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Analysis

1.WO/2020/234287METHOD FOR PREPARING A PEPTIDE SAMPLE
WO 26.11.2020
Int.Class G01N 33/68
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
Appl.No PCT/EP2020/063944 Applicant CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER Inventor LEHMANN, Sylvain
The present application relates to a method for preparing a peptide sample from a biological sample, and to a method for detecting or quantifying proteins comprising said method for preparing a sample. The invention also relates to the use of these methods for the detection or monitoring of a condition or a disease.
2.WO/2020/232536ENZYMATIC PRODUCTION OF GLUCARIC ACID FROM GLUCURONIC ACID
WO 26.11.2020
Int.Class C12P 7/58
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
7Preparation of oxygen-containing organic compounds
40containing a carboxyl group
58Aldonic, ketoaldonic or saccharic acids
Appl.No PCT/CA2020/050658 Applicant THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO Inventor MASTER, Emma R.
Described herein are processes and enzymes for the enzymatic production of glucaric acid from glucuronic acid, and more specifically the enzymatic production of substituted glucaric acid from substituted glucuronic acid. Advantageously, the process and enzymes described herein make preferential use substituted glucuronic acid obtained from natural sources, such as underutilized hemicellulose stream from wood and agricultural biorefineries, to produce substantially enantiomerically pure substituted D-glucaric acid.
3.WO/2020/233506METHOD FOR IMPROVING PRODUCTION OF STREPTOMYCES POLYKETIDE COMPOUNDS
WO 26.11.2020
Int.Class C12P 17/18
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
17Preparation of heterocyclic carbon compounds with only O, N, S, Se, or Te as ring hetero atoms
18containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
Appl.No PCT/CN2020/090452 Applicant EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY Inventor ZHANG, Lixin
A method for improving the production of streptomyces polyketide compounds is provided. The method greatly improves the capability of the streptomyces polyketide compounds by strengthening a triacylglycerol decomposition pathway in streptomyces during the stationary phase. A method for switching the primary metabolism of streptomyces to the secondary metabolism, streptomyces producing polyketide compounds, and use thereof are also provided.
4.WO/2020/235946USE OF ENZYME THAT CLEAVES BOTH ALPHA- AND BETA-1,4-GLYCOSIDIC BONDS
WO 26.11.2020
Int.Class C12N 9/24
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14Hydrolases (3.)
24acting on glycosyl compounds (3.2)
Appl.No PCT/KR2020/006649 Applicant KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION Inventor KIM, Kyoung Heon
The present invention relates to use of an enzyme that cleaves both alpha- and beta-1,4-glycosidic bonds and, more particularly, the present invention provides α-L-fucosidase which has α-1,4-glucosidase and β-1,4-galactosidase activities and thus is capable of producing glucose and/or galactose, which are monosaccharides, from non-fucosylated saccharides. The enzyme has transglycosylation activity and thus produces maltooligosaccharides having a higher degree of polymerization than maltooligosaccharides used as a substrate, thereby being applicable to the development of high-value-added new materials in the food industry.
5.WO/2020/237226COMPOSITIONS AND METHODS FOR PRODUCING STEVIOL GLYCOSIDES
WO 26.11.2020
Int.Class C12P 19/56
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19Preparation of compounds containing saccharide radicals
44Preparation of O-glycosides, e.g. glucosides
56having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
Appl.No PCT/US2020/034417 Applicant ARZEDA CORP. Inventor ZANGHELLINI, Alexandre
The present invention provides compositions and methods for producing steviol glycosides, particularly rebD, rebM and isomers thereof. The method includes use of glycosyltransferases that can transfer a glucose moiety from non-UDP-sugar sugar donors to steviol glycosides.
6.WO/2020/233715ANTI-HEPATITIS B VIRUS ANTIBODIES AND USE THEREOF
WO 26.11.2020
Int.Class C07K 16/08
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
08against material from viruses
Appl.No PCT/CN2020/091890 Applicant XIAMEN UNIVERSITY Inventor LUO, Wenxin
Antibodies (especially humanized antibodies) against the hepatitis B surface antigen (HBsAg), a nucleic acid molecule encoding same, a method for preparing same, and a pharmaceutical composition containing same. The anti-HBsAg antibodies have a higher binding affinity to HBsAg at a neutral pH than at an acidic pH, thereby significantly enhancing virus clearance efficiency and prolonging virus inhibition time. The antibodies and pharmaceutical composition may be used to prevent and/or treat HBV infections or diseases related to HBV infection (such as hepatitis B) for use in neutralizing the virulence of HBV in the body of a subject (such as a human) to reduce a serum level of HBV DNA and/or HBsAg in the body of the subject, or to activate a humoral immune response of a subject (such as a person infected with chronic HBV or a patient who has chronic hepatitis B) against HBV.
