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1. WO2022160138 - BENZOXAZINE-4-ONE COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF

Publication Number WO/2022/160138
Publication Date 04.08.2022
International Application No. PCT/CN2021/074002
International Filing Date 27.01.2021
IPC
C07D 413/12 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
413Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
C07D 471/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
A61K 31/536 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
535having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
536ortho- or peri-condensed with carbocyclic ring systems
A61K 31/537 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
535having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
537spiro-condensed or forming part of bridged ring systems
A61P 3/10 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
08for glucose homeostasis
10for hyperglycaemia, e.g. antidiabetics
A61P 13/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
12of the kidneys
Applicants
  • 承德医学院 CHENGDE MEDICAL UNIVERSITY [CN]/[CN]
Inventors
  • 张丽颖 ZHANG, Liying
Agents
  • 北京知元同创知识产权代理事务所(普通合伙) BEIJING ORIGINTELLIGENCE IP LAW FIRM
Priority Data
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) BENZOXAZINE-4-ONE COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF
(FR) COMPOSÉ DE BENZOXAZINE-4-ONE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION MÉDICALE
(ZH) 苯并嗪-4-酮类化合物、其制备方法及医药用途
Abstract
(EN) The present invention relates to a benzoxazine-4-one compound represented by formula (I) that acts as a glycogen phosphorylase inhibitor, a preparation method therefor, and a use thereof in a drug for the treatment and/or prevention of diseases associated with glycogen metabolism abnormalities.
(FR) La présente invention concerne un composé de benzoxazine-4-one représenté par la formule (I) qui agit en tant qu'inhibiteur de la glycogène phosphorylase, son procédé de préparation et son utilisation dans un médicament pour le traitement et/ou la prévention de maladies associées à des anomalies du métabolisme du glycogène.
(ZH) 涉及作为糖原磷酸化酶抑制剂的式(I)苯并嗪-4-酮化合物、其制备方法及其用于治疗和/或预防与糖原代谢异常相关的疾病的药物中的用途。
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