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1. WO2021081357 - TREATMENT OF EPILEPTIC CONDITIONS WITH GABAA RECEPTOR MODULATORS

Publication Number WO/2021/081357
Publication Date 29.04.2021
International Application No. PCT/US2020/057104
International Filing Date 23.10.2020
IPC
A61K 31/4196 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
41961,2,4-Triazoles
C07D 249/08 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
249Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
02not condensed with other rings
081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
C07D 249/16 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
249Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
16condensed with carbocyclic rings or ring systems
A61P 25/08 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
08Antiepileptics; Anticonvulsants
Applicants
  • NEUROCYCLE THERAPEUTICS, INC. [US]/[US]
Inventors
  • HUBBS, Jed
  • TOCZKO, Matthew
Agents
  • CHEN, Ying
Priority Data
62/925,08123.10.2019US
62/950,67419.12.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) TREATMENT OF EPILEPTIC CONDITIONS WITH GABAA RECEPTOR MODULATORS
(FR) TRAITEMENT D'AFFECTIONS ÉPILEPTIQUES AVEC DES MODULATEURS DU RÉCEPTEUR GABAA
Abstract
(EN)
Disclosed herein are GABAA receptor modulators and compositions comprising GABAA receptor modulators for treatment of epileptic conditions. Also disclosed herein are methods of treating epileptic conditions in a subject by administering a GABAA receptor modulators or composition as described herein.
(FR)
Des modulateurs du récepteur GABAA et des compositions comprenant des modulateurs du récepteur GABAA pour le traitement d'affections épileptiques, sont divulgués. Sont également divulguées des méthodes de traitement d'affections épileptiques chez un sujet, par l'administration de modulateurs du récepteur GABAA ou d'une composition selon l'invention.
Latest bibliographic data on file with the International Bureau