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1. WO2021067697 - METHODS AND MATERIALS FOR TREATING NEUROTOXICITY

Publication Number WO/2021/067697
Publication Date 08.04.2021
International Application No. PCT/US2020/053944
International Filing Date 02.10.2020
IPC
A61K 31/405 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403condensed with carbocyclic rings, e.g. carbazole
404Indoles, e.g. pindolol
405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
A61K 35/17 2015.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
14Blood; Artificial blood
17Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
A61K 39/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
Applicants
  • CAVION, INC. [US]/[US]
Inventors
  • MARICICH, Yuri
  • NEWBOLD, Evan
  • CAVALETTI, Guido
  • MEREGALLI, Cristina
Agents
  • REANEY, Shannon
Priority Data
62/909,69402.10.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND MATERIALS FOR TREATING NEUROTOXICITY
(FR) PROCÉDÉS ET MATÉRIAUX POUR LE TRAITEMENT DE LA NEUROTOXICITÉ
Abstract
(EN)
This document relates to methods and materials for treating a mammal having neurotoxicity (e.g., chemotherapy-induced neurotoxicity). For example, one or more T-type calcium channel modulators (e.g., a composition including one or more T-type calcium channel modulators such as CX-8998) can be administered to a mammal having neurotoxicity to treat the mammal.
(FR)
L'invention concerne des procédés et des matériaux pour traiter un mammifère présentant une neurotoxicité (par exemple, une neurotoxicité induite par chimiothérapie). Par exemple, un ou plusieurs modulateurs des canaux calciques de Type T (par exemple, une composition comprenant un ou plusieurs modulateurs des canaux calciques de type T tels que le CX-8998) peut être administrée à un mammifère présentant une neurotoxicité pour traiter le mammifère.
Latest bibliographic data on file with the International Bureau