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1. WO2021178661 - COMPOSITIONS CONTAINING A PATHOGENIC ANTIGEN AND AN IMMUNE STIMULATOR

Publication Number WO/2021/178661
Publication Date 10.09.2021
International Application No. PCT/US2021/020863
International Filing Date 04.03.2021
IPC
A61K 39/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
A61K 39/39 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
39characterised by the immunostimulating additives, e.g. chemical adjuvants
A61K 39/215 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
215Coronaviridae, e.g. avian infectious bronchitis virus
A61K 9/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
C12N 15/85 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79Vectors or expression systems specially adapted for eukaryotic hosts
85for animal cells
C07K 14/005 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
CPC
A61K 2039/53
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
51comprising whole cells, viruses or DNA/RNA
53DNA (RNA) vaccination
A61K 2039/54
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
54characterised by the route of administration
A61K 2039/545
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
545characterised by the dose, timing or administration schedule
A61K 2039/55538
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
555characterised by a specific combination antigen/adjuvant
55511Organic adjuvants
55522Cytokines; Lymphokines; Interferons
55527Interleukins
55538IL-12
A61K 2039/575
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
57characterised by the type of response, e.g. Th1, Th2
575humoral response
A61K 31/7088
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7088Compounds having three or more nucleosides or nucleotides
Applicants
  • ONCOSEC MEDICAL INCORPORATED [US]/[US]
Inventors
  • MUKHOPADHYAY, Anandaroop
  • RODRIGUEZ, John
  • CANTON, David A.
  • TWITTY, Christopher G.
  • JAFFE, Kim
  • O'CONNOR, Daniel J.
Agents
  • EKENA, Kirk
  • SKELTON, Bryan L.
  • SCHILLING, Stephen H.
  • KEITH, Jason A.
  • SANDERS, Marisa
Priority Data
62/985,19204.03.2020US
62/994,37525.03.2020US
63/001,35329.03.2020US
63/142,22927.01.2021US
63/142,25027.01.2021US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS CONTAINING A PATHOGENIC ANTIGEN AND AN IMMUNE STIMULATOR
(FR) COMPOSITIONS CONTENANT UN ANTIGÈNE PATHOGÈNE ET UN STIMULATEUR IMMUNITAIRE
Abstract
(EN) Described are compositions comprising a pathogenic antigen and an immune stimulator for use in inducing an immune response to a pathogen. Also described are compositions comprising an immunostimulatory cytokine and a pathogenic antigen for use in treating cancer.
(FR) L'invention concerne des compositions comprenant un antigène pathogène et un stimulateur immunitaire pour une utilisation dans l'induction d'une réponse immunitaire à un pathogène. L'invention concerne également des compositions comprenant une cytokine immunostimulatrice et un antigène pathogène pour une utilisation dans le traitement du cancer.
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