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1. WO2022160156 - LIGASE FUSION PROTEINS AND APPLICATIONS THEREOF

Publication Number WO/2022/160156
Publication Date 04.08.2022
International Application No. PCT/CN2021/074082
International Filing Date 28.01.2021
IPC
C12N 15/62 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
62DNA sequences coding for fusion proteins
A61K 31/537 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
535having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
537spiro-condensed or forming part of bridged ring systems
C07K 4/00 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
4Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
Applicants
  • GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. [CN]/[CN]
Inventors
  • QIN, Gang
  • LV, Cao
  • WALTER, Joachim
  • WERNER, Rolf
  • ZHONG, Yunpeng
Agents
  • NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD.
Priority Data
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) LIGASE FUSION PROTEINS AND APPLICATIONS THEREOF
(FR) PROTÉINES DE FUSION DE LIGASE ET APPLICATIONS ASSOCIÉES
Abstract
(EN) The present disclosure relates to the field of biotechnology. In particular, provided are a ligase fusion protein and an immobilized ligase comprising the same. Also provided is use of the ligase fusion protein or the immobilized ligase in the preparation of conjugates. Further provided is a process for the preparation of conjugates using a ligase or a ligase unit.
(FR) La présente divulgation concerne le domaine de la biotechnologie. En particulier, la divulgation concerne une protéine de fusion de ligase et une ligase immobilisée comprenant celle-ci. La divulgation concerne également l'utilisation de la protéine de fusion de ligase ou de la ligase immobilisée dans la préparation de conjugués. L'invention concerne en outre un procédé de préparation de conjugués à l'aide d'une ligase ou d'une unité de ligase.
Latest bibliographic data on file with the International Bureau