Processing

Please wait...

Settings

Settings

Goto Application

1. WO2022085007 - DEVICE, SYSTEMS AND METHODS FOR DETECTION OF NUCLEIC ACID MOLECULES OF INTEREST

Publication Number WO/2022/085007
Publication Date 28.04.2022
International Application No. PCT/IL2021/051253
International Filing Date 21.10.2021
IPC
B01L 3/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
B01L 7/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
7Heating or cooling apparatus; Heat insulating devices
C12Q 1/6865
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6844Nucleic acid amplification reactions
6865Promoter-based amplification, e.g. nucleic acid sequence-based amplification , self-sustained sequence replication or transcription-based amplification system
C12Q 1/6844
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6844Nucleic acid amplification reactions
C12Q 1/68
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
C12Q 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
CPC
B01L 3/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
B01L 7/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
7Heating or cooling apparatus
C12Q 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
C12Q 1/68
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
C12Q 1/6844
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6844Nucleic acid amplification reactions
C12Q 1/6865
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6844Nucleic acid amplification reactions
6865Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
Applicants
  • TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. [IL]/[IL]
Inventors
  • ROFMAN, Baruch
  • BERCOVICI, Moran
  • BEN-ASSA, Nadav
  • GEVA-ZATORSKY, Naama
  • NADDAF, Rawi
  • GEFEN, Tal
Agents
  • ZRIHAN-LICHT, Sheila
Priority Data
63/104,91423.10.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) DEVICE, SYSTEMS AND METHODS FOR DETECTION OF NUCLEIC ACID MOLECULES OF INTEREST
(FR) DISPOSITIF, SYSTÈMES ET PROCÉDÉS DE DÉTECTION DE MOLÉCULES D'ACIDE NUCLÉIQUE D'INTÉRÊT
Abstract
(EN) A sample testing module, for use with a device for enabling detection and monitoring of at least one target element in a sample, includes a reaction pad and a support. The reaction pad includes a preparation zone that is contiguous with a plurality of reaction zones via respective branch elements. The preparation zone is configured for: accommodating sample preparation agents and at least a sample to be tested, and for enabling mixing thereof to provide a prepared sample; accommodating a second quantity of a transporting liquid and for enabling contact of the prepared sample with the transporting liquid to provide the flowable prepared sample. Each reaction zone is configured for accommodating therein a respective reaction mixture adapted for the reaction, to produce at least one respective product. The support includes a first heating system (for enabling heating of the preparation zone to a first temperature) and a second heating system (for enabling heating of the amplification zones to a second temperature).
(FR) Un module d'essai d'échantillon, destiné à être utilisé avec un dispositif pour permettre la détection et la surveillance d'au moins un élément cible dans un échantillon, comprend un tampon de réaction et un support. Le tampon de réaction comprend une zone de préparation qui est contiguë à une pluralité de zones de réaction par l'intermédiaire d'éléments de ramification respectifs. La zone de préparation est configurée pour : recevoir des agents de préparation d'échantillon et au moins un échantillon à analyser, et pour permettre le mélange de ceux-ci pour fournir un échantillon préparé; recevoir une seconde quantité d'un liquide de transport et pour permettre le contact de l'échantillon préparé avec le liquide de transport pour fournir l'échantillon préparé fluide. Chaque zone de réaction est configurée pour recevoir dans celle-ci un mélange réactionnel respectif adapté à la réaction, pour produire au moins un produit respectif. Le support comprend un premier système de chauffage (pour permettre le chauffage de la zone de préparation à une première température) et un second système de chauffage (pour permettre le chauffage des zones d'amplification à une seconde température).
Latest bibliographic data on file with the International Bureau