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1. WO2021207306 - RECOMBINANT BACTERIA FOR USE AS A VACCINE TO PREVENT COVID19 INFECTION

Publication Number WO/2021/207306
Publication Date 14.10.2021
International Application No. PCT/US2021/026106
International Filing Date 07.04.2021
IPC
A61K 39/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
C12N 7/00 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
7Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof
A61K 39/215 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
215Coronaviridae, e.g. avian infectious bronchitis virus
CPC
A61K 2039/523
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
51comprising whole cells, viruses or DNA/RNA
52Bacterial cells; Fungal cells; Protozoal cells
523expressing foreign proteins
A61K 2039/543
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
54characterised by the route of administration
541Mucosal route
543intranasal
A61K 39/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
A61P 31/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
C07K 14/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
C07K 2319/03
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2319Fusion polypeptide
01containing a localisation/targetting motif
03containing a transmembrane segment
Applicants
  • SYNLOGIC OPERATING COMPANY, INC. [US]/[US]
Inventors
  • GAO, Jian-Rong
  • KURTZ, Caroline
  • SOKOLOVSKA, Anna
  • LI, Ning
Agents
  • CLARKE, Marcie, B.
  • BAI, Mei
  • BAYNE, Christopher, D.
  • BENNETT, Coalton, Sundiata
  • BLAZESKI, George
Priority Data
63/006,60407.04.2020US
63/065,77414.08.2020US
63/079,55117.09.2020US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) RECOMBINANT BACTERIA FOR USE AS A VACCINE TO PREVENT COVID19 INFECTION
(FR) BACTÉRIES RECOMBINANTES DESTINÉES À ÊTRE UTILISÉES EN TANT QUE VACCIN POUR PRÉVENIR UNE INFECTION PAR COVID19
Abstract
(EN) Modified microorganisms, pharmaceutical compositions thereof, and methods of preventing and treating the coronavirus disease 2019 (COVID-19) are disclosed.
(FR) L'invention concerne des micro-organismes modifiés, des compositions pharmaceutiques de ceux-ci, et des procédés de prévention et de traitement de la maladie de coronavirus 2019 (COVID-19).
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