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1. WO2022166283 - CARBOHYDRATE COMPOSITION AS PHARMACEUTICAL COMPOSITION, AND USE THEREOF

Publication Number WO/2022/166283
Publication Date 11.08.2022
International Application No. PCT/CN2021/128375
International Filing Date 03.11.2021
IPC
A61K 31/715 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
A61K 8/73 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
72containing organic macromolecular compounds
73Polysaccharides
A61P 37/08 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
37Drugs for immunological or allergic disorders
08Antiallergic agents
A61P 29/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
A61Q 19/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
CPC
A23L 33/00
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
A61K 31/573
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
57substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
573substituted in position 21, e.g. cortisone, dexamethasone, prednisone ; or aldosterone
A61K 47/26
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
A61K 8/365
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
36Carboxylic acids; Salts or anhydrides thereof
365Hydroxycarboxylic acids; Ketocarboxylic acids
A61K 8/60
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
60Sugars; Derivatives thereof
A61K 9/0014
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0014Skin, i.e. galenical aspects of topical compositions
Applicants
  • 株式会社麦德凯日本 MEDGAEA JAPAN CO., LTD. [JP]/[JP]
  • 麦德凯生科股份有限公司 MEDGAEA LIFE SCIENCES LTD. [CN]/[CN]
Inventors
  • 吴彰哲 WU, Chang-Jer
  • 陈伯瑞 CHEN, Bo-Rui
  • 洪志骏 HONG, Chih-Chun
  • 黄郁婷 HUANG, Yuh-Ting
  • 伊波匡彦 IHA, Masahiko
  • 友利诚 TOMORI, Makoto
Agents
  • 北京同立钧成知识产权代理有限公司 LEADER PATENT & TRADEMARK FIRM
Priority Data
63/147,20508.02.2021US
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) CARBOHYDRATE COMPOSITION AS PHARMACEUTICAL COMPOSITION, AND USE THEREOF
(FR) COMPOSITION DE GLUCIDE EN TANT QUE COMPOSITION PHARMACEUTIQUE, ET SON UTILISATION
(ZH) 醣类组合物作为医药组成物及其用途
Abstract
(EN) The present invention provides a carbohydrate composition as a pharmaceutical composition, and use thereof. The carbohydrate composition comprises fucose, glucuronic acid, galactose, and arabinose. Based on the total weight of the carbohydrate composition, the content of the fucose is 45.5 wt% to 76 wt%, the content of the glucuronic acid is 11 wt% to 19 wt%, the content of the galactose is 4.5 wt% to 14.5 wt%, and the content of the arabinose is 5.5 wt% to 18 wt%. A pharmaceutical composition comprising the carbohydrate composition is provided. The carbohydrate composition and the pharmaceutical composition provided by the present invention can achieve the effects of taking care of the skin, inhibiting skin allergy, inhibiting skin inflammation, or alleviating atopic dermatitis.
(FR) La présente invention concerne une composition de glucide en tant que composition pharmaceutique, et son utilisation. La composition de glucide comprend du fucose, de l'acide glucuronique, du galactose et de l'arabinose. Sur la base du poids total de la composition de glucide, la teneur en fucose est de 45,5 % en poids à 76 % en poids, la teneur en acide glucuronique est de 11 % en poids à 19 % en poids, la teneur en galactose est de 4,5 % en poids à 14,5 % en poids, et la teneur en arabinose est de 5,5 % en poids à 18 % en poids. L'invention concerne également une composition pharmaceutique comprenant la composition de glucide. La composition de glucide et la composition pharmaceutique de la présente invention peuvent atteindre les effets de prise de soins de la peau, d'inhibition d'allergie cutanée, d'inhibition d'inflammation cutanée ou de soulagement de dermatite atopique.
(ZH) 本发明提供一种醣类组合物作为医药组成物及其用途。醣类组合物,包括岩藻糖、葡萄糖醛酸、半乳糖以及阿拉伯糖。以醣类组合物的总重量计,岩藻糖的含量为45.5重量%至76重量%,葡萄糖醛酸的含量为11重量%至19重量%,半乳糖的含量为4.5重量%至14.5重量%,阿拉伯糖的含量为5.5重量%至18重量%。提供一种包括上述醣类组合物的医药组成物。本发明提供一种醣类组合物与医药组成物,可具有保养皮肤、抑制皮肤过敏、抑制皮肤发炎或改善异位性皮肤炎的效果。
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