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IC:G01N33/569

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Analysis

1.WO/2020/233147INERT CARRIER ESCHERICHIA COLI AND POTENTIAL USE THEREOF
WO 26.11.2020
Int.Class C12N 1/20
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
20Bacteria; Culture media therefor
Appl.No PCT/CN2020/071625 Applicant YANGZHOU UNIVERSITY Inventor ZHU, Guoqiang
Disclosed are an inert carrier Escherichia coli and the use thereof, wherein the inert carrier Escherichia coli has been deposited in the China General Microbiological Culture Collection Center (CGMCC), with a deposit address of Beijing, China, a deposit number of CGMCC No. 17339, a deposit date of March 18, 2019, a classification name of Escherichia coli, and a strain code of SE1. The Escherichia coli does not cause any macroscopic agglutination reaction with various chicken sera of different genetic backgrounds, i.e., does not generate a non-specific agglutination reaction with different kinds of chicken sera, has the properties of being expressed and displayed on the surface a specific antigen protein, and is used as an inert carrier in an indirect agglutination test for detecting antigens or antibodies.
2.WO/2020/235607METHOD FOR DETECTING TARGET MOLECULE
WO 26.11.2020
Int.Class G01N 37/00
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
37Details not covered by any other group of this subclass
Appl.No PCT/JP2020/019992 Applicant TOPPAN PRINTING CO., LTD. Inventor HIRASE Takumi
This method for detecting a surface target molecule and an internal target molecule of a structure comprises steps for: bringing a liquid having a structure dispersed therein into contact with a well array having a plurality of wells so as to introduce the structure into the wells; bringing an encapsulation liquid into contact with the well array so as to cause the structure to be encapsulated within each of the wells; extracting content of the structure within each of the wells; detecting at least one type of surface target molecule present on the surface of the structure within each of the wells; and detecting at least one type of internal target molecule present inside the structure within each of the wells.
3.WO/2020/236875MADCAM TARGETED IMMUNOTOLERANCE
WO 26.11.2020
Int.Class C07K 14/705
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
Appl.No PCT/US2020/033707 Applicant PANDION THERAPEUTICS, INC. Inventor HIGGINSON-SCOTT, Nathan
Methods and compounds for conferring site-specific or local immune privilege, such as targeting to a cell expressing MAdCAM. Disclosed herein are methods and therapeutic compounds that provide site-specific immune privilege. In some embodiments, the therapeutic compound comprises an engineered multi-specific compound, e.g., an engineered bi-specific molecule, e.g., an engineered bi-specific antibody molecule.
4.WO/2020/237044BACTERIOPHAGES FOR THE TREATMENT OF TUBERCULOSIS
WO 26.11.2020
Int.Class A61K 35/76
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
76Viruses; Subviral particles; Bacteriophages
Appl.No PCT/US2020/033985 Applicant UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION Inventor HATFULL, Graham
The invention provides a composition (e.g., pharmaceutical composition) comprising a combination of two or more phages, wherein the phages are two or more of: (a) phage D29; (b) phage Adephagia∆41∆43; (c) phage Fionnbharth∆47; (d) phage Fred313cpm-1; and (e) phage MuddyHRMN0052-1; and a pharmaceutically acceptable carrier. The invention provides a method of treating, reducing, or preventing a disease caused by Mycobacterium tuberculosis in a mammal comprising administering a pharmaceutical composition comprising a combination of two or more phages wherein the phages are two or more of: (a) phage D29; (b) phage Adephagia∆41∆43; (c) phage Fionnbharth∆47; (d) phage Fred313cpm-1; and (e) phage MuddyHRMN0052-1; and a pharmaceutically acceptable carrier. The composition can be administered alone or in combination with one or more antibiotics, wherein the length of treatment is reduced as compared to the length of treatment with one or more antibiotics alone.
5.WO/2020/233503DETECTION METHOD
WO 26.11.2020
Int.Class C07K 16/28
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
Appl.No PCT/CN2020/090425 Applicant UNIVERSITY OF MACAU Inventor WONG, Hang Heng
Provided is a method for assessing cytotoxicity of a cytotoxic cell that includes culturing a plurality of the cytotoxic cells with a plurality of target cells in a microfluidic device and determining whether the cytotoxic cells have a cytotoxic effect on the target cells, such as by determining a cell count and/or status of the cytotoxic cells and/or the target cells. A kit and a system for use in the aforementioned method are also provided.
6.WO/2020/236753METHODS OF IDENTIFYING HIV PATIENTS SENSITIVE TO THERAPY WITH GP120 V3 GLYCAN-DIRECTED ANTIBODIES
WO 26.11.2020
Int.Class A61K 39/42
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
42viral
Appl.No PCT/US2020/033470 Applicant GILEAD SCIENCES, INC. Inventor MOLDT, Brian
Provided are methods for identifying patient populations infected with HIV that can be targeted by antibodies that bind to HIV gl20 V3 glycan region.
7.WO/2020/236811DRUG-RESISTANT INFLUENZA VIRUS STRAINS
WO 26.11.2020
Int.Class A61P 31/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
16for influenza or rhinoviruses
Appl.No PCT/US2020/033590 Applicant PRESIDENT AND FELLOWS OF HARVARD COLLEGE Inventor INGBER, Donald, E.
This disclosure provides immunogenic compositions and methods of producing immunogenic compositions sufficient to produce an antigen-specific immune response against variant influenza virus strains. Also provided herein are methods of identifying drug-resistant influenza virus strains.
8.WO/2020/233148INERT CARRIER SALMONELLA SP. AND POTENTIAL APPLICATION THEREOF
WO 26.11.2020
Int.Class C12N 1/20
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
20Bacteria; Culture media therefor
Appl.No PCT/CN2020/071626 Applicant YANGZHOU UNIVERSITY Inventor ZHU, Guoqiang
Provided is an inert carrier Salmonella sp. S9 and an application thereof. The deposit number of the inert carrier Salmonella sp. is CGMCC No.17340, and the deposit date is March 18, 2019. The Salmonella sp. has no macroscopic agglutination reaction with a variety of chicken-derived serums of different genetic backgrounds, and can express and display antigen factors on a bacteria surface, and can be applied in the development of new detection reagents.
9.20200362316VESICULAR STOMATITIS VECTORS ENCODING CRIMEAN-CONGO HEMORRHAGIC FEVER ANTIGEN
US 19.11.2020
Int.Class C12N 7/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
7Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof
Appl.No 16875056 Applicant Sergio E. Rodriguez Inventor Sergio E. Rodriguez

Certain embodiments are directed generally to compositions and methods related to recombinant vesicular stomatitis virus vectors (ΔGrVSV) encoding Crimean-Congo Hemorrhagic Fever glycoprotein precursor (CCHFV-GPC) and forming a recombinant vesicular stomatitis virus vector encoding Crimean-Congo Hemorrhagic Fever glycoprotein precursor (ΔGrVSV-CCHFV-GPC).

10.WO/2020/232405LASER-ENABLED LAB ON SKIN
WO 19.11.2020
Int.Class A61B 5/1468
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1468using chemical or electrochemical methods, e.g. by polarographic means
Appl.No PCT/US2020/033264 Applicant CALIFORNIA INSTITUTE OF TECHNOLOGY Inventor GAO, Wei
A lab-on-skin biosensor for detecting target molecule and vital sign monitoring, a method of manufacturing, and a method of using the same, wherein the lab-on-skin biosensor is fabricated with a microfluidics layer, a moisture resistant layer, a multimodal sensing layer comprising an electrode, and a logic circuit that may include a processor and non-transitory memory with computer executable instructions embedded thereon.