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1.WO/2020/235247ELECTROCHEMICAL DETECTION METHOD FOR PRODUCT OF CATALYZED REACTION, AND TRANSDUCER
WO 26.11.2020
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/JP2020/016079 Applicant JAPAN AVIATION ELECTRONICS INDUSTRY, LIMITED Inventor KUNIKATA, Ryota
A method for electrochemically detecting a catalyzed reaction product that is generated by a catalyzed reaction that proceeds in a first liquid mass 20 and is dissolved in the first liquid mass 20. The method involves forming the first liquid mass 20 and a second liquid mass 30 that contacts and forms a liquid-liquid interface with the first liquid mass 20 and does not dissolve the catalyzed reaction product in a liquid tank 10, arranging a working electrode 40 inside the first liquid mass 20, arranging a counter electrode 50 and a reference electrode 60 inside the second liquid mass 30, and detecting the current that flows in the working electrode 40 as a result of the catalyzed reaction product being involved in an oxidation or reduction reaction at the working electrode 40.
2.WO/2020/235607METHOD FOR DETECTING TARGET MOLECULE
WO 26.11.2020
Int.Class G01N 37/00
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
37Details not covered by any other group of this subclass
Appl.No PCT/JP2020/019992 Applicant TOPPAN PRINTING CO., LTD. Inventor HIRASE Takumi
This method for detecting a surface target molecule and an internal target molecule of a structure comprises steps for: bringing a liquid having a structure dispersed therein into contact with a well array having a plurality of wells so as to introduce the structure into the wells; bringing an encapsulation liquid into contact with the well array so as to cause the structure to be encapsulated within each of the wells; extracting content of the structure within each of the wells; detecting at least one type of surface target molecule present on the surface of the structure within each of the wells; and detecting at least one type of internal target molecule present inside the structure within each of the wells.
3.WO/2020/235206CULTURE CONTAINER FOR CULTURING EPITHELIAL CELLS AND USE THEREOF
WO 26.11.2020
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/JP2020/012585 Applicant KEIO UNIVERSITY Inventor SATO Toshiro
A culture container for culturing epithelial cells that comprises an upper container, a lid member air tightly fitting into the opening of the upper container, and a lower container housing the upper container and a cell culture medium therein, wherein; at least a part of an area of the upper container, said area being in contact with the cell culture medium, is formed of a membrane that is permeable to at least some components of the cell culture medium and impermeable to cells; and the material of the lid member has an oxygen permeation coefficient of not more than 1.0×10-6 cm3 cm/(cm2 s•Pa).
4.WO/2020/237076APPARATUS AND METHOD FOR RAPID IDENTIFICATION OF MICROORGANISMS
WO 26.11.2020
Int.Class B01F 11/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
11Mixers with shaking, oscillating, or vibrating mechanisms
Appl.No PCT/US2020/034047 Applicant CITROGENE INC. Inventor HOSSEINI, S., Abbas
An apparatus and method is disclosed for rapid identification of a microorganism within sampling device. The sampling device has a plurality of reaction chambers each having a different reactive agent for reacting with the microorganism to indicate the presence of a microorganism in said reaction chamber. A detector detects each of the plurality of reaction chamber for detecting the presence of a microorganism in said reaction chamber. The invention automates CRISPR CAS 12 and/or CAS 13 method. The invention is a general platform for detection of segments of DNA or RNA using CRSIPR CAS 12 and/or CAS 13 proteins.
5.WO/2020/235574THREE-LAYER LAMINATE CONSTITUTED OF EXTRACELLULAR MATRIX, SHEET-SHAPED CELL CULTURE, AND BIODEGRADABLE GEL IN THAT ORDER
WO 26.11.2020
Int.Class C12M 3/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
3Tissue, human, animal or plant cell, or virus culture apparatus
Appl.No PCT/JP2020/019847 Applicant TERUMO KABUSHIKI KAISHA Inventor OHASHI, Fumiya
The present invention addresses the problem of providing a laminate that is easier to manipulate, in which when a thrombin solution is sprayed, damage to a sheet-shaped cell culture due to the spraying pressure is reduced, and a fibrin gel is formed on one surface of the sheet-shaped cell culture. This problem is solved by: in the production of a sheet-shaped cell culture in which cells are cultured on a temperature-responsive cell culture substrate, fibrinogen is instilled on a sheet-shaped cell culture having an extracellular matrix on the bottom surface, and furthermore, a thrombin solution is sprayed onto the sheet-shaped cell culture from an oblique direction; and by providing a laminate having a fibrin gel layer only on one surface of the sheet-shaped cell culture, and having an extracellular matrix layer on the other surface.
