Processing

Please wait...

Settings

Settings

Goto Application

1. WO2021209009 - METHODS AND COMPOSITIONS FOR HIGH-THROUGHPUT TARGET SEQUENCING IN SINGLE CELLS

Publication Number WO/2021/209009
Publication Date 21.10.2021
International Application No. PCT/CN2021/087517
International Filing Date 15.04.2021
IPC
C12Q 1/68 2018.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
C12M 1/00 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
CPC
C12Q 1/6806
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
Applicants
  • SINGLERON (NANJING) BIOTECHNOLOGIES, LTD. [CN]/[CN]
Inventors
  • FANG, Nan
  • ZHU, Wenqi
  • DING, Xiuheng
Agents
  • BEYOND ATTORNEYS AT LAW
Priority Data
PCT/CN2020/08518516.04.2020CN
PCT/CN2020/08752528.04.2020CN
PCT/CN2021/08561006.04.2021CN
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND COMPOSITIONS FOR HIGH-THROUGHPUT TARGET SEQUENCING IN SINGLE CELLS
(FR) PROCÉDÉS ET COMPOSITIONS POUR LE SÉQUENÇAGE DE CIBLE À HAUT DÉBIT DANS DES CELLULES UNIQUES
Abstract
(EN) Provided include methods, compositions and kits for single cell target sequencing, including but not limited to, high-throughput detection of nucleic acid sequences of single cell T cell receptor, high-throughput detection of expressed viral sequences in host cells, detection of cancer druggable mutations (e.g., lung cancer druggable mutations) in single cells, and simultaneous detection of targeted regions and whole transcriptome in single cells.
(FR) L'invention concerne des procédés, des compositions et des kits pour le séquençage de cible à cellule unique, comprenant, mais sans y être limitées, la détection à haut débit de séquences d'acide nucléique d'un récepteur de lymphocytes T à cellule unique, la détection à haut débit de séquences virales exprimées dans des cellules hôtes, la détection de mutations cancéreuses pouvant être modifiées par l'administration d'un médicament (par exemple, des mutations du cancer du poumon pouvant être modifiées par administration d'un médicament) dans des cellules uniques, ainsi que la détection simultanée de régions ciblées et du transcriptome entier dans des cellules individuelles.
Latest bibliographic data on file with the International Bureau