hypogallique, un sel de ceux-ci, et une combinaison de ceux-ci, et (3) un agent rafraîchissant, choisi dans un groupe constitué par le bornéol, le menthol, et une combinaison de ceux-ci, ce qui précède peut être combiné à un ou plusieurs excipients pharmaceutiquement acceptables selon les besoins. L'invention concerne également une utilisation de la composition décrite dans la préparation d'un médicament pour le traitement de plaies chroniques, en particulier de plaies diabétiques.
(ZH)
一种具有慢性伤口愈合功效的组合物,尤指糖尿病伤口愈合,其主要由下列三组分组成:(1)一种抗发炎剂,选自类叶升麻苷、异类叶升麻苷及其组合组成的群,(2)一种收敛剂,选自没食子酸、次没食子酸、其盐类及其组合组成的群,以及(3)一种清凉剂,选自龙脑、薄荷脑及其组合组成的群,并视需要与一种或以上医药上可接受的载剂组合。该组合物用于制备治疗慢性伤口药剂的用途,尤指糖尿病伤口。
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