Processing

Please wait...

Settings

Settings

Goto Application

1. WO2022134332 - USE OF ALOESIN IN PREPARATION OF PRODUCT FOR PREVENTING OR TREATING OBESITY

Publication Number WO/2022/134332
Publication Date 30.06.2022
International Application No. PCT/CN2021/082124
International Filing Date 22.03.2021
IPC
A61K 31/352 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 36/896 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
88Liliopsida (monocotyledons)
896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
A61P 3/04 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
04Anorexiants; Antiobesity agents
CPC
A61K 31/352
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 36/886
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
88Liliopsida (monocotyledons)
886Aloeaceae (Aloe family), e.g. aloe vera
A61K 36/896
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
88Liliopsida (monocotyledons)
896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
A61P 3/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3Drugs for disorders of the metabolism
04Anorexiants; Antiobesity agents
Applicants
  • 海南医学院 HAINAN MEDICAL UNIVERSITY [CN]/[CN]
Inventors
  • 王燕 WANG, Yan
  • 李友宾 LI, Youbin
  • 谭银丰 TAN, Yinfeng
  • 王雪松 WANG, Xuesong
  • 徐俊裕 XU, Junyu
  • 曾婷婷 ZENG, Tingting
  • 崔雪 CUI, Xue
  • 陈煜 CHEN, Yu
  • 张雪映 ZHANG, Xueying
Agents
  • 海口汉普知识产权代理有限公司 HAIKOU HEIP INTELLECTUAL PROPERTY AGENCY CO., LTD
Priority Data
202011543880.924.12.2020CN
Publication Language Chinese (zh)
Filing Language Chinese (ZH)
Designated States
Title
(EN) USE OF ALOESIN IN PREPARATION OF PRODUCT FOR PREVENTING OR TREATING OBESITY
(FR) UTILISATION D'ALOÉSINE DANS LA PRÉPARATION D'UN PRODUIT POUR LA PRÉVENTION OU LE TRAITEMENT DE L'OBÉSITÉ
(ZH) 芦荟苦素在制备预防或治疗肥胖产品中的应用
Abstract
(EN) The use of aloesin in the preparation of a product for preventing or treating obesity. Aloesin can inhibit lipid accumulation, increase the expression of the browning genes UCP1 and PRDM16 and the transcription factor C-EBPα, improve the expression and release of the specific factor adiponectin, and inhibit the release of the non-specific factor IL-1β, indicating that aloesin can mediate the browning of 3T3-L1 adipocytes and can be used in the preparation of a product for preventing or treating obesity.
(FR) L'invention concerne l'utilisation d'aloésine dans la préparation d'un produit pour la prévention ou le traitement de l'obésité. L'aloésine permet d’inhiber l'accumulation de lipides, d’augmenter l'expression des gènes de brunissement UCP1 et PRDM16 et du facteur de transcription C-EBPα, d’améliorer l'expression et la libération du facteur spécifique de l'adiponectine, et d’inhiber la libération du facteur IL-1β non spécifique, indiquant que l'aloésine peut induire le brunissement des adipocytes 3T3-L1 et peut être utilisée dans la préparation d'un produit pour la prévention ou le traitement de l'obésité.
(ZH) 芦荟苦素在制备预防或治疗肥胖产品中的应用。芦荟苦素能够抑制脂质堆积,增加褐化基因UCP1和PRDM16及转录因子C-EBPα的表达,提高特异性因子脂联素的表达和释放,抑制非特异性因子IL-1β的释放,表明芦荟苦素能够介导3T3-L1脂肪细胞的褐化,可将芦荟苦素应用于制备预防或治疗肥胖产品。
Related patent documents
Latest bibliographic data on file with the International Bureau