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1. WO2022115486 - ANTIBODIES THAT BIND TO MULTIPLE BETACORONAVIRUSES

Publication Number WO/2022/115486
Publication Date 02.06.2022
International Application No. PCT/US2021/060631
International Filing Date 23.11.2021
IPC
A61P 31/14 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
C07K 16/10 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
A61P 31/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
C07K 16/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
08against material from viruses
10from RNA viruses ; , e.g. hepatitis E virus
C07K 2317/21
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
20characterized by taxonomic origin
21from primates, e.g. man
C07K 2317/33
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
30characterized by aspects of specificity or valency
33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
C07K 2317/565
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
50characterized by immunoglobulin fragments
56variable (Fv) region, i.e. VH and/or VL
565Complementarity determining region [CDR]
Applicants
  • VIR BIOTECHNOLOGY, INC. [US]/[US]
  • HUMABS BIOMED SA [CH]/[CH]
Inventors
  • CORTI, Davide
  • PINTO, Dora
  • BELTRAMELLO, Martina
  • LEMPP, Florian A.
Agents
  • LECOINTE, Michelle, M.
  • MORGAN, John, A.
  • OBEIDAT, Baha, A.
  • ADRA, Bilal, H.
  • KUMABE, Blake, K.
  • SOLTANI, Bobby, B.
  • ZENTZ, Bradley, J.
  • SARGEANT, Brooke
  • QUIST, Brooke, W.
  • EIDT, Chandra, E.
  • O'BRIEN, Daniel
  • CARLSON, David, V.
  • CONLEE, David C.
  • STARK, Duncan
  • TARLETON, E., Russell
  • SUN, Eileen, S.
  • HARWOOD, Eric, A.
  • HAN, Hai
  • TALBERT, Hayley, J.
  • KHANNA, Hemant
  • PURUSHE, Janaki
  • BARRETT, Jared, M.
  • DANLEY, Jeffrey E.
  • SAKOI, Jeffrey, M.
  • BAUNACH, Jeremiah, J.
  • GRITTON, Jessica, S.
  • ZHANG, Jianping
  • WAKELEY, John, J.
  • COE, Justin, E.
  • HENCKEL, Karen, M.
  • HEFTER, Karl, A.
  • HERMANNS, Karl, R.
  • TOYAMA, Kazuya
  • MORGAN, Kevan, L.
  • COSTANZA, Kevin, S.
  • COOPER, Michael, P.
  • BENDEMIRE, Paul, D.
  • LIN, Qing
  • WEBB, Samuel, E.
  • LIU, Shi
  • LEEK, Shoko, I.
  • ROSENMAN, Stephen, J.
  • LAWRENZ, Steven, D.
  • ABEDI, Syed
  • BOLLER, Timothy, L.
  • SHEWMAKE, Thomas, A.
  • LIGON, Toby, J.
  • LI, Yiheng
  • SAKOI, Zachary, M.
Priority Data
63/118,47425.11.2020US
63/170,34202.04.2021US
63/177,72421.04.2021US
63/186,77910.05.2021US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) ANTIBODIES THAT BIND TO MULTIPLE BETACORONAVIRUSES
(FR) ANTICORPS SE LIANT À PLUSIEURS BÉTACORONAVIRUS
Abstract
(EN) The instant disclosure provides antibodies and antigen binding fragments thereof that can bind to S proteins of multiple betacoronaviruses and, in certain embodiments, are capable of neutralizing infection by multiple betacoronaviruses.
(FR) La présente divulgation concerne des anticorps et des fragments liant l'antigène de ceux-ci qui peuvent se lier à des protéines S de plusieurs bétacoronavirus et, dans certains modes de réalisation, peuvent neutraliser une infection par plusieurs bétacoronavirus.
Latest bibliographic data on file with the International Bureau