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1. WO2021003078 - INHIBITORS OF PROTEIN ARGININE DEIMINASE 1 AND METHODS OF PREPARATION AND USE THEREOF

Publication Number WO/2021/003078
Publication Date 07.01.2021
International Application No. PCT/US2020/039967
International Filing Date 26.06.2020
IPC
C07D 235/14 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
06with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
14Radicals substituted by nitrogen atoms
Applicants
  • UNIVERSITY OF MASSACHUSETTS [US]/[US]
Inventors
  • THOMPSON, Paul, R.
  • MONDAL, Santanu
Agents
  • ZHANG, Yin, Philip
Priority Data
62/870,63103.07.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) INHIBITORS OF PROTEIN ARGININE DEIMINASE 1 AND METHODS OF PREPARATION AND USE THEREOF
(FR) INHIBITEURS DE LA PROTÉINE ARGININE DÉIMINASE (PAD) ET LEURS MÉTHODES DE PRÉPARATION ET D'UTILISATION
Abstract
(EN)
The invention provides novel inhibitors or inactivators of protein arginine deiminase 1, pharmaceutical compositions and methods of use thereof. The invention also relates to molecular probes based on such compounds and methods of use thereof.
(FR)
L'invention concerne de nouveaux inhibiteurs ou inactivateurs de la protéine arginine déiminase 1, des compositions pharmaceutiques, ainsi que leurs méthodes d'utilisation. L'invention concerne également des sondes moléculaires à base desdits composés, ainsi que leurs méthodes d'utilisation.
Latest bibliographic data on file with the International Bureau