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1. WO2022137002 - BLEEDING DETECTION METHOD

Publication Number WO/2022/137002
Publication Date 30.06.2022
International Application No. PCT/IB2021/061520
International Filing Date 09.12.2021
IPC
A61K 49/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
C12Q 1/56 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
56involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
CPC
A61B 2505/05
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
2505Evaluating, monitoring or diagnosing in the context of a particular type of medical care
05Surgical care
A61B 5/0071
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
0059using light, e.g. diagnosis by transillumination, diascopy, fluorescence
0071by measuring fluorescence emission
A61B 5/02042
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
02042Determining blood loss or bleeding, e.g. during a surgical procedure
A61K 49/0013
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
001Preparation for luminescence or biological staining
0013Luminescence
A61K 49/0021
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
001Preparation for luminescence or biological staining
0013Luminescence
0017Fluorescence in vivo
0019characterised by the fluorescent group
0021the fluorescent group being a small organic molecule
A61K 49/0056
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
001Preparation for luminescence or biological staining
0013Luminescence
0017Fluorescence in vivo
005characterised by the carrier molecule carrying the fluorescent agent
0056Peptides, proteins, polyamino acids
Applicants
  • ETHICON, INC. [US]/[US]
Inventors
  • DEANGLIS, Ashley
  • GHODBANE, Salim A.
  • DHANARAJ, Sridevi
  • AITKEN, Brian
Agents
  • SHIRTZ, Joseph F.
  • CRICHTON, David R.
Priority Data
63/128,59421.12.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) BLEEDING DETECTION METHOD
(FR) MÉTHODE DE DÉTECTION DE SAIGNEMENT
Abstract
(EN) Disclosed are devices for detection of bleeding during surgical procedures and uses thereof. Also disclosed are methods of localizing a bleeding site during surgical procedures, and methods for evaluating an intensity of bleeding during the surgical procedures. The detection of bleeding is based, inter alia, on the presence of thrombin activity in a bleeding site.
(FR) L'invention concerne des dispositifs de détection de saignement pendant des interventions chirurgicales et leurs utilisations. L'invention concerne également des méthodes pour localiser un site de saignement pendant des interventions chirurgicales, ainsi que des procédés pour évaluer l'intensité d'un saignement pendant des interventions chirurgicales. La détection de saignement est basée, entre autres, sur la présence d'une activité de la thrombine sur un site de saignement.
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