6.WO/2020/237104AUTOLOGOUS CELL REPLACEMENT THERAPY FOR PARKINSON'S DISEASE
WO 26.11.2020
Int.Class A61K 35/30
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
30Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
Appl.No PCT/US2020/034098 Applicant THE MCLEAN HOSPITAL CORPORATION Inventor KIM, Kwang-Soo
Methods for generating midbrain dopamine (mDA) neuronal progenitor cells useful for autologous cell therapy in Parkinson's Disease, compositions comprising the cells, and methods of use thereof.
7.WO/2020/235243TUBE CLIP AND CULTURE RECORDING SYSTEM
WO 26.11.2020
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/JP2020/015772 Applicant YOKOGAWA ELECTRIC CORPORATION Inventor HIRANO, Akinari
The present invention addresses the problem of supporting the realization of the automatic recording of a culture solution delivery operation in cell culturing. A tube clip which is intended to be attached to an elastic tube for culture solution delivery use, is equipped with an opening/closing mechanism so that the switching between an opened state and a closed state of the elastic tube can be achieved by opening or closing the opening/closing mechanism, the tube clip being provided with an opening/closing detection section which can detect the opening or closing state of the opening/closing mechanism, a measurement section which can work during a time period where the opening/closing detection mechanism detects an opened state of the opening/closing mechanism and which can measure the state of flow of a culture solution in the elastic tube in a non-contacting manner, and a transmission section which can output a signal based on a result of the measurement by the measurement section to the outside.
8.WO/2020/235253SORTING METHOD AND SORTING DEVICE
WO 26.11.2020
Int.Class C12M 1/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
34Measuring or testing with condition measuring or sensing means, e.g. colony counters
Appl.No PCT/JP2020/016236 Applicant PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. Inventor SUZUKI Kaori
This sorting method comprises: a holding step for holding a plurality of spheroids (50) without contacting a plurality of measurement electrodes (30); an acquisition step for acquiring a plurality of signals related to a plurality of extracellular potentials of the plurality of spheroids (50) by using the plurality of measurement electrodes (30); a determination step for determining whether the plurality of spheroids (50) are each good or not, on the basis of a signal which corresponds to a spheroid (50) and is included in the plurality of signals, the plurality of spheroids (50) being one-to-one correspondent to the plurality of signals; and a collection step for collecting one or a plurality of spheroids, which are determined to be good in the determination step, among the plurality of spheroids.
9.WO/2020/235283ANALYSIS DEVICE AND ANALYSIS METHOD
WO 26.11.2020
Int.Class C12M 1/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
Appl.No PCT/JP2020/017202 Applicant HITACHI HIGH-TECH CORPORATION Inventor ANAZAWA Takashi
In analysis methods and analysis devices for identifying light emitted by multiple types of fluorescent bodies from a plurality of light emission points by detecting florescent light from each light emission point at each of a plurality of wavelength bands, spatial crosstalk and spectral crosstalk exist between signal intensities of the plurality of light emission points and between those of the plurality of wavelength bands, resulting in reduced identification performance. In the present invention, all detection signals of the plurality of wavelength bands from each of the plurality of light emission points are input to a predetermined formula to cancel the spatial crosstalk and spectral crosstalk and derive the concentration of each fluorescent body at each light emission point.
10.WO/2020/237103METHODS AND SYSTEMS FOR EFFICIENT BIOREACTOR MIXING AND LIGHT UTILIZATION EMBODYING LOW PROCESS ENERGY AND SCALABILITY
WO 26.11.2020
Int.Class C12M 1/02
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1Apparatus for enzymology or microbiology
02with agitation means; with heat exchange means
Appl.No PCT/US2020/034097 Applicant SOLARCLEAN FUELS, LLC Inventor FALCO, Robert E.
Embodiments of the present invention may provide fluid flow coordinators (92), passive flow field modifiers (93), or even inwardly protruding helical spines (3) which can be used in continuous, scalable, low energy usage, bioreactor systems (1) perhaps to provide optimal mixing of microorganisms with nutrients (11), gases (95), or the like or even to move microorganisms (132), such as algae, in and out of light for effective and optimal growth.