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1. WO2022013412 - COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS BY VIRUS OF THE FAMILY CORONAVIRIDAE

Publication Number WO/2022/013412
Publication Date 20.01.2022
International Application No. PCT/EP2021/069920
International Filing Date 16.07.2021
IPC
C07D 215/52 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
215Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
02having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
16with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
50attached in position 4
52with aryl radicals attached in position 2
A61P 31/14 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
A61K 31/47 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
Applicants
  • CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS [ES]/[ES]
Inventors
  • GUTIÉRREZ RODRÍGUEZ, Marta
  • IZQUIERDO GARCÍA, Carolina
  • GASTAMINZA LANDART, Pablo
  • GARAIGORTA DE DIOS, Urtzi
Agents
  • ABG INTELLECTUAL PROPERTY LAW, S.L.
Priority Data
20382647.417.07.2020EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) COMPOUNDS FOR USE IN THE TREATMENT OF VIRAL INFECTIONS BY VIRUS OF THE FAMILY CORONAVIRIDAE
(FR) COMPOSÉS DESTINÉS À ÊTRE UTILISÉS DANS LE TRAITEMENT D'INFECTIONS VIRALES PAR UN VIRUS DE LA FAMILLE DES CORONAVIRIDAE
Abstract
(EN) The present invention relates to new derivatives of 2-phenyl-quinoline-4-carboxylic acid or pharmaceutically acceptable salt thereof and to combination of said compounds with other active ingredients, for use in the treatment and/or prevention of viral infections by virus from the family Coronaviridae, to the use of said compound or its combinations in the manufacture of a medicament for the treatment or prevention of said diseases and to a method of treating and/or preventing said diseases by administration of said compound or its combinations.
(FR) La présente invention concerne de nouveaux dérivés d'acide 2-phényl-quinoléine-4-carboxylique ou un sel pharmaceutiquement acceptable de ceux-ci et une combinaison de ces composés avec d'autres principes actifs, destinés à être utilisés dans le traitement et/ou la prévention d'infections virales par un virus de la famille des coronaviridae, l'utilisation dudit composé ou de ses combinaisons dans la fabrication d'un médicament pour le traitement ou la prévention desdites maladies et un procédé de traitement et/ou de prévention desdites maladies par administration dudit composé ou de ses combinaisons.
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