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1. WO2020183457 - CANNABINOID COMBINATIONS FOR TREATING DIABETIC NEUROPATHY

Publication Number WO/2020/183457
Publication Date 17.09.2020
International Application No. PCT/IL2020/050272
International Filing Date 09.03.2020
IPC
A61K 31/352 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 31/03 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
02Halogenated hydrocarbons
025carbocyclic
03aromatic
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61K 47/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
A61K 36/185 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
A61P 25/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
04Centrally acting analgesics, e.g. opioids
Applicants
  • BOL PHARMA LTD. [IL]/[IL]
Inventors
  • GEDO, Tamir
Agents
  • STRICHMAN-ALMASHANU, Liora
  • STRICHMAN-ALMASHANU, Liora
Priority Data
62/816,18810.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CANNABINOID COMBINATIONS FOR TREATING DIABETIC NEUROPATHY
(FR) COMBINAISONS DE CANNABINOÏDES POUR TRAITER UNE NEUROPATHIE DIABÉTIQUE
Abstract
(EN)
The present invention is directed to a cannabinoid combination comprising, as the only cannabinoids, cannabidiol (CBD) and A9-tetrahydrocannabinol (THC), or enantiomers, diastereomers, or racemates thereof, for use in the treatment of diabetic neuropathy in a subject, or for improving the efficacy and/or reducing adverse effects of a standard of care (SoC) drug for treating neuropathic pain, wherein the CBD:THC weight ratio in the cannabinoid combination is about of 4:1 to about 10:1.
(FR)
La présente invention concerne une combinaison de cannabinoïdes comprenant, en tant que seuls cannabinoïdes, le cannabidiol (CBD) et l'A9-tétrahydrocannabinol (THC), ou des énantiomères, des diastéréomères ou des racémates de ceux-ci, destinés à être utilisés dans le traitement d'une neuropathie diabétique chez un sujet, ou pour améliorer l'efficacité et/ou réduire les effets secondaires d'un médicament standard de soins (SoC) pour traiter une douleur neuropathique, le rapport pondéral CBD:THC dans la combinaison de cannabinoïdes étant d'environ 4:1 à environ 10:1.
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