7.WO/2020/234215BIOTIN PROTOTROPHY
WO 26.11.2020
Int.Class C12P 17/18
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
17Preparation of heterocyclic carbon compounds with only O, N, S, Se, or Te as ring hetero atoms
18containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
Appl.No PCT/EP2020/063762 Applicant TECHNISCHE UNIVERSITEIT DELFT Inventor DARAN, Jean-Marc, Georges
The present invention relates to a biological cell that can grow in the absence of biotin under aerobic conditions, comprising a BIO1 gene (i.e. CfBIO1), and preferably a BIO6, BIO2, BIO3, and BIO4 gene. The present disclosure additionally relates to a biological cell that can grow in the absence of biotin under aerobic and anaerobic conditions, comprising the genes fabD, bioC, fabB, fabG, fabZ, fabI, bioH, bioF, adpP, acpS, and preferably the genes BIO2, BIO3, and BIO4. The biological cell according to the disclosure may be a prokaryotic cell or an eukaryotic cell, preferably a yeast cell, such as a Saccharomycotina yeast, most preferably Saccharomyces cerevisiae.
8.WO/2020/237115METHODS OF FULL-LENGTH RNA PROFILING
WO 26.11.2020
Int.Class C12Q 1/68
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
Appl.No PCT/US2020/034127 Applicant THE ROCKEFELLER UNIVERSITY Inventor LIU, Shixin
The invention relates to the characterization of nucleic acid, particularly RNA, and to full-length transcript profiling of RNA. The invention relates to methods, aspects and kits for determining a transcriptome of an organism, including simultaneously capturing sequences of both the 5' and 3' termini of transcripts so as to characterize all transcripts or RNAs and to provide transcription start and termination sites of a transcriptome with nucleotide resolution.
9.WO/2020/233784STRAIN OF MICROORGANISMS AND PROCESS FOR THE FERMENTATIVE PRODUCTION OF GAMMA-GLUTAMYLTYROSINE AND GAMMA-GLUTAMYLPHENYLALANINE
WO 26.11.2020
Int.Class C12N 9/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
Appl.No PCT/EP2019/062957 Applicant WACKER CHEMIE AG Inventor SCHLÖSSER, Thomas
The invention relates to a process for the fermentative production of the substances gamma-glutamyltyrosine and gamma-glutamylphenylalanine using a strain of microorganisms that is cultivated in a fermentation medium, the fermentation medium is removed from the microorganisms after fermentation and gamma-glutamyltyrosine and gamma-glutamylphenylalanine are isolated from the fermentation medium. The strain of microorganisms contains at least one additional gene that codes for a glutamate-cysteine ligase and has a glutathione synthetase deficiency. The fermentation medium is preferably mixed with L-tyrosine and L-phenylalanine for culture.
10.WO/2020/234684PROCESS FOR RECLAMATION OF POLYESTER BY REACTOR ADDITION
WO 26.11.2020
Int.Class B29B 17/00
BPERFORMING OPERATIONS; TRANSPORTING
29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
BPREPARATION OR PRETREATMENT OF THE MATERIAL TO BE SHAPED; MAKING GRANULES OR PREFORMS; RECOVERY OF PLASTICS OR OTHER CONSTITUENTS OF WASTE MATERIAL CONTAINING PLASTICS
17Recovery of plastics or other constituents of waste material containing plastics
Appl.No PCT/IB2020/054363 Applicant OCTAL SAOC FCZ, SULTANATE OF OMAN Inventor JOSHI, Tarun
A method for reclaiming polyester can include: providing a feed of recycled polyester 420; providing a feed of polyester precursors 422; depolymerizing the recycled polyester 420 to obtain depolymerized polyester monomers 421; polymerizing the depolymerized polyester monomers 421 with the polyester precursors 422 to form a reclaimed polyester 423; and providing the reclaimed polyester 423 as output 102.