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1. WO2022094711 - PROCESS FOR PREPARATION OF ADVANCED INTERMEDIATE FOR ERIBULIN SYNTHESYS

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Publication Number WO/2022/094711
Publication Date 12.05.2022
International Application No. PCT/CA2021/051567
International Filing Date 04.11.2021
IPC
C07D 493/14 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
493Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
12in which the condensed system contains three hetero rings
14Ortho-condensed systems
C07D 317/72 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
317Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
08having the hetero atoms in positions 1 and 3
72spiro-condensed with carbocyclic rings
C07D 493/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
493Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
C07H 15/207 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
15Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
20Carbocyclic rings
207Cyclohexane rings not substituted by nitrogen atoms, e.g. kasugamycins
C07H 9/02 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
9Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
02the hetero ring containing only oxygen as ring hetero atoms
Applicants
  • EUROFINS CDMO ALPHORA INC. [CA]/[CA]
Inventors
  • BEXRUD, Jason
  • RUDOLPH, Alena
  • GORIN, Boris
  • ZHAI, Huimin
  • NGUYEN, Kiem
  • LUONG, Anne
  • ALBERICO, Dino
Agents
  • RIDOUT & MAYBEE LLP
  • AGHA, Kazim
Priority Data
3,098,16405.11.2020CA
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) PROCESS FOR PREPARATION OF ADVANCED INTERMEDIATE FOR ERIBULIN SYNTHESYS
(FR) PROCÉDÉ DE PRÉPARATION D'INTERMÉDIAIRE AVANCÉ POUR LA SYNTHÈSE D'ÉRIBULINE
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Abstract
(EN) Disclosed is a process of preparation of a compound of formula 13, and intermediates prepared and used in the preparation of the compound of formula 13.
(FR) L'invention concerne un procédé de préparation d'un composé de formule 13, et des intermédiaires préparés et utilisés dans la préparation du composé de formule 13.